<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22806

Description U-box domain-containing protein 33-like
SequenceMGTGAQKWQAGPRQAKQPPAGRRGQPRQQAKRTRRSSCSLQRTGMATAATAGSSSPPTPHSPEPSLPGEKVYVAVGREVAESRATLLWALHKFPRGAGAGDASFVLLHVYSPPKLLPFLGARIPAAQVGEQELAAYKEMELQRVNDSLDQYLHLCAQGKIHAEKLVVESDDVAQGLVELISEHHVTALVMGAASDKHYTKKMKIPKSRKARLVELQADPSCKIWFICKGTLVCRRKAVQLSHEEMQECRQSSGVTHYSVDKSASLSEMWCVANTWLCKSIGEQRIERTTSDPFYISGKDNVEETYESYDNFQHILRELESVRQEAYEEKCRREKAERELFEALQKAQASENLYLREMKQKNELEEKLTTIMEEIESLTVRTDELCAKLQGEREQRMVLEKRGAYSDRIIKDLMLQRDKALRETEMLRAKKGESSATAEGMMHITELSYSEIKEATNDFDHSMKIGESVYGSVYRGFLRHTNVAIKKLNPETTQTQSQFSQEVEILSRVRHPNLVTLIGACKDAQALVYEYMPNGSLDDRLACKNNSKPLSWQLRTCIASNICSALIFLHSNKPHSIVHSDLKASNILLDGNNVAKLSGFGVSQILTDQFKATTTLYRYTHPKGSFVYIDPEYLISGDLTPQSDVYSFGIVLLRLLTGRSGFGLLKEVQQTMEKGCLQAILDSSAGEWPAMYAEQLAELGLRCCKIRRKNRPDLQTEAWTVLEPMFKSASTMLCSLSFKSVSEDLGGVPSYFICPILQDVMRDPLIAADGFTYEADAIREWLDNGHQTSLMTNLELPHRDLQSCSALCNSRMAADKWRLICLSSYQGT
Length827
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.07
Grand average of hydropathy-0.426
Instability index46.37
Isoelectric point7.50
Molecular weight92808.91
Publications
PubMed=30683860

Function

Annotated function Functions as an E3 ubiquitin ligase.
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP22806
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.99|      18|      20|     316|     333|       1
---------------------------------------------------------------------------
  316-  333 (30.58/19.24)	REL.ESV.RQEAYEEKCRRE
  337-  356 (17.41/ 7.84)	RELfEALqKAQASENLYLRE
  372-  387 (19.00/ 9.22)	EEI.ESL.TVRT.DELCAK.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.37|      16|      42|     218|     234|       4
---------------------------------------------------------------------------
  218-  234 (27.70/22.08)	DPS...CKIWFIcKGTLVCR
  260-  278 (27.67/15.87)	DKSaslSEMWCV.ANTWLCK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.82|      20|      41|       1|      26|       6
---------------------------------------------------------------------------
    1-   26 (28.32/30.86)	MGTGAqkwQAGprqAKQPPAGRRGQP
   45-   64 (38.50/20.92)	MATAA...TAG...SSSPPTPHSPEP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP22806 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MGTGAQKWQAGPRQAKQPPAGRRGQPRQQAKRTRRSSCSLQRTGMATAATAGSSSPPTPHSPEPSLPGEKVY
1
72

Molecular Recognition Features

MoRF SequenceStartStop
1) MGTGAQKWQAGPRQAKQPPAGRRG
1
24