<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22296

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKRNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYAISSQVNAFTEPCYFDDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGITVWLLQGCAFYCEKLRELGPLASTEASLAACQERLHGLLNSTKNRALIHIARLEEQSFWSNVDQAMLKVSEVLSSVSNQALKTKIEESLALVKSVPQMLSMQSDPPVNVSFPSVHAFIMLEGTMNLTGELQPLVEQLMMIKRMQQIPTPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPMGDRGQDFMDDVNIAFEYLLKLTPLLDKADQRSECHKLVLLSEKNTTNLTAKRTEDREYAPKLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHITGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSEPSPSGETPFFETWLQTCMPEEGKILNPDHPCFKPEPGKVENLVTLLNNSSEMKLVQVKWHEICLNTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGRDEREKPQTMIRHLVTPLYGENTLQFYNERVIIMSSIMEHMCADIFQQTGATVRPPMEGHEPIPYRNLLPTKEPIHAALSQQFQAVLRKGWVDSRALHLFESLLNMGGVFWFTNNLVKELLKETRQEWANRVVELLYSIFCLDTQQITLTLLGTILPNLLTDSAHWHSLTDPPGKALAKLAVWCALSSYSSHHKGPLSARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPVALSSPDLTYMFSSANLFFLISSILGSKMAGPHTQFVQSFIEECVECLEQGSRGSILQFMPFTMVSELVKLPALAKPKVVLAITDLSLPLGRRVAAKAISAL
Length956
PositionTail
OrganismPeriophthalmus magnuspinnatus
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Gobiaria> Gobiiformes> Gobioidei> Gobiidae> Oxudercinae> Periophthalmus.
Aromaticity0.08
Grand average of hydropathy-0.034
Instability index46.76
Isoelectric point6.40
Molecular weight107256.65
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22296
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.74|      14|      15|     720|     734|       1
---------------------------------------------------------------------------
  720-  734 (21.54/21.84)	LLNMGGVFWfTNNLV
  737-  750 (24.21/17.48)	LLKETRQEW.ANRVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.50|      22|      31|     164|     194|       3
---------------------------------------------------------------------------
  164-  187 (33.05/37.86)	STKNRALihIARLEEQ.SFWSNVDQ
  198-  220 (30.45/12.73)	SVSNQAL..KTKIEESlALVKSVPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     202.38|      65|     194|     563|     628|       4
---------------------------------------------------------------------------
  563-  628 (108.11/84.53)	CLNTPAAILEVLNAWENGVLSVEA.VQKITDNiKGK.VCSMAI.CAVAWLVAHVR.MLGRDEREKPQTMI
  758-  826 (94.28/68.39)	CLDTQQITLTLLGTILPNLLTDSAhWHSLTDP.PGKaLAKLAVwCALSSYSSHHKgPLSARQRKRQREDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.23|      10|      17|     113|     122|       5
---------------------------------------------------------------------------
  113-  122 (20.06/12.23)	CIGLCRAL..LG
  131-  142 (16.17/ 8.42)	CAFYCEKLreLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.39|      24|     382|      85|     108|       6
---------------------------------------------------------------------------
   85-  108 (45.61/30.87)	SRELCVKSLLEIMD..MFCHRLSCHG
  468-  493 (36.78/23.52)	SKSASVRALLFDISflMLCHVVQTYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.71|      15|     623|     221|     235|       9
---------------------------------------------------------------------------
  221-  235 (29.53/17.89)	MLSMQSDPPVNVSFP
  846-  860 (26.19/15.06)	LLSSNEDEPVALSSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.75|      19|     623|     294|     321|      13
---------------------------------------------------------------------------
  294-  321 (22.37/40.24)	EELKwTAFTFLkipqvllrLKKYPMGDR
  327-  345 (32.38/21.89)	DDVN.IAFEYL........LKLTPLLDK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22296 with Med24 domain of Kingdom Metazoa
Unable to open file!