<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22826

Description ATP-dependent DNA helicase Q-like 4A
SequenceMQANNKLPRVNWPQHANAIEGSSSKDDFLSSSFLFSLPTQRPNPEANREGMLSLRSYACKIQGPERLQVPWIEKAWRSLCNTQVACKSYLRPGLSAKVKDCDRGHAPTYGGGAYNINKMATLPGNRMLSQESTHQPSENGPVENNSIHQPAGIDSSARTYQSNHVVQADIMRPTNRYIRTNAELHQPAPVADSMCTDYDLDAMDDDDILASIDVDRIVMEHYQATNTPKGSVSHNISTPPGNKCTFNGVDETNLPQELSELCNHQCKLAFCPQAMVHLQEMKDELIAVANELLDDDGELNLQRSEELRKKRLQLKKQIQLLEEYLMRSAQDEERQRSHSMASTTAILGHVPPMTPGSTFIMDSNSFQSQVYVRNGPGNSDLCYSPAPYSCPDNLSTPMNSVWREYTPKVIDINYTEGSDDKKWSSTNFPWTKELEAKNRNKFGNRSFRPNQREIINATMSGNDVFVLMPTGGGKSLTYQLPALISEGLTLVVCPLVSLIEDQIMHLSQANIPATYLSASIEWSEQQEILRDLMSCHYKLLYVTPEKIAKSDTLSRLLNNLYFQGHLSRIVIDEAHCVSQWGHDFRPDYKNLGVLKQHFPKTPVLALTATATARVKEDVVQALGLANCIVFRQSFNRSNLRYFLRPKTKKCLEDIDNFIHKNHFKECGIIYCLSRMDCEKVAEKLRDCGHNVSHYHGSMDPVDRTRVQKQWSKDRINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCVLYYQYSDYIRVRHMLTQGVAEQTVAPRGGYSNSHEQALKTHKENLLHMVSYCENDVDCRRLLQLIHFGERFDPSLCAKTCDNCLKELTWVEKDVTNIARQLVELVTMTGQSSSSSHILEVYRGSVSQNVKKQRHDALPLHGAGKHLARGEAARIMRHLVTEGILIEDVKRSDNIYGSISSVLKANQLKASELRSGKHSIVLKFPASDKASKMGKLDVSSFPQINKIAHQQSEVDENLASMLFDALVTLREQIMDECNEGYHAYHIFKKDTLKEMSIRVPRTKEELLEINGIGKAKVKKYGDRVLATIEDFLSKHPNPRRNSSGSGSNEHTEAAKKRRGFTASYAGSNGEDDFEGRTVQSKKRPAKTRSTKQGVSDAASMVHGARCMDADLDGVEALDDELCSVQKPVASGRVLPKWAPAKAKSSSVPPSNLFQEFGYVK
Length1204
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.07
Grand average of hydropathy-0.550
Instability index50.65
Isoelectric point8.14
Molecular weight135110.58
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22826
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.18|      18|      20|     650|     667|       2
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  650-  667 (34.77/27.06)	CLEDIDNFIHKNHFKECG
  671-  688 (33.41/25.66)	CLSRMDCEKVAEKLRDCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.12|      17|      21|     428|     447|       4
---------------------------------------------------------------------------
  429-  447 (27.53/24.37)	PWTKELeaKNRNKFGNRSF
  449-  465 (30.59/14.72)	PNQREI..INATMSGNDVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.26|      19|      22|    1033|    1051|       5
---------------------------------------------------------------------------
 1033- 1051 (31.24/19.26)	KDTLKEMSIRVPRTKEELL
 1058- 1076 (31.02/19.08)	KAKVKKYGDRVLATIEDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     285.82|      86|     142|     693|     784|       6
---------------------------------------------------------------------------
  571-  600 (22.63/ 6.92)	..............IDEAHCVSQ..W.GHD..........F.........RPDYKnlGVLKQHFPK...........................................
  693-  784 (151.43/124.72)	HYHGSMDP......VDRTRVQKQ..W.SKDRINIICATVAF....GMGINKPDVR..FVIHHSLPKsiegyhQECGRAGRDGQP.SSCVLYYQYSDYIRV.RHMLTQGV
  831-  928 (111.76/78.90)	HFGERFDPslcaktCDN..CLKEltWvEKDVTNIARQLVELvtmtGQSSSSSHIL..EVYRGSVS.......QNVKKQRHDALPlHGAGKHLARGEAARImRHLVTEGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.67|      10|      21|     376|     385|       7
---------------------------------------------------------------------------
  376-  385 (21.66/12.19)	PGNSDL.CYSP
  397-  407 (18.00/ 8.94)	PMNSVWrEYTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.07|      35|      35|     136|     170|       8
---------------------------------------------------------------------------
  107-  133 (39.70/18.43)	PTYGGGAYN..INKMA........TLPGNRMLsQEST
  136-  170 (61.00/31.82)	PSENGPVENNSIHQPAGI.DSSARTYQSNHVV.QADI
  173-  208 (57.37/29.54)	PTNRYIRTNAELHQPAPVaDSMCTDYDLDAMD.DDDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.87|      10|      23|     301|     310|       9
---------------------------------------------------------------------------
  301-  310 (16.68/ 9.93)	LQRS..EELRKK
  325-  336 (13.19/ 6.35)	LMRSaqDEERQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.37|      29|     905|     225|     258|      11
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  225-  253 (53.50/29.19)	TNTPKGSVSHNISTPPGNKCTFNGVDETN
 1131- 1159 (47.88/24.80)	TRSTKQGVSDAASMVHGARCMDADLDGVE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22826 with Med34 domain of Kingdom Viridiplantae
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