<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22204

Description Uncharacterized protein
SequenceMDPAPKIGANQVSDVVFVIEGTANLGPYFESLRKNYILPAIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAYEFVSWIDKIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTTDNLVQIIRDKGIHFSVVAPRKLPALRALFERASPVGAPSESSHPDYSQDPFHMVLIRGIALPVPGMVNAGPPFSTQPVKLTSVSQPSLSTVTTVSTPMLQQQQAPPQQQPQPSQVPPPGQPTPNQQAPQPPQQQQAPNQQPPPSSQPGMPGVSASPANSIGGQQGVPNKVVAWSGVLEWQEKPKASSMDSNTKLTRSLPCQVQVNQGENLNAEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDVESLKGLYRIMANGFAGCVHFPHSAPCEVRVLMLLYSSKKRIFMGLIPNDQSGFVNGIRQVITNHKQVQQHRTMQTGQVPPNQNFLNRPPGPIPVTHGNVQQQSVVVGMAPVSQVTMMEDQQRQNTMLTMRAAATANQQPPVSGAPPNQVAQGQPQAPGNMLRLPNPGANPQLRSLLLSQQQPQSGVSHMQGMLPLQGLNQQMVHPAGGAQIQPQWRQPIAGPGQMLMAGGPRGSVAQNPGMPQVSSVMEDEILMDLI
Length671
PositionUnknown
OrganismAstyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Characiformes> Characoidei> Characidae> Astyanax.
Aromaticity0.06
Grand average of hydropathy-0.313
Instability index52.76
Isoelectric point8.03
Molecular weight72523.09
Publications
PubMed=25329095

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22204
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     151.54|      21|      32|     523|     543|       1
---------------------------------------------------------------------------
  259-  278 (26.63/ 6.42)	TPMLQQQ..QAPPQQqPQP..SQV
  279-  298 (27.93/ 7.11)	PPPGQPTpnQQAPQP.PQQQ...Q
  523-  543 (31.89/ 9.25)	APVSQVT..MMEDQQ.RQNTMLTM
  558-  577 (33.47/10.10)	APPNQVA..QGQPQA.PGN.MLRL
  583-  603 (31.62/ 9.10)	NPQLRSL..LLSQQQ.PQSGVSHM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.71|      18|      25|     195|     216|       2
---------------------------------------------------------------------------
  204-  229 (30.57/14.44)	SSHPDYSQDPFHMvlirgialPV..PGM
  231-  251 (23.15/12.38)	NAGPPFSTQPVKL.......tSVsqPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.62|      26|      30|     458|     484|       3
---------------------------------------------------------------------------
  458-  484 (43.24/26.32)	GLIPNDQSgFVNGIRQVIT.NHKQVQQH
  490-  516 (47.39/24.64)	GQVPPNQN.FLNRPPGPIPvTHGNVQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.50|      13|      23|     608|     622|       4
---------------------------------------------------------------------------
  608-  622 (20.30/12.34)	PLQGLNQQMVhpAGG
  632-  644 (26.20/ 9.86)	PIAGPGQMLM..AGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.52|      14|      23|     302|     315|       5
---------------------------------------------------------------------------
  302-  315 (29.13/16.31)	QQPPPSSQPGMPGV
  326-  339 (24.38/12.14)	QQGVPNKVVAWSGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.09|      22|      23|     356|     377|       6
---------------------------------------------------------------------------
  356-  377 (37.56/19.57)	KLTRSL.PCQVQVNQGENLNAEQ
  381-  403 (30.53/14.58)	KLIMQLiPQQLLTTLGPLFRNSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.76|      17|      25|     405|     421|       8
---------------------------------------------------------------------------
  405-  421 (29.06/17.49)	VQFLFTNK.DVESLKGLY
  432-  449 (26.70/15.54)	VHFPHSAPcEVRVLMLLY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22204 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMVNAGPPFSTQPVKLTSVSQPSLSTVTTVSTPMLQQQQAPPQQQPQPSQVPPPGQPTPNQQAPQPPQQQQAPNQQPPPSSQPGMPGVSASPANSIGGQQGV
2) HKQVQQHRTMQTGQVPPNQNFLNRPPGPIPVTHGNV
3) PVSQVTMMEDQQRQNTMLTMRAAATANQQPPVSGAPPNQVAQGQPQAPGNMLRLPNPGANPQLRSLLLSQQQPQSGVSHMQGMLPLQGLNQQMVHPAGGAQIQPQWRQPIAGPGQMLMAGGPRGSVAQNPGMPQVSSVM
228
478
524
329
513
662










Molecular Recognition Features






MoRF SequenceStartStop




NANANA