<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22181

Description Blast:Mediator of RNA polymerase II transcription subunit 24
SequenceMFVYPFQLVLNYLKHSLCAHLVSHGAVLRCIAKYDKLERVYCITSLLEFLVGIVDGVTCRIKSEEAVLPGAVVQLVYWLLQIFARTVLHYELYGEISAEQSYMLDQTCAVIDRISQHQFMLSMLYVGCHEEFECHGKIRDKYATIKGSLTNSNFTLSSPGVEQQLQQFAYIDVSHLDLQQLNVLPAEKISYCVQPLLAVEVLLIPCKETSYYVAELQMLQRLKRYTNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMFFKMPHIIKQLHALQRVPGEQPPPADYIPELVEALELLIQDNLLLDYMDTKCSCNMIEFLLNDWTKQQLVNDVHVKKFASQREASSLLLKKCDNGQQTPSNIIFIKRAEVPLSGVLKTLCTNKVQDMVNVLCQVPVGNSFELILSVATVDGRLKTFVSRLIQCNENSKPVPAELGKLNVTRSTLFDVSFLMLTSIVQTYGSDVVLSDRGDSFFEKWVRECMVERNKLKNPRQILALCDDSMVDELLLSLSKPEAAQLKPCTLSWQETCLNLPGVLHHVLIAWEQETLSSADVKSILDNIKRRLFSFSVCATSFLCAYMYSVRETELLKPLNMIQQFLAPLTSEELSSQEYAKERLALSYPIIRKMQHDVHPAPSTKSRLISHSPLIEQFREVWKTVAEAGHLPVRAAQTLESLLLAGGAAWLATQLVEQLLTCKYIRDMSKAMDIVFAVMHLDIEKSTEALLQYVVPPLMLRRQGEDINEPQSLVLARLCVYCVISCLETRSAAASSSLKKRSRSHDEEEQASNVAKLRKVIGDGSENSNDFTDNAAAGLAGGPRLASPSSTEVRATPLSLREPLQSSIQHIFGVFVQFVSGDELSPKAVFVYQFISLLVECGGERVAPVLRLLPANLVQQLLKVLPTEDIRVGLISRLYDLRVPGGRQAAVSDLCLWRNMQMARHSIHL
Length938
PositionTail
OrganismDrosophila guanche (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.08
Grand average of hydropathy0.065
Instability index49.32
Isoelectric point6.30
Molecular weight105579.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22181
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.34|      15|      15|     658|     672|       1
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  658-  672 (25.42/16.95)	GHLPVRAAQTLESLL
  675-  689 (25.92/17.43)	GGAAWLATQLVEQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.95|      12|      15|     836|     849|       2
---------------------------------------------------------------------------
  836-  849 (14.20/19.19)	SIQHIFgVFvQFVS
  854-  865 (22.75/15.25)	SPKAVF.VY.QFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.72|      13|      15|     515|     527|       3
---------------------------------------------------------------------------
  515-  527 (25.02/15.81)	LKPCTLSWQETCL
  533-  545 (22.70/13.66)	LHHVLIAWEQETL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.08|      44|      87|     142|     188|       7
---------------------------------------------------------------------------
  142-  188 (67.14/61.99)	YATIK.GSLTNSNFTLSSPgvEQQLQQFAYIDVSHLdLQQLNVL...PAEK
  232-  279 (72.94/54.19)	YEIIRaGFLTLSNVADTSP..DTMWGAFMFFKMPHI.IKQLHALqrvPGEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.97|      16|      16|     801|     816|       8
---------------------------------------------------------------------------
  801-  816 (26.42/17.52)	TDNAAAGLAGGPRLAS
  820-  835 (26.55/17.65)	TEVRATPLSLREPLQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.17|      21|     813|      69|      89|       9
---------------------------------------------------------------------------
   69-   89 (38.63/30.06)	PG....AVVQLVYWLLQIFARTVLH
  913-  937 (36.54/27.97)	PGgrqaAVSDLCLWRNMQMARHSIH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22181 with Med24 domain of Kingdom Metazoa
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