<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22390

Description Uncharacterized protein
SequenceMEPSTKPGPSQVADVVFVIEGTANLGPYFESLRKNYILPAIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAFEFVSWIDSIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGFTADNLVKIIRDRGIHFSVVAPRKLPALRALFEWASPVTGAVEPHPDYSQDPFHMVLVRGISLPVSAGGGQPHKPVLPPQPLPGSQSVVGPSQAPPPINPAHSYQNQPPLTPAQVAAQMAVDAANNQKNRFTGITGGQFQNQSISSVPGSKHGPPSLPTVTTVNQPMTQQVPPNSQQTVPPPGQLVVSQPVQPQPQPNQPPAPSAQPNIASVPPGQVNANQMGQPQGVANKVVAWTGVLEWQEKPKASSMDSTKLTRSLPCQVYVNQGENLNTDQWPQKLIMQLIPQQLLTTLGHLFRNSRMVQFLFTSKDMDSLRGLYRIMANGFAGCVHFPHTTSPCEVRVLMLLYSSKKKIFMGLIPNDQSGFVNGIRQVITNHKQVQQHRAQLGGASVSMQPNQVPTNQNFLNRPPGPIPVSHGNVQQQMTMRAAGPTNQQPPVSGAPPNQVAQGGQTQPQGSILRLPNPGANPQLRSLLLSQQQPQGGVSHMPNMMSHQALGQQMVHPAPGGGPQIQNQWRQPMSGQQTHNCSQQDEGKMTEYLWEKADSSLFPTWLLQTSQQQLATICFVQDPFLILLLFFFNSLKNILQMILSKSTFYSFGSLFDRVLRPGKKIFDYLLEFSHNISTIFTRMF
Length790
PositionUnknown
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.08
Grand average of hydropathy-0.297
Instability index49.90
Isoelectric point8.77
Molecular weight86219.35
Publications
PubMed=23542700

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22390
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.63|      22|      23|     595|     616|       1
---------------------------------------------------------------------------
  330-  357 (30.52/ 7.29)	QvPPNSQqtvPPPGQlvVSQPVQPQPQP
  595-  616 (47.11/15.18)	Q.PPVSG...APPNQ..VAQGGQTQPQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     288.02|      47|      91|     548|     594|       2
---------------------------------------------------------------------------
  174-  209 (44.91/13.48)	.GIHFSvVAPRKLPALRALF...EWAS...............PVT.GAVEPH.........P..DYS
  219-  254 (55.69/18.43)	RGISLP.VSAGGGQPHKPVL.....PP.Q.....P......LPGSQSVV...........GP..SQA
  255-  302 (50.00/15.82)	P........PPINPA.HSYQ...NQPPlT.....PaqvaaqMAVDAANNQKNRFTGI..TGGqfQNQ
  548-  594 (84.26/31.56)	GGASVS.MQPNQVPTNQNFL...NRPP.G.....P......IPVSHGNVQQQMTMRA..AGP..TNQ
  622-  674 (53.17/17.28)	P.......NPGANPQLRSLLlsqQQPQ.GgvshmP......NMMSHQALGQQMVHPApgGGPqiQNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.82|      11|      23|     358|     368|       3
---------------------------------------------------------------------------
  358-  368 (21.83/ 9.49)	NQPPAPSAQPN
  380-  390 (20.99/ 8.78)	NQMGQPQGVAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.36|      21|      24|     450|     473|       4
---------------------------------------------------------------------------
  450-  470 (36.70/29.16)	LTTLGHLFRNS................RMVQFLFTSK
  475-  511 (25.66/10.35)	LRGLYRIMANGfagcvhfphttspcevRVLMLLYSSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.93|      22|      24|     742|     765|       5
---------------------------------------------------------------------------
  742-  765 (31.29/28.47)	KNILQMILSKStfYSFGSLFDRVL
  769-  790 (37.64/26.24)	KKIFDYLLEFS..HNISTIFTRMF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22390 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGGQPHKPVLPPQPLPGSQSVVGPSQAPPPINPAHSYQNQPPLTPAQVAAQMAVDAANNQKNRFTGITGGQFQNQSISSVPGSKHGPPSLPTVTTVNQPMTQQVPPNSQQTVPPPGQLVVSQPVQPQPQPNQPPAPSAQPNIASVPPGQVNANQMGQPQ
2) HKQVQQHRAQLGGASVSMQPNQVPTNQNFLNRPPGPIPVSHGNVQQQMTMRAAGPTNQQPPVSGAPPNQVAQGGQTQPQGSILRLPNPGANPQLRSLLLSQQQPQGGVSHMPNMMSHQALGQQMVHPAPGGGPQIQNQWRQPMSGQQTHNCS
228
537
386
688










Molecular Recognition Features






MoRF SequenceStartStop




NANANA