<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22804

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMAMSAPPPASSWLEWTAEYTKAAQAESRPPPEWAARVAAASAAAGEGGDVPWSAGLAEVLARALLSGGAAAPAAAAAAAWKYAEAALAARLASPALLLAILSTRVIPQRFSRPMEYRLYLELLKRHGFSFHYQMKAANFRKIMGLIDGNLSLSKIFGISTCQPGVFVVHFVLCILWQLVDVVLDDEGLLELTPEKKAQWPTRPEDVSTFEGTFTEHRTEKIEKLQKMNTVTTMELIEHLLRNKVITRILSLARENMQSHWGAFTNRLHLLATNSSTLQNSAISLEPFQQLILGDCNVYGETKHNMRKRFHPIVASNPLSSPNGRCLGASYSALWIPIDMYLEDCLDGSIAATNSIEILSGLVKALQSVNRSTWHDAFLALWVASLRLVQREHTIRLVVKLLSPSDPIDYSGRESLLIKLGPMLNVILSGISAVDYAPIFSFHGLIPELAAALMAICEVFGCLSPSVSWTLRTGEEISAHTVFSNAFILLLRLWKFNHPPLEYCVMGDGAPVGSQLTPEYLLLLRNSQVLSPSSLAKQRSVQRQLQVPTSHPSCEHPIFMDSFPKLKLWYRQHQACLASTLSGLAHGTPVRNNVDSLLNLMFRKANKGGTSIGSISGSSSISNSSGPGGDDLHLWPQLPAWEILEAVPFVVDAALTACSHGRLFPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPASMNGSDWPSPSVNLSMVEEHIKKIVAATGVDVPRLVTGGSSSGTLPLPLAAFVSLTITYKLDKASERFLNLAGPALENLAASCPWPSMAIVAALWTQKVKRWSDFLVFSASRTVFHHNNDAVIQLLRSCFAATLGMSSTSVCSCGGVASLLGHGYCPGGFSPVAPGILYLRIFRCIKDCSILAEDILYLLMLSVKDIAETTVPRQLSDKLKTTKYGTRHGRVSLSAAMTQVKVAASLGATLVWLSGGTALVQSLIQEMLPSWFLSVQNLDQGGTRGGMVYKLGGHALAYLAVYSGMFAWGIDPTPVSRRRERVTRSHLEFLASALDGKISLGCDPSLWRAYVAGFLGLVVECTPCWVQEVELRVLKRLSSGLRQWGEDELAVALLRRAGPEAMGTAAELILGSEW
Length1106
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.08
Grand average of hydropathy0.166
Instability index42.62
Isoelectric point8.43
Molecular weight120204.74
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22804
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     269.73|      67|      73|     436|     508|       1
---------------------------------------------------------------------------
  128-  176 (48.42/20.29)	.....FSFHyqmkaanfrkimGLI.DGNLSLSKIFGISTC.QP.......GV.................FVVHFVLCI.LW..........
  434-  503 (122.06/74.76)	DYAPIFSFH............GLIPELAAALMAICEVFGCLSP.......SVSWTLR..TGEEISAHTVFSNAFILLLRLWKFNHPPleyC
  507-  575 (99.25/48.69)	DGAPVGS..............QLTPEY.LLLLRNSQV...LSPsslakqrSVQRQLQvpTSHPSCEHPIFMDSFP.KLKLWYRQHQA...C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.99|      22|      67|     664|     687|       2
---------------------------------------------------------------------------
  664-  687 (29.99/28.09)	PReLATGLKDlADFLPASLATIVS
  734-  755 (40.01/26.40)	PR.LVTGGSS.SGTLPLPLAAFVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.53|      18|      20|       4|      23|       3
---------------------------------------------------------------------------
    4-   23 (31.38/21.81)	SAPPPasSWLEWTAEYTKAA
   27-   44 (33.15/17.18)	SRPPP..EWAARVAAASAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.97|      13|      73|     995|    1007|       4
---------------------------------------------------------------------------
  995- 1007 (27.36/13.77)	SGMFAWGIDPTPV
 1071- 1083 (24.61/11.72)	SGLRQWGEDELAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     194.34|      46|      46|     290|     335|       5
---------------------------------------------------------------------------
  253-  286 (44.46/28.62)	............RENMQSHWGAFTNRLHLLATNSSTLQNSAISLEP
  290-  335 (79.42/58.05)	LILGDCNVYGETKHNMRKRFHPIVASNPLSSPNGRCLGASYSALWI
  339-  382 (70.46/50.50)	MYLEDCLDGSIAATNSIEILSGLV..KALQSVNRSTWHDAFLALWV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.41|      25|      75|     700|     724|       7
---------------------------------------------------------------------------
  700-  724 (45.91/23.60)	PASMN...GSDWPSPSVNLSMVEEHIKK
  775-  802 (41.50/20.67)	PALENlaaSCPWPSMAIVAALWTQKVKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.75|      20|      20|      54|      73|      10
---------------------------------------------------------------------------
   54-   73 (31.78/16.68)	AGLAE.VLARALLSGGAAAPA
   75-   95 (25.98/12.27)	AAAAAwKYAEAALAARLASPA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22804 with Med33 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) SSWLEWTAEYTKAAQ
10
24