<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22709
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MAAMGDDLRLDLDKLPIKRLEAIDEAGNEHYPPEEQRLAARVDFSWVVERDAKKAKKAAAEDVAHKAWPWQGLHESLQLAQQELTVVLDLISTVEANDTVAFAAISKPKPLVDEVLVDMALSAATKLQRLRHLGRYFKQSAKTMEQQFQKEAKFYGSLIRLQQNWKVKRQRGNAPGSNSFMFDVVDTSQLDTEVMPRLSSLSFVPIDQDSSGTLSVQVPQKSCRFLSLQFRGDSASGVESYTCKTKGVSSTTSSAAEDDASENDDVNKSVKQAHSTLRNIHKSIFEEQVFDMMIRETFVQTQGVNVTGMREDFLQLAIGQENLLCLSLANSGQDSDSEMAGHEEHTNSEANLVLATTNGKQEPLKSNPSGFLNPKSLEIYLLHMFHDNILKKVREKYRNIVRYQSPAHTAEPAGDECGSLGHFCMTVAHKIFSNKVQLELECVVSRVPYLHLQSLPTWHSRTSSWSICLSVPQPILAADRLMKPSDNGEPEYKSSRTQFNMKIVLKDGQISLLGEGSPSIAGSLTRKPSDGYLINSYSCDLEDLPTMVLQQVASQVINWLHEEAQVLGVSVTRDFLGLYFDLDHGDTTLGLVAQVDPDDAYGCVSWYLTVDHPAEEGKVPAVDDPWAEKCRFLGYLSLEVLHATLMDLINLCDNRRPPAEMMVEVCSSAGFVSYCAH |
Length | 677 |
Position | Head |
Organism | Triticum aestivum (Wheat) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade>
Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.323 |
Instability index | 41.43 |
Isoelectric point | 5.28 |
Molecular weight | 75322.36 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP22709
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 109.53| 33| 42| 361| 401| 1
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361- 394 (53.16/41.60) QEPLKS.NPSGfLNPKSLEIYLLHMFHDNILKKVR
404- 437 (56.38/26.45) QSPAHTaEPAG.DECGSLGHFCMTVAHKIFSNKVQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 63.66| 18| 42| 469| 486| 2
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469- 486 (31.98/21.08) LSVPQPILAADRLMKPSD
513- 530 (31.68/20.81) LGEGSPSIAGSLTRKPSD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 220.82| 75| 555| 11| 91| 4
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11- 91 (122.33/93.68) DLDKLPIKRLEAIDEAGNEHYPPEEQRLAARV..DF.............................SW..VVERDAKKAKKAAAEDvahkawPWQGLHESLQ.LAQQEL.TVVLDLI
540- 649 (98.49/63.20) DLEDLPTMVLQQVASQVINWLHEEAQVLGVSVtrDFlglyfdldhgdttlglvaqvdpddaygcvSWylTVDHPAEEGKVPAVDD......PWAEKCRFLGyLSLEVLhATLMDLI
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