<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22397

Description "Transcription elongation factor A (SII), 3"
SequenceMTREEDLIRIAKKLDKMVSRNNTDGAIDLLKELKSFNMTLKLLQETRIGMSVNNIRKHCRDEEVIALAKVLIKEWKRLLDSGNSHSEKVDELKNGLDARKPAAATNSCSSEPQSRKEPPDPNAPLPPLPLHLHPPAAPPKRTSVDGGKDRESSRKPSSDSKPLPQKKPADCVKKDRKDSDDGKASKKLSEDTKRERKDSSDSKPPSTKKPTIEVKKEKHRKDSSELKPSQPAKGHSTDSKSVRRESLGSKPLGQPQRKPSTDSLDRKGKTEAPRTPTTPTSPLSPSFSSPGGPLSPHLATGDSVRDKCIEMLTAALRTDNDYKDFGANCDGMAAEIEDHIYQEIRATDMKYKNRVRSRISNLKDPKNPGLRRNVLAGSIELSRIASMSAEEMASDELKQLRNVLTQEAIREHQMAKTGGTTTDLLQCGKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length465
PositionUnknown
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.02
Grand average of hydropathy-1.034
Instability index56.11
Isoelectric point9.44
Molecular weight51679.07
Publications
PubMed=23542700

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22397
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.54|      22|      22|     178|     199|       1
---------------------------------------------------------------------------
  156-  176 (23.04/ 8.32)	PSSDSKplPQKKPADCVKKDR...
  178-  199 (34.74/16.32)	DSDDGK..ASKKLSEDTKRERKDS
  225-  246 (31.75/14.28)	ELKPSQ..PAKGHSTDSKSVRRES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.23|      24|     119|     125|     154|       3
---------------------------------------------------------------------------
   96-  119 (41.73/24.23)	LDARKPAAATNSCS.SEPQSRKEPP
  130-  154 (38.49/18.58)	LHLHPPAAPPKRTSvDGGKDRESSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.82|      14|      27|     422|     435|       4
---------------------------------------------------------------------------
  422-  435 (27.63/17.69)	TDLLQCGKC..KKKNC
  450-  465 (25.20/15.54)	TTFVLCNECgnRWKFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.59|      15|      16|     247|     261|       5
---------------------------------------------------------------------------
  247-  261 (27.41/12.26)	LGSKPLGQPQRKPST
  264-  278 (23.17/ 9.34)	LDRKGKTEAPRTPTT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.28|      32|      56|       3|      34|       6
---------------------------------------------------------------------------
    3-   34 (51.33/37.75)	REEDLIRIAKKLDKMVSR..NNTDGAIDLLKELK
   60-   93 (47.95/34.77)	RDEEVIALAKVLIKEWKRllDSGNSHSEKVDELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.20|      13|      16|     294|     306|       7
---------------------------------------------------------------------------
  294-  306 (22.48/12.81)	LSPHLATGDSVRD
  312-  324 (21.71/12.15)	LTAALRTDNDYKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22397 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GNSHSEKVDELKNGLDARKPAAATNSCSSEPQSRKEPPDPNAPLPPLPLHLHPPAAPPKRTSVDGGKDRESSRKPSSDSKPLPQKKPADCVKKDRKDSDDGKASKKLSEDTKRERKDSSDSKPPSTKKPTIEVKKEKHRKDSSELKPSQPAKGHSTDSKSVRRESLGSKPLGQPQRKPSTDSLDRKGKTEAPRTPTTPTSPLSPSFSSPGGPLSPHLATGDSVRDKCIEMLT
82
313










Molecular Recognition Features






MoRF SequenceStartStop




NANANA