<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22256

Description Uncharacterized protein
SequenceMTTVSTTPQQIRDRLLQAIDSQSNICNMVIVLEVINCLEKYPITKEALEETRLGKLINDIRKKTKDEDLAKRAKKLLKNWQKLIEPGPVVAPSVTGSTNGSSHLCRTDPSPPEISVLGKGFADVRMRNYVQNTYSPKAEKSSKRKVEHSRLHLTENLSKTSTYDNSVSPLPTNGIAGSPRTQFEQDVTVSPGKCRVDHLDDDRVNRTSVNSVRPCPNSPGVEKLPSTSSLVKVAVIQQHARLEEEGGSYNQGKSPRSVTSSPRSQKHDSLPKRSVPYGLKGTPIPSPSSRDSPLSFSQALASPGQPSFAEKLPHLSHKPLSHTTSLYEPQDVSGTLDSPSASPLLCQQNTESQRSRLEAGFVVSDDTDRMTAANSEHKRRKYKSRDFSINLDGQKVEDTTKRVRLKERRLTFDPVTGQIKPLVHKDPSPVEVSSTPDPAEFRQRTESSVQQSAATTTSPCPNPFLQTNWKELSRNEIIQSYLNLQSNLLTSSGVQTPSAHFFMSEYLKREEQETKESKKMHVLQTDSSKGDLPGMSRQLTDKDLERIHTQQWPGVNGCYDTNGTWYAWTECISLDPHGDENKLNILPYVCLD
Length592
PositionUnknown
OrganismOryzias latipes (Japanese rice fish) (Japanese killifish)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Beloniformes> Adrianichthyidae> Oryziinae> Oryzias.
Aromaticity0.05
Grand average of hydropathy-0.787
Instability index61.30
Isoelectric point8.79
Molecular weight65937.17
Publications
PubMed=17554307

Function

Annotated function
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP22256
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     254.95|      44|      44|     152|     195|       1
---------------------------------------------------------------------------
  104-  145 (39.82/17.87)	......LCR.TDPS.........PP.EISVL.GK.GFADVRMRNYVQN....TYSPkaeksS.KRK
  152-  195 (77.15/41.31)	HLTEN.LSK.TSTY.........DN.SVSPLPTN.GIAGSPRTQFEQDV...TVSP.....G.KCR
  198-  241 (50.16/24.36)	HLDDDrVNR.TSV...........N.SVRPCPNSpGVEKLPSTSSLVKV...AVIQ.....Q.HAR
  243-  282 (41.78/19.10)	E..EE.....GGSY.........NQ.GKSP...R.SVTSSPRSQKHDSLpkrSVPY.....GlKGT
  317-  369 (46.05/21.78)	H..KP.LSHtTSLYepqdvsgtlDSpSASPLLCQ.QNTESQRSRLEAGF...VVSD.....D.TDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.12|      27|     460|      45|     100|       2
---------------------------------------------------------------------------
   61-   96 (37.08/70.22)	RK.KTKD..........EDLAKRAKklLKNWQKLIEPgpvvapsVTG
  380-  417 (36.04/ 8.14)	RKyKSRDfsinldgqkvEDTTKRVR..LKERRLTFDP.......VTG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP22256 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ETKESKKMHVLQTDSSKGDLPGMSRQLTDKDLER
2) NYVQNTYSPKAEKSSKRKVEHSRLHLTENLSKTSTYDNSVSPLPTNGIAGSPRTQFEQDVTVSPGKCRVDHLDDDRVNRTSVNSVRPCPNSPGVEKLPSTSSLVKVAVIQQHARLEEEGGSYNQGKSPRSVTSSPRSQKHDSLPKRSVPYGLKGTPIPSPSSRDSPLSFSQALASPGQPSFAEKLPHLSHKPLSHTTSLYEPQDVSGTLDSPSASPLLCQQNTESQRSRLEAGFVVSDDTDRMTAANSEHKRRKYKSRDFSINLDGQKVEDTTKRVRLKERRLT
3) PVTGQIKPLVHKDPSPVEVSSTPDPAEFRQRTESSVQQSAATTTSPCPNPFLQ
513
128
414
546
411
466

Molecular Recognition Features

MoRF SequenceStartStop
NANANA