<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22800

Description ATP-dependent DNA helicase Q-like 4A
SequenceMAMRAGSCGLGAARRRGCLRTGGGRASDALSRARPQAVRRARRSGPRAELGRGWGGSRRTRWGEAMVGKHGRGRRVRWAARTDRPRQGGGPRRNKPSVGLIRTEKLPRVNWPNHADAIQSSSRKDDFLSSSFLFSLPTQRPNPEANSETMLSLRYSACKIQGPERLQVPWIEKAWRSLCNTQVPYKSYLRPGLSAKVKEHDRDHARTYGEGLCNINKIATVPGNRILSQESMHQPPESGYPANNGNHQPAGIHSSPRTHLSNHVLQADIIRTTNWSSFSKTDAELNWSTPAAYNMCTDEKLDAMDDDDILASIDVDRIVMEHYQATSTPRGLASDNMSTPSGNKCNFNGLEENNLPEELSVLCSHHSKLAFCPEAMSHLREMKDELIEVANKLLDGDCEFNPEHSEELRKRRVHLKRQVELLGEYLARSTQDEDRQRSHSMASTTAVQGHQPPMTPRSTFVMDADRFQSQVYIRNGPGANDLCYSSVPYSYMDNLNTPVNSVRREYTPRIIDINYTEGSNDKNWSSRNFPWTKDLEAKNKKVFGNRSFRPNQREIINATMSGNDVFVLMPTGGGKSLTYQLPALIGEGITLVVCPLVSLIQDQIMHLLQAEIPATYLSASMEWSKQQEILRELMSHTCHYKLLYVTPEKIAKSDALLRLLEHMYSRGHLSRIVIDEAHCVSQWGHDFRPDYQDLGILKQKFPNTPVLALTATATASVKEDVVQALGLANCIVFRQSFNRPNLRYYLRPKTKKCLEDINGFIRKNHPNDCGIIYCLSRMDCEKVAEKLRDSGHKAAHYHGSMDPADRENVQEQWSMDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCVLYYQYSDYIRLKHMVTQGVVEQTAAASRRGSLSSQGQALETHKDNLLRMVSYCENDVDCRRLLQLIHFGEMFDPSHCAKTCDNCLKELRWVEKDVTNIARQLVELVKMTKQSCSSSHILEVYRGSVSQNVRKHRHETLSLHGAGKHLTKGEAARILRHLVTERILTEDVKKSDSYGSVSSVLMVNYTEAADLFSGKRSIILKVPTPENASKMGKIDESSFQQTNKTAQQHNEVDENLASVLYKTLHSLRRQILKGCGEGCRAYHIFRNETLKEISSRVPRTKEELLEINGIGKEKLNKYGDLVLATIEDFLSKNPNPRKNSSGGSSGSNEHTEAAKKRRGFTAGNASSNGGEDDFEERTVQSKKRPAKTRSTKQGVSDAASMVHGARCMDADLDGVEALDDELCSVQKPVASGRVLPKWAPAKAKSSSVPPSNLFQEFGYVK
Length1310
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-0.638
Instability index52.12
Isoelectric point9.04
Molecular weight146927.53
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22800
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.62|      14|      16|      39|      52|       1
---------------------------------------------------------------------------
   39-   52 (26.25/12.86)	RRARRSGPRAELGR
   58-   69 (20.25/ 8.19)	RRTRWG..EAMVGK
   89-  102 (21.11/ 8.86)	GGPRRNKPSVGLIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.79|      13|      50|     283|     296|       2
---------------------------------------------------------------------------
  283-  296 (22.59/18.64)	AELNWSTPAAyNMC
  333-  345 (26.20/15.65)	ASDNMSTPSG.NKC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.03|      38|      50|     445|     482|       3
---------------------------------------------------------------------------
  429-  457 (38.97/22.09)	ST..QDEDRQRSH.....................smastTAVQGHQPPMTPR
  458-  509 (57.83/36.72)	STFVMDADRFQSQVYIRNGPGANDLcyssvpysymdnlnTPVNSVRREYTPR
  670-  694 (36.22/19.96)	SRIVIDEAHCVSQWGHDFRPDYQDL...........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     469.16|     128|     144|     961|    1096|       5
---------------------------------------------------------------------------
  835-  954 (103.12/67.67)	........................................DVRFVIHHSLPKSIEGYHQECGRAGR.dgqpsscvlyyqysdyirLKHMVTQGVV.EQ..TAAASRRGSLSSqgqalethkdnlLRMVSYCE.NDV.DCRR..LLQL......IHFGEMfD...PSHCAKTcDNCLK
  961- 1096 (192.20/162.75)	KDVTNIARQlveLVKMTKQSCSSSHIlevYRG....SVSQNVRKHRHETLSLHGAGKHLTKGEAARI..................LRHLVTERILTED..VKKSDSYGSVSS............VLMVNYTEAADLfSGKRSIILKVpTPENASKMGKI.D...ESSFQQT.NKTAQ
 1111- 1236 (173.85/123.31)	KTLHSLRRQ...ILKGCGEGCRAYHI...FRNetlkEISSRVPRTKEELLEINGIGKEKLNKYGDLV..................LATI..EDFLSKNpnPRKNSSGGSSGS...............NEHTEAA...KKRRGF.....TAGNASSNGGE.DdfeERTVQSK.KRPAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.60|      13|     152|     107|     119|      12
---------------------------------------------------------------------------
  107-  119 (27.50/19.34)	PRVNWPNH...ADAIQ
  256-  271 (20.10/11.90)	PRTHLSNHvlqADIIR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22800 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EYLARSTQDEDRQRSHSMASTTAVQGHQPPMTPRSTFV
2) FLSKNPNPRKNSSGGSSGSNEHTEAAKKRRGFTAGNASSNGGEDDFEERTVQSKKRPAKTRSTKQGVSDAASMVH
3) LGAARRRGCLRTGGGRASDALSRARPQAVRRARRSGPRAELGRGWGGSRRTRWGEAMVGKHGRGRRVRWAARTDRPRQGGGPRRNKPSVGLIRTEKL
4) NRILSQESMHQPPESGYPANNGNHQPAGIHSSPRT
424
1178
10
224
461
1252
106
258










Molecular Recognition Features






MoRF SequenceStartStop




1) LFQEFGYVK
2) RVLPKWAPAKAK
3) RWGEAMVGK
1302
1282
61
1310
1293
69