<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22179

Description Blast:Mediator of RNA polymerase II transcription subunit 24
SequenceMKENNKILQLIYVAWRERWSDSQWGINIKKVLPRGVSGDVYNLADCLMQQALIGSTANPLVLNYLKHSLCAHLVSHGAVLRCIAKYDKLERVYCITSLLEFLVGIVDGVTCRIKSEEAVLPGAVVQLVYWLLQIFARTVLHYELYGEISAEQSYMLDQTCAVIDRISQHQFMLSMLYVGCHEEFECHGKIRDKYATIKGSLTNSNFTLSSPGVEQQLQQFAYIDVSHLDLQQLNVLPAEKISYCVQPLLAVEVLLIPCKETSYYVAELQMLQRLKRYTNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMFFKMPHIIKQLHALQRVPGEQPPPADYIPELVEALELLIQDNLLLDYMDTKCSCNMIEFLLNDWTKQQLVNDVHVKKFASQREASSLLLKKCDNGQQTPSNIIFIKRAEVPLSGVLKTLCTNKVQDMVNVLCQVPVGNSFELILSVATVDGRLKTFVSRLIQCNENSKPVPAELGKLNVTRSTLFDVSFLMLTSIVQTYGSDVVLSDRGDSFFEKWVRECMVERNKLKNPRQILALCDDSMVDELLLSLSKPEAAQLKPCTLSWQETCLNLPGVLHHVLIAWEQETLSSADVKSILDNIKRRLFSFSVCATSFLCAYMYSVRETELLKPLNMIQQFLAPLTSEELSSQEYAKERLALSYPIIRKMQHDVHPAPSTKSRLISHSPLIEQFREVWKTVAEAGHLPVRAAQTLESLLLAGGAAWLATQLVEQLLTCKYIRDMSKAMDIVFAVMHLDIEKSTEALLQYVVPPLMLRRQGEDINEPQSLVLARLCVYCVISCLETRSAAASSSLKKRSRSHDEEEQASNVAKLRKVIGDGSENSNDFTDNAAAGLAGGPRLASPSSTEVRATPLSLREPLQSSIQHIFGVFVQFVSGDELSPKAVFVYQFISLLVECGGERVAPVLRLLPANLVQQLLKVLPTEDIRVGLISRLYDLRVPGGRQAAVSDLCLWRNMQMARHSIHL
Length990
PositionTail
OrganismDrosophila guanche (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.07
Grand average of hydropathy0.040
Instability index48.89
Isoelectric point6.45
Molecular weight111382.13
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22179
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.20|      37|      87|     121|     205|       1
---------------------------------------------------------------------------
  121-  162 (56.88/94.14)	PGavVQLVywlLQIFAR.TVLHYEL..YGEISAEQ.SYMLDQTCAV
  211-  251 (53.33/13.46)	PG..VEQQ...LQQFAYiDVSHLDLqqLNVLPAEKiSYCVQPLLAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.34|      15|      15|     710|     724|       2
---------------------------------------------------------------------------
  710-  724 (25.42/15.60)	GHLPVRAAQTLESLL
  727-  741 (25.92/16.04)	GGAAWLATQLVEQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.95|      12|      15|     888|     901|       3
---------------------------------------------------------------------------
  888-  901 (14.20/17.89)	SIQHIFgVFvQFVS
  906-  917 (22.75/14.21)	SPKAVF.VY.QFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.72|      13|      16|     567|     579|       4
---------------------------------------------------------------------------
  567-  579 (25.02/13.28)	LKPCTLSWQETCL
  585-  597 (22.70/11.43)	LHHVLIAWEQETL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.97|      16|      16|     853|     868|       5
---------------------------------------------------------------------------
  853-  868 (26.42/19.55)	TDNAAAGLAGGPRLAS
  872-  887 (26.55/19.70)	TEVRATPLSLREPLQS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22179 with Med24 domain of Kingdom Metazoa
Unable to open file!