<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22824

Description U-box domain-containing protein 34-like
SequenceMASGGPPPTVAVAVAVRPGGSGSRLAARWVAAGLPDDGRAASVAVVHVIPTLSHVPSPTGERVPVTLVGREPAQAYARDRRARAEEALLPFRHLNCRRANVTVETVVVEGDGVAEALLRYARESGVRSLVLGAASFRWFRRVLSIPDVPGTVIQATQSSCNVFVVSKRRLIMKLARYPQTSGPNGNLRIEAISHEAFEQSHRSLLFDSFADDEARSDAFSHAHSSHGASNVVPSSESSEQVASESSVANAAGAEGSGETKELQDTLVVYDKACVELVNAKKKIQVLSTECSEEARKVEHALEWEEALKQTVADEKAKQVEALNQVERARRSFTREAYSRHKAEMATGMISEDRAQIVDAILSKSRTCRRYSKQDIQLATDNFSEARKIGEGGYGNVYRCTLDHTEVAVKVIQQDSIDRTDEFLKEVEILSQLRHPNLVLLVGFCPEIGCLVYEYLKNGSLEDQLFSSKAGRQPLHWFLRIQIIFEVSCGLAFLHARSPEPIVHRDLKPGNILLDGSYVGKIGDVGFAKLLSDLVPDWRTEYRETVVAGTLYYMDPEYQQTGTVRPKSDVFALGVIMLQLLTGRRPNGLIVGAEDAVRNGRLRDILDRSQSDWPVDEAEMFARLGLRCTALRCRDRPDLESEVLPELDEILHRVTSAVNLRNPKPSVPSHFICPITQELMEDPHVAADGHTYEHYAIRAWLKGHKTSPVTRSRLPNSSINPNHSLRAAIEQWRSQLPDQTNLRSGSQVHISP
Length751
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-0.320
Instability index54.12
Isoelectric point6.56
Molecular weight83019.93
Publications
PubMed=30683860

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22824
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.05|      13|      20|     190|     203|       1
---------------------------------------------------------------------------
  190-  203 (19.02/14.08)	EAIShEAFEQSHRS
  213-  225 (24.03/12.62)	EARS.DAFSHAHSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.66|      20|      38|     311|     330|       2
---------------------------------------------------------------------------
  292-  309 (16.66/ 8.28)	...EEARKVEhA.LEWEEALKQ
  311-  330 (30.63/22.07)	VADEKAKQVE.A.LNQVERARR
  349-  369 (26.37/17.87)	ISEDRAQIVD.AiLSKSRTCRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.36|      45|      52|     422|     470|       3
---------------------------------------------------------------------------
  422-  470 (63.42/57.50)	FLKeVEILSQLRhPNLVLLVGFCPEIgcLVYEYLKNGS.LEDQLFSSKAG
  477-  522 (75.94/49.59)	FLR.IQIIFEVS.CGLAFLHARSPEP..IVHRDLKPGNiLLDGSYVGKIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.29|      32|     699|      16|      50|       4
---------------------------------------------------------------------------
    5-   26 (16.92/ 7.80)	..............GPPPTVAV.....avavrPGGSGSRLA
   27-   64 (52.09/31.79)	ARWVAAGLP...DDGRAASVAVVHVIptlshvPSPTGERVP
   82-  107 (25.28/ 9.89)	ARAEEALLPfrhLNCRRANVTVETVV...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.56|      10|      31|     337|     346|       7
---------------------------------------------------------------------------
  337-  346 (18.27/12.32)	YSRHKAEMAT
  370-  379 (17.28/11.28)	YSKQDIQLAT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22824 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DAFSHAHSSHGASNVVPSSESSEQVASESSVANAAGAEGS
2) NHSLRAAIEQWRSQLPDQTNLRSGSQVHISP
217
721
256
751










Molecular Recognition Features






MoRF SequenceStartStop




1) LAARWV
25
30