<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22774

Description U-box domain-containing protein 35-like
SequenceMEIEEAAGEMEEMEAPAVSTVAVAISGSRSSRHALKWALDKFVPEGRVLFRILHVRPAITMVPTPMGNFIPISQVREDVASAYRKEAEWQASNMLLPFKKMCAQKKVEAEAVLLESDDVAAAISEEIGKFNISKLVLGSSSKNIFRRKLKGSKTATKISESIPSFCTAYVISKGKLSFVRSATSDIVETPQSIYSSTVSSPSSRSLSSCAPSEWGDTYGTENVSFHQPSLPLQRDQALAIINKLSHSHRRAGSGSVASEVSCNDGPGLTSSHSIASEMQFSSGSSGNSMHKSFHRDNLPDNSDHALVSEISETVHHSNDQDDLKLQIERLRVKLQHLHKLHECAQHESFDTTQELKKLRTQHIEDEIKLKEIQLTEGRVRRLVRKQEMEEHEAGKEAEFKQHSYEIEEKHSYNGQANENKTGQKIAGCCFDKYNRYKWEEIQASTSSFSSALMIGKGSYGTVYKAKFHHTIAAVKVLNSPEGCGSQQLQQELEVLGKIRHPHLLMMLGACPEHGCLVYEYMENGSLDDMLQRRNNTPPLTWFDRFRITWEVATALMFLHSSKPEPIIHRDLKPANILLDRNLVSKIGDVGLSTLLPSMGQYLSTMIKNTAPVGTLCYIDPEYQRTGVLSMKSDVYALGIVILQLLTARSPMGLAHVVETALEDGCFIDILDASAGQWPLNETQELAALALKCSEMRRKDRPDLNEHVLPTLERLKDVATKARESVLQGHTAPPSHFICPILQEVMLDPYVASDGYTYDRKAIELWLSSNDTSPMTNLHLPNKSLIPNHSLRSAIMDWRSKSK
Length802
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-0.389
Instability index49.63
Isoelectric point6.49
Molecular weight89434.76
Publications
PubMed=30683860

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22774
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.23|      27|      48|     322|     349|       1
---------------------------------------------------------------------------
  322-  349 (43.28/42.73)	DLKLQIERLR..VKLQHLHKlHECAQHESF
  371-  399 (38.94/31.76)	EIQLTEGRVRrlVRKQEMEE.HEAGKEAEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.04|      46|      48|     572|     619|       2
---------------------------------------------------------------------------
  572-  619 (73.14/64.04)	KPANILLDRNLVSKIGDVGLSTLLPSMGQYLSTMIKNTAPVGtlCYID
  623-  668 (75.90/59.35)	QRTGVLSMKSDVYALGIVILQLLTARSPMGLAHVVETALEDG..CFID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     214.39|      63|      67|     175|     240|       4
---------------------------------------------------------------------------
  175-  238 (106.94/75.64)	KLSFV.RSATSDIVETPQSIYSSTvSSPSSRSLSSCAPSEWGDTYGTENVSFHQPSLPLQRDQAL
  243-  306 (107.45/66.02)	KLSHShRRAGSGSVASEVSCNDGP.GLTSSHSIASEMQFSSGSSGNSMHKSFHRDNLPDNSDHAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.96|      11|     281|     164|     174|       8
---------------------------------------------------------------------------
  164-  174 (21.59/14.64)	SFCTAYVISKG
  447-  457 (20.37/13.41)	SFSSALMIGKG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22774 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RRLVRKQEMEEHEAGKEAEFKQHSYEIEEKHSYNGQAN
2) SHSIASEMQFSSGSSGNSMHKSFHRDNLPDNSDHALVSEISETVHHSNDQDDLKLQIE
380
271
417
328










Molecular Recognition Features






MoRF SequenceStartStop




1) SAIMDWRSK
792
800