<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22225

Description Uncharacterized protein
SequenceMDPAPKIGANQVSDVVFVIEGTANLGPYFESLRKNYILPAIYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAYEFVSWIDKIFMGGGAESCSLIAEGLSVALQLFDDFKKMREQGQTHKVCVLLCNSPPYLLPAVESVSYTGCTTDNLVQIIRDKGIHFSVVAPRKLPALRALFERASPVGAPSESSHPDYSQDPFHMVLIRGIALPAPGGGSGPVPLKPVLPPQPMNVSQPPPIGAASQVPPISANHPYQPGMVNAGPPFSTQPVKLTSVSQPSLSTVTTVSTPMLQQQQAPPQQQPQPSQVPPPGQPTPNQQAPQPPQQQQAPNQQPPPSSQPGMSASPANSIGGQQGVPNKVVAWSGVLEWQEKPKASSMDSNTKLTRSLPCQVQVNQGENNAEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDVESLKGLYRIMANGFAGCVHFPHSAPCEVRVLMLLYSSKKRIFMGLIPNDQSGFVNGIRQVITNHKQVQQHRTMQTGQVPPNQNFLNRPPGPIPVTHGNVQQQRAAATANQQPPVSGAPPNQVAQGQPQAPGNMLRLPNPGANPQLRSLLLSQQQPQSGVSHMQGMLPLQGLNQQMVHPAGGAQIQPQWRQPGQMLMAGGPRGSVAQNPGMPQVSSVMEDEILMDLI
Length676
PositionUnknown
OrganismAstyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Characiformes> Characoidei> Characidae> Astyanax.
Aromaticity0.06
Grand average of hydropathy-0.349
Instability index54.01
Isoelectric point8.63
Molecular weight72684.13
Publications
PubMed=25329095

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22225
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.95|      22|      23|     303|     324|       1
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  309-  333 (41.50/11.88)	PQQQPQPSQVPPPG.QP........tpnQQAPQP
  334-  367 (30.45/ 6.54)	PQQQQAPNQQPPPSsQPgmsaspansigGQQGVP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     197.06|      36|      38|     173|     210|       2
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  144-  171 (33.00/11.55)	......PYLLPAV....ESVSYTGCTTD.....N.....LVQIIRDKG
  173-  210 (58.46/31.50)	HFSVVAPRKLPALRAlfERASPVGAPSE.....S.....SHPDYSQDP
  212-  241 (49.63/21.27)	HMVLIRGIALPAPGG...GSGPV..........P.....LKPVLPPQP
  243-  268 (24.95/ 6.84)	NVS...............QPPPIGAASQvppisA.....NHP.YQPG.
  275-  305 (31.03/10.39)	PFS.TQPVKL..........TSVSQPSL.....StvttvSTPMLQQQ.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.96|      29|      29|     493|     521|       3
---------------------------------------------------------------------------
  493-  521 (52.77/23.20)	M..GLIPNDQSGFVN.GI..RQVITNHKQVQQHR
  523-  553 (42.25/17.01)	MqtGQVPPNQN.FLNrPP..GPIPVTHGNVQQQR
  554-  578 (24.94/ 6.82)	A..AATANQQPP.VS.GAppNQVAQGQPQ.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.99|      21|      21|     620|     640|       4
---------------------------------------------------------------------------
  398-  416 (29.44/ 9.13)	.LPCQ.V...QVNQGENNAEQWPQ
  620-  640 (41.35/15.73)	GLNQQMV...HPAGGAQIQPQWRQ
  642-  662 (27.19/ 7.88)	G...QMLmagGPRGSVAQNPGMPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.28|      25|      27|     431|     457|       5
---------------------------------------------------------------------------
  431-  457 (38.40/30.84)	LGPLFrnSRMVQFLFTNK.DVESLKGLY
  460-  485 (41.88/26.68)	MANGF..AGCVHFPHSAPcEVRVLMLLY
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22225 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSGPVPLKPVLPPQPMNVSQPPPIGAASQVPPISANHPYQPGMVNAGPPFSTQPVKLTSVSQPSLSTVTTVSTPMLQQQQAPPQQQPQPSQVPPPGQPTPNQQAPQPPQQQQAPNQQPPPSSQPGMSASPANSIGGQQGVP
2) HKQVQQHRTMQTGQVPPNQNFLNRPPGPIPVTHGNVQQQRAAATANQQPPVSGAPPNQVAQGQPQAPGNMLRLPNPGANPQLRSLLLSQQQPQSGVSHMQGMLPLQGLNQQMVHPAGGAQIQPQWRQPGQMLMAGGPRGSVAQNPGMPQVSSVME
227
514
367
668










Molecular Recognition Features






MoRF SequenceStartStop




NANANA