<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22814

Description Mediator of RNA polymerase II transcription subunit 33A-like isoform X1
SequenceMAADAAELERRVMAAVKASAARGDPPLLQAAEAARCAREAAASGSASCGLALAEALVANLCFAHNTGSMWKLLDQAMSSRLVHPLHTLALLTPRVVPNRRQQPEAYRLYLELLGRYAVAPVYPERMERKSMLAKSIDDAMQLANRYGCQHLDFGHAVILFVLSLVEMLIDCILDDCGLLNISTHEHGNIYTKSMDFGGKGPHDRGDEHREHLRRKNILMSIEVVEKATANKIAQVFLRLVYLNTPENFNYLLRKLQLIGALESKNVLPAYNLLDSLTMNIQNVISTRYQLDRSRLLGVLLSTQPCSSSVFSIFGAGKGSCWVPFDMFMENAMDGRHLHAISSVEFLTELSKTLQVLNRATWQETFQALWISGLRLVQRGPEALEGPFPHLYSRLCMLLAIIPLSVATIVKEEVDKLDGGMVSAIKEELVSSLQILVQFSGLLSPPPATVHFANIAARKAAIVLSNLKSGNENLYGYSKDSSAIKAVGNMLHLIVEACIARNLIDTSAYFWPGYVVPLEASSQAQGSPWSSLTEGSPLMELKDALMVTPASSVAELEKLYSFAVSGSEEEKLAASKVLCGASLLRGWNIQEHVVQIVLKLLSSFLPLDSGSDGRYVQHMPMLHALISGISSVDAVHILSMYGLVPEVAAMLMPLCEIFGSLPPSDHRSCNFEKASVYSVFSSAFLSLLRLWKFHRPPIENALSRHGVFVRSELSLDFLLLLRNSRSALKNLSNVSKSSIFQLDPSLQKPVYIDSFPKLRAWYFQNQACIASTLSTVYNRPNVLHVANNILKIICHKVPKDGVLSVNPQSTSNSSVGSSPPPGVPEDMCQWPTLPAWDVLEAIPFVLEAVLTACAHGRLSSRDLITGLRDLADFLPASLAAIVSYFSAEITRGIWKPVMLNGTDWPSPAATLPVVESEINEVLALAGVNINISSRPRSVMPMLPLPIAALISLSITVKMEEFSHLHGIIGQGIEICATSSSWPSMQIIGALWSQKVRRWHDFIILACSQSPFTRDNTAVSQLIRSCFTSFLGPLVDGRSCYVANRGVADLLGKTLDERARLVVAPGFLYMRSCRLFPDNNFVCEEILKVVIERARALANDCSSERPGHLRSDCMPLSAASSLVEQISSLAATMLCHAGGLNLIRLLYEHILPTLLLSAGEDKLGSAGHVCSLFEGYALAYVLLWSGASIWGVGETSPAYASIYTSKRQRIVDRHLEFMAKVMEGNIVLGCGETTWRSYVLCFVGLLVDFVPAWILEVKLETLQKLASGLRKWHKGDLALSLLERGGNKAVTSVVESLLGYAGAQFSV
Length1305
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.07
Grand average of hydropathy0.200
Instability index48.55
Isoelectric point7.04
Molecular weight142906.24
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22814
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     659.82|     265|     372|     258|     539|       1
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  258-  424 (191.38/119.04)	..............................................................................................................................................................IGALESKNVLPAYN...........LLDSLtMNIQNVISTRYqLDRSRLLGVLLSTQPC.........................................SSSVFSIFGAGKGS...CWVPFDMFMENAMdGRH...LHAISSVEFLTEL..SKT.LQVLNRATWQETFQaLWISglrlVQRgPEALEGpFPHLYSRLCMLLAIIPLSVATIV.KEEVDKLDGGMVSAI
  425-  792 (366.46/199.26)	KEELVS.SLQILVQFSGLLSPPPAT....VHFANIAARKA..AI..VLSNLKSGNENLYGYSKDssAIKAVGNMLHLIvEACIARNLIDTSAYFWPGYVVPLeassQAQGSPWSSLTEGSPLMElkdalmvtpassvaeleklysfavsgseeeklaaSKVLCGASLLRGWNiqehvvqivlkLLSSF.LPLDSGSDGRY.VQHMPMLHALISGISSvdavhilsmyglvpevaamlmplceifgslppsdhrscnfeKASVYSVFSSAFLSllrLWKFHRPPIENAL.SRHgvfVRSELSLDFLLLLrnSRSaLKNLSNVSKSSIFQ.LDPS....LQK.PVYIDS.FPKLRAWYFQNQACIASTLSTVYnRPNVLHVANNILKII
  798-  914 (101.98/44.40)	KDGVLSvNPQSTSNSSVGSSPPPGVpedmCQWPTLPAWDVleAIpfVLEAVLTACAHGRLSSRD..LITGLRDLADFL.PASLAAIVSYFSAEITRGIWKPV....MLNGTDWPSPAATLPVVE.......................................................................................................................................................................................................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.85|      13|     210|    1022|    1034|       2
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 1022- 1034 (26.01/14.25)	RSCFTSFLGPLVD
 1234- 1246 (24.85/13.31)	RSYVLCFVGLLVD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.75|      20|      25|       2|      23|       4
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    2-   23 (28.00/28.89)	AADAAELERRvmAAVKASAARG
   30-   49 (35.75/28.03)	AAEAARCARE..AAASGSASCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.77|      53|     162|    1079|    1136|       5
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 1079- 1136 (76.07/54.07)	FVCEEILKVVIERARALAndcSSERPGHlRSDcMPLS.AASSLVEQISSLAATMLCHAG
 1247- 1300 (85.70/44.40)	FVPAWILEVKLETLQKLA...SGLRKWH.KGD.LALSlLERGGNKAVTSVVESLLGYAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.26|      24|      25|      75|      99|       6
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   75-   99 (37.40/26.54)	QAMSSRLVHPLHTLALLTPrVVPNR
  102-  125 (42.85/25.90)	QPEAYRLYLELLGRYAVAP.VYPER
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22814 with Med33 domain of Kingdom Viridiplantae
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