<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22350

Description Mediator complex subunit 23
SequenceMALSMEAQLQSIFEDVVKTVMIEEAFAGMFMDTPEDERTKLISCLGAFRQYWGTLPLESHEQCVQWIVRFIHSQHSPKRISFLYECLAMAVETSLLPPRMVCAALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKALLDKIQTIPTTVSSSIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPSTLHFPLKGMLPFDKVTFFDFKLIKDTCMGKHSDEFISLSHQELFEPQTGLLRYVLEQPYSREMVCNMLGLNKQQKQRCPVLEEQLVDLVVYAMERSESEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLNKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLGMSDYKIALLCNAYSTNSECFPLPMGALVETIYGNGTMRINLPGTNCMASAAVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKCHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFSRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHENNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGSLYKFHDRPVTYLYNTLHYYERQLRDRTNLKRKLVHAIMSSLKDNRSPGWCLSETYLKFGINPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSFMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSIVETSSSAAAATSSSSATSSTPQPPSSSLSTSAAASPSSSQHAHTAM
Length1410
PositionTail
OrganismTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
KingdomMetazoa
Lineage
Aromaticity0.10
Grand average of hydropathy-0.019
Instability index44.94
Isoelectric point6.89
Molecular weight160707.46
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22350
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.47|      42|     877|      40|      98|       1
---------------------------------------------------------------------------
   42-   93 (68.96/68.11)	ISCLGA.....FRQ....................YWGTLPLESHeqcvqwIVRFIHSQHSPKrisfLYECL..AMAVET
  765-  833 (58.51/31.40)	LSCFPAplqafFKQnnvpqesrfnlkknveeeyrKWKSMANEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.55|      20|      36|     293|     312|       2
---------------------------------------------------------------------------
  293-  312 (35.36/29.31)	LFEPQTGLLRYVLEQPYSRE
  331-  350 (32.19/25.85)	LEEQLVDLVVYAMERSESEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.15|      11|     295|     617|     627|       4
---------------------------------------------------------------------------
  617-  627 (21.86/12.49)	FISQLL...PNVFK
  917-  930 (17.29/ 8.30)	FIIQLLllkPNDFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.77|      40|     366|     949|    1003|       6
---------------------------------------------------------------------------
  949- 1003 (65.97/70.68)	DWHNKHMN.........YHKKYpekLYF.EGLAEQVN.......PPMQLQpqylpiyfgnvcLRFLPVFDIV
 1309- 1365 (57.80/32.70)	DQHCQHLSfmdpicdflYHIKY...MYTgDSVKEQVEkiimtlrPAMKLR............LRFITHSSIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     372|     381|      10
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  372-  381 (18.69/11.32)	IFFVLFQFAS
  405-  414 (19.45/12.12)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.54|      17|     463|     667|     683|      11
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  667-  683 (31.77/20.50)	PQTNQNQLHL.CVESTAL
 1131- 1148 (27.77/16.93)	PNPAAHALHVtCVELMAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.77|      18|     580|     526|     547|      13
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  526-  547 (29.98/29.15)	GALVETIYGNGTMrinlPGTNC
 1106- 1123 (36.78/24.15)	GRLVDTMAGKSPG....PFPNC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22350 with Med23 domain of Kingdom Metazoa
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