<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22384

Description Uncharacterized protein
SequenceMTTVSATPQQMKDRLLQAIDSQSNIRDMAVVLEVIACLEKYPITKEALEETRLGKLINDVRKKASNEDLAKRAKKLLRNWQKLIEPGPTGPASVPGSTNGSSHPCRTESSPADLSVSGKGVPEVKTRNDVHNTYSPKAEKSSSRKRRAEQRDSGVYLPEKISRMSSYDNSVSPPTNGIAGSPETLLDQEVVTSPDRSRIDNLENDKVNRIPINAVKPRPSSPGAAKPLSTSSLIKVAVMQQQARLDEGGGGGYQARSPRSVTSSPRSAKQDSVSKRSSAFAAKGTPIPSPSSRDSPLPFSHSVSSPGPMSYADKVTHSFHRSSVPPAASSDIPSHCPTQDFSAALESPSVSPSPLLPQLNSDPHRSTFEGTTAVSDDADGTAVQNSEHKRRKYRPRDFSVNLDGQKVEDSTKPVRLKERRITFDPVTGQIKPLVHKEPSQSEDVPTPDPAESRQRAQSVVPQSTATTSAPGPSPATGAGPNPFHQTNWKELSRNEIIQSYLNLQSNVLTSSGVQAPSAHFFMSEYLKREEQESKESRTSHVLQTDRLTGDLPGVSRDITEDDLDRIHKQNWPGVNGCYDTKGAWYDWTECISLDPHRDESKLNILPYVCLD
Length611
PositionUnknown
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.04
Grand average of hydropathy-0.795
Instability index71.18
Isoelectric point8.52
Molecular weight66673.30
Publications
PubMed=23542700

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22384
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     379.86|      68|      68|     204|     271|       1
---------------------------------------------------------------------------
   57-  108 (67.71/21.39)	...........INDVR....KKAS.....NEDLAK..RAKKLLR.....NWQKLIE..PGPTG..PASVP...............GSTNGS..SHPCRTE
  113-  200 (63.50/19.70)	DLSVSGKG...VPEVK....TRNDvhntySPKAEK..SSSRKRRAEQRDSGVYLPEkiSRMSSYdNSVSPptngiagspetlldqEVVTSP..DRS.RID
  204-  271 (109.84/38.31)	NDKVNRIP...INAVK....PRPS.....SPGAAKPLSTSSLIKVAVMQQQARLDE..GGGGGY.QARSP...............RSVTSS..PRSAKQD
  275-  329 (64.29/20.02)	K....RSS...AFAAKgtpiPSPS.....SRDS..PLPFSH...........SVSS..PGPMSY.ADKVT...............HSFHRSsvPPAA..S
  330-  396 (74.52/24.13)	SDIPSHCPtqdFSAAL....ESPS....vSPSPLLPQLNSDPHRSTFEGTTAVSDD..ADGTAV.QNSEH...............KRRKYR..PR.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.63|      48|      81|     441|     488|       2
---------------------------------------------------------------------------
  441-  488 (86.51/43.33)	SEDVPTPDPAESRQRAQSVVPQSTATTSAPGPS.PATGAGPNPFHQTNW
  523-  571 (77.11/37.88)	SEYLKREEQESKESRTSHVLQTDRLTGDLPGVSrDITEDDLDRIHKQNW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.00|      12|      18|     407|     418|       4
---------------------------------------------------------------------------
  407-  418 (20.00/12.98)	VEDSTKPVRLKE
  426-  437 (21.00/13.99)	VTGQIKPLVHKE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22384 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FFMSEYLKREEQESKESRTSHVLQTDRLTGDLPGVSRDITEDDLDR
2) LRNWQKLIEPGPTGPASVPGSTNGSSHPCRTESSPADLSVSGKGVPEVKTRNDVHNTYSPKAEKSSSRKRRAEQRDSGVYLPEKISRMSSYDNSVSPPTNGIAGSPETLLDQEVVTSPDRSRIDNLENDKVNRIPINAVKPRPSSPGAAKPLSTSSLIKVAVMQQQARLDEGGGGGYQARSPRSVTSSPRSAKQDSVSKRSSAFAAKGTPIPSPSSRDSPLPFSHSVSSPGPMSYADKVTHSFHRSSVPPAASSDIPSHCPTQDFSAALESPSVSPSPLLPQLNSDPHRSTFEGTTAVSDDADGTAVQNSEHKRRKYRPRDFSVNLDGQKVEDSTKPVRLKERRITFDPVTGQIKPLVHKEPSQSEDVPTPDPAESRQRAQSVVPQSTATTSAPGPSPATGAGPNPFHQTNWK
520
77
565
489










Molecular Recognition Features






MoRF SequenceStartStop




1) AKRAKKLLRNWQKLIE
2) LSTSSLIK
70
228
85
235