<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22803

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAAAAAERQLVVAVEGTAALGPYWSTIVGDYVEKIVRSFCTNEVLGQKLAGAPPELALVVFHTHGPYSAFGVQRSGWTKDIDAFLSWLSGISFSGGGFSEASTCEGLAEALTILQGSPNTTQSHQNHEAQKHCILVAASNPYPLPTPVYCIPTQSTDHKENTESSKEPSIADAEAVAKSFAQCSVSLSVISPKQLPTLKAIYNAGKRNPRAADPSVDHAKNPHFLVLLSENFMEARTALSRPLHGNLAPNQTVTKMDTAPAVTMAGPTSNANPSVNGPMMGRQPVGVGGVSTATVKLEPATIPPMVSAPAFSHVTPISNVASQGISALQTSSPSLISQEANIANDNVQEHKPIIHPVQQPVRPGGHGSLLNNLSQVRLMNSTSLGGGATSMGLPNIGATPIQVHMSNMISSGMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTSTVSGNSNIAVSSSLPSIQSSMSMGQSVQPVAQGGLMAGSQLGQGGSAANQNVSGLGPTAISSALAMMPTPGMAQSTGVNSLGVTNNSAMNMPIGQHPNAQQPPPKYVKIWEGTLSGQRQGQPVFICKLEGYRSGTASETLAADWPETMQIVRLIAQEHMNNKQYVGKADFLVFRTLNQHGFLGQLQEKKLCAVIQLPSQTLLLSMSDKAGRLIGMLFPGVILILAK
Length675
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.04
Grand average of hydropathy-0.072
Instability index42.21
Isoelectric point8.11
Molecular weight70387.29
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22803
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     215.76|      47|      47|     417|     463|       1
---------------------------------------------------------------------------
  321-  361 (33.04/ 9.49)	ASqgiSALQT..SSPS.LISQEANIAndnVQE...................................H.KPIihPVQQPV
  389-  436 (72.90/29.16)	TS...MGLPNIGATPI.QVHM.SNM....ISSgmtST...........PSV.......ISSMS.GP.G.QPI..STQQMV
  437-  485 (67.85/26.67)	QS...TALGSFGSNTS.TVSGNSNIA...VSS...SL...........PSI.......QSSMSmGQ.SvQPV..AQGGLM
  486-  550 (41.97/13.90)	AG...SQLGQGGSAANqNVSGLGPTA...ISS...ALammptpgmaqsTGVnslgvtnNSAMN.MPiG.QHP..NAQQ..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     186.10|      58|     561|       7|      65|       2
---------------------------------------------------------------------------
    7-   65 (95.13/65.11)	ERQ....LVVAVEGTAAlGPYWSTIVGDYVE..KIVRSFCTNEVLGQKLAGAPPELALVVFHTHG
  566-  629 (90.97/57.91)	QRQgqpvFICKLEGYRS.GTASETLAADWPEtmQIVRLIAQEHMNNKQYVGKADFLVFRTLNQHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.02|      22|      88|     175|     224|       4
---------------------------------------------------------------------------
  163-  188 (29.32/57.93)	ESSKEPSIadaeAVAKSFAQCSVSLS
  217-  240 (32.70/ 6.25)	DHAKNPHF..lvLLSENFMEARTALS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.50|      19|      40|     252|     276|       5
---------------------------------------------------------------------------
  252-  270 (34.45/30.92)	TVTKMDTAPAVTMAGPTSN
  301-  319 (36.05/17.08)	TIPPMVSAPAFSHVTPISN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22803 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALSRPLHGNLAPNQTVTKMDTAPAVTMAGPTSNANPSVNGPMMGRQPVGVGGVSTAT
2) GMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSN
3) LQTSSPSLISQEANIANDNVQEHKPIIHPVQQPVRPGGHGSLLNNLSQV
4) QSSMSMGQSVQPVAQGGLMAGSQLGQGGSAANQNVSG
5) VTNNSAMNMPIGQHPNAQQPPPKYVKIWEG
238
412
328
467
532
294
447
376
503
561










Molecular Recognition Features






MoRF SequenceStartStop




1) KYVKIW
554
559