<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22535

Description ATP-dependent DNA helicase
SequenceMEDEENIEEELLLVESQLNGLQDKIKTLLDQQEELYERQAQLKAMLEISKTSRDASNSAPSVALEDWSGKFSWDSQADDTRFNVFGISSYRSNQREIINSIMSGKDVLVIMAAGGGKSLCYQLPAVLRDGITLVVSPLLSLIQDQVMGLAALGIPAHMLTSTTNKEIEKFIYKALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLVAIDEAHCCSQWGHDFRPDYKNLGILKIQFPSVPMIALTATATSKVQMDLIEMLHIPRSVKFVSTVNRPNLFYRVYEKSSVGKVVIDEIANFISESYPNNESGIVYCFSRKECEQVAKELRGRGISADYYHADMDVVAREKVHMRWSKSKSQVIVGTVAFGMGINKPDVRFVVHHSLSKSMETYYQESGRAGRDGLPSECVLYYRPGDVPRQSSMVFYENCGLQNLYDIARYCQSKKNCRRGAFFQHFGEAVQECNGMCDNCVSSIELKDIDATYHTKITVSLLQEMQQNDQRATLLQLVDKFKTKWKHSGCSNEAVDLKKEEIEQLIVQLILDRVLKEEFQHTAYTTNAYVVLGPLWKPALQGNRPVKLTSAIHSQDSGDRFKSAKRNQMSNLEAKLDDLRRTISSRNGGIFPHAVLSTEQISLLNCHTPTTIAELEKLIGKVKTDKYGSDIIEVMWSETGSGKDSGDGAKRQKKDKGVVFVESGEEEG
Length703
PositionUnknown
OrganismTriticum aestivum (Wheat)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
Aromaticity0.07
Grand average of hydropathy-0.385
Instability index42.43
Isoelectric point6.53
Molecular weight79050.30
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
DNA helicase activity	GO:0003678	IEA:UniProtKB-EC
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP22535
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.49|      13|      30|     348|     362|       1
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  348-  362 (21.25/17.82)	DVvaREKVHMRWSKS
  381-  393 (24.24/13.85)	DV..RFVVHHSLSKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.26|      14|      30|     168|     182|       2
---------------------------------------------------------------------------
  168-  182 (20.55/16.19)	EKFIYKaLEK..GEGEL
  196-  211 (20.71/11.25)	KRFMSK.LEKchHAGRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.73|      19|      30|     430|     448|       3
---------------------------------------------------------------------------
  430-  448 (36.63/21.36)	FYENCG..LQNLYDIARYCQS
  457-  477 (34.11/19.46)	FFQHFGeaVQECNGMCDNCVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.36|      46|      85|     556|     603|       4
---------------------------------------------------------------------------
  556-  603 (71.34/44.48)	HTAyTTNAYV..VLGPLwKPALQGNRPVK.LTSAIHS.QDSGDRFKSAKRNQ
  642-  691 (67.02/33.23)	HTP.TTIAELekLIGKV.KTDKYGSDIIEvMWSETGSgKDSGDGAKRQKKDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.44|      26|      30|     282|     310|       5
---------------------------------------------------------------------------
  284-  310 (36.93/34.37)	LFYrVYEKSSVGKVVIDEIANFISESY
  317-  342 (43.52/26.00)	IVY.CFSRKECEQVAKELRGRGISADY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP22535 with Med34 domain of Kingdom Viridiplantae

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