<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22808

Description Pre-mRNA-processing protein 40A
SequenceMQRIRFLLGASLPPRDCPKPHRDRELPTLADGYPTPDAPPCSAARCNMQPSGPPQPPRPPMMGSSSQPQNLGPPMPMQFRPVVPSQQPPQFMPPAAQQFRPVGQPMPGTNIGMPGQMPHFPQPGQHLSHSSQVPPASQGVPMAYQPGRPMSSAPMQPQQQAAYPGGHLPTMGAPMQPPSYTYQPTSIPPAVQPWGTAPGQSVPHVTPLVQPGHQLVPATTTLLSVNSSEPSSSDWQEHTAAEGKKYYYNKKTRQSSWEKPVELMTPLERADASTEWKEFTTPEGRKYYFNKVTKQSKWSIPDELKAARELAEKASNQQSDRETGITAASEPSTVPANQSSTAVGLITPSAHDASANSVPPGAGPSHNVDNTSSSSTVDKQNGGPNTAAFPVTTSTEVQLVATDAGTSRNNNENSSVTTAADTEDGTSAEDLEEAKKTMPVVGKINVSPLEEKTSEEEPVVYATKAEAKNAFKSLLESVNVESDWTWDQTMRVIINDKRYGALKTLGERKQAFNEYLNQRKKFEAEVKRIKQRKARDDFLAMLEECKELTSSTRWSKAILMFEDDERFKAVERPREREDLFENYLVELHKKEKTKALEEHRRHLAEYEAFLESCDFIKATTQWRKVQERLEDDERCSRLEKIDRLNIFQEYIRHLEKEEEEQKRIQKEQVRRQERKNRDAFRKMLEEHVTDGTITAKTRWRDYCSQIKDSQAYLAVASNTSGSTPKELFDDVIEELDKQYLDDKTRVKEVVKSGKIPMTTSWTLEEFQTAILDDDALKGISTINIKLIYDDQIERLKEKEQKDAKKRQRLGENFSDLLYSITEISASSTWDDSKQLFEDSQEFRALDSETYARELFEECVVHLKERLKEKERLREEEKIYIPSILDNVKFKSTAKREKEREEREKKKEKERKEKERKEKDREKEREKEKGKDRSRRDEMDIDGADVENHGSKDKKRDKEKKHKRRHHDTDDVSSERDDKDDAKKSRRHSSDRKKSRKV
Length997
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-1.103
Instability index53.01
Isoelectric point6.66
Molecular weight113851.97
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22808
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     149.39|      18|      19|      65|      82|       1
---------------------------------------------------------------------------
   33-   52 (24.30/ 8.94)	YP....TP.DAPPC...saaRCNM.QPSG
   53-   72 (29.03/12.13)	PP....QPP..RPP..mmgsSSQP.QNLG
   73-   92 (33.39/15.07)	PP....MPMQFRPV....vpSQQP.PQFM
   93-  103 (20.71/ 6.51)	PP....AAQQFRP..............VG
  113-  128 (20.10/ 6.10)	......MPGQM.PH......FPQPgQHLS
  134-  161 (21.86/ 7.29)	PPasqgVPMAYQPGrpmssaPMQP.QQQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.74|      20|      20|     894|     913|       2
---------------------------------------------------------------------------
  894-  913 (34.47/14.53)	KREKEREEREKKKE.....KERKEK
  954-  978 (24.27/ 8.26)	KRDKEKKHKRRHHDtddvsSERDDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     484.84|      65|      65|     537|     601|       3
---------------------------------------------------------------------------
  471-  533 (76.60/43.79)	.FKSLLESV....NVESDWTWD.....QTMRVIINDKRYGAL......KTLGERKQAFNEYLNQRKKFEaEVKRIKQ.RK
  537-  601 (104.07/62.12)	DFLAMLEEC...KELTSSTRWS.....KAILMFEDDERFKAV......ERPREREDLFENYLVELHKKE.KTKALEEHRR
  605-  663 (89.03/52.09)	EYEAFLESC...DFIKATTQWR.....KVQERLEDDERCSRL......EKI.DRLNIFQEYIRHLEKEE......EEQKR
  679-  745 (76.65/43.82)	AFRKMLEEHvtdGTITAKTRWR.....DYCSQIKDSQAYLAVasntsgSTPKE...LFDDVIEELDK.....QYLDDKTR
  751-  807 (56.62/30.46)	.......KS...GKIPMTTSWTleefqTAIL...DDDALKGI......STINIKL.IYDDQIERLKEKE.QKDA..KKRQ
  812-  873 (81.86/47.30)	NFSDLLYSI...TEISASSTWD.....DSKQLFEDSQEFRAL......DSETYARELFEECVVHL..KE.RLKEKERLR.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     192.24|      40|      40|     234|     273|       4
---------------------------------------------------------------------------
  234-  273 (77.24/47.50)	DWQEHT....AAEGKKYYYNKKTRQSSWEKPVELMTPLERAD.AS
  275-  315 (67.34/40.41)	EWKEFT....TPEGRKYYFNKVTKQSKWSIPDELKAARELAEkAS
  318-  354 (47.66/26.32)	QSDRETgitaASEPSTVPAN....QSS..TAVGLITPSAH.D.AS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.98|      16|      18|     176|     193|       5
---------------------------------------------------------------------------
  176-  193 (23.99/20.11)	QPPSYTYqPtSIPPAVQP
  196-  211 (27.99/14.24)	TAPGQSV.P.HVTPLVQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.82|      24|      24|     385|     408|       6
---------------------------------------------------------------------------
  385-  408 (39.84/30.88)	NTAAFPVTTSTEVQLV.ATDAGTSR
  410-  428 (29.46/20.35)	NNENSSVTTAAD......TEDGTSA
  445-  465 (20.52/11.28)	NVSPLEEKTSEEEPVVyATKA....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22808 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FKSTAKREKEREEREKKKEKERKEKERKEKDREKEREKEKGKDRSRRDEMDIDGADVENHGSKDKKRDKEKKHKRRHHDTDDVSSERDDKDDAKKSRRHSSDRKKSRKV
2) QRIRFLLGASLPPRDCPKPHRDRELPTLADGYPTPDAPPCSAARCNMQPSGPPQPPRPPMMGSSSQPQNLGPPMPMQFRPVVPSQQPPQFMPPAAQQFRPVGQPMPGTNIGMPGQMPHFPQPGQHLSHSSQVPPASQGVPMAYQPGRPMSSAPMQPQQQAAYPGGHLPTMGAPMQPPSYTYQPTSIPPAVQPWGTAPGQSVPHVTPLVQPGHQLVPATTTLLSVNSSEPSSSDWQEHTAAEGKKYYYN
3) SIPDELKAARELAEKASNQQSDRETGITAASEPSTVPANQSSTAVGLITPSAHDASANSVPPGAGPSHNVDNTSSSSTVDKQNGGPNTAAFPVTTSTEVQLVATDAGTSRNNNENSSVTTAADTEDGTSAEDLEEAKKTMPVVGKINVSPLEEKTSEEEPVVYA
889
2
299
997
249
462










Molecular Recognition Features






MoRF SequenceStartStop




1) GKKYYY
2) GRKYYFNK
3) HRDRELPTLADGY
4) KEKKHKRRHHDTDDVS
5) MQRIRFLLGASL
243
284
21
957
1
248
291
33
972
12