<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22425

Description Uncharacterized protein
SequenceMGDGRGGGSNRPAWLQQYELVGKIGEGTYGLVFLARLKPTHPQAAGRRGSPIAIKKFKQSNEGDGVSPTAIREIMLLREINHENVVKLVNVHINHADMSLYLAFDYAEHDLYEVIRHHREKLNLSINQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEHGIIKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGVEAKATPNPFQLDQLDKIFKVLGHPTVEKWPTLANLPCWQNDQQHIQGHKYENTGLHTIVHLPQKGPAFDLLSRMLEYDPRKRITAAQALEHEYFRMDPLPGRNALVPSQPGEKIVTYPVRPVDTSTDFEGTTSLQPTQPPSGNGPPGGQPVPRQIPRQMQQPMGGMQRMPPGANMGAFGAAPQAGMVGMNPGNIPMQRGAGGQSHPHQLRRKADQGMGMQNPGYPQQKRRF
Length470
PositionKinase
OrganismTriticum aestivum (Wheat)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
Aromaticity0.07
Grand average of hydropathy-0.462
Instability index34.98
Isoelectric point9.32
Molecular weight52349.48
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22425
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.23|      29|      29|     340|     368|       1
---------------------------------------------------------------------------
  311-  350 (37.32/21.14)	SRMLEYdPRKRITAAQALEheyfrmdplpGRNALVPSQP..G
  351-  381 (45.91/27.61)	EKIVTY.PVRPVDTSTDFE..........GTTSLQPTQPpsG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.01|      14|      29|     424|     437|       2
---------------------------------------------------------------------------
  404-  414 (22.86/ 7.60)	GMQRM.PPGA...NM
  424-  437 (31.52/12.82)	GMVGM.NPGNIPMQR
  455-  467 (23.64/ 8.07)	GM.GMqNPG.YPQQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.19|      39|     117|     149|     192|       3
---------------------------------------------------------------------------
  149-  190 (59.07/48.81)	WIIHRDLKPSNILvMGEGEEHGIIKIADFGLarIYQA..PLKPL
  195-  235 (63.12/35.43)	VVVTIWYRAPELL.LGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22425 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDPLPGRNALVPSQPGEKIVTYPVRPVDTSTDFEGTTSLQPTQPPSGNGPPGGQPVPRQIPRQMQQPMGGMQRMPPGANMGAFGAAPQAGMVGMNPGNIPMQRGAGGQSHPHQLRRKADQGMGMQNPGYPQQKRRF
335
470










Molecular Recognition Features






MoRF SequenceStartStop




1) MQNPGYPQQKRRF
2) SHPHQLRRKADQ
458
443
470
454