Description | Uncharacterized protein |
Sequence | MAANYWVSTQRRYWLFSREKLAEAREKLKERDNVAYSQLPLPDQRLLNIYFSQQLSKLGKRMSTRQQALATAQIYVKRFYTKKELRHTNPYLILTTAFYLACKMEECPHHIRFVVGEARSLWPDFITPDISKLGECEFALIAEMNSQLIVHHPYRTLSELQSDLSLTSDEVALAWSVINDHYLTDLPLLYAPHVIAVMAIIIAVVFKPSQTSFHGSAAPSLTAAMRDGSTNIFAALGDKGGNAPRIQKLVSWLAESDVDIRAVVECTQELVSLYEIWEQYNEKHCKELLMRMVKNKNLYK |
Length | 300 |
Position | Kinase |
Organism | Aspergillus sclerotialis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus> Aspergillus subgen. Polypaecilum. |
Aromaticity | 0.10 |
Grand average of hydropathy | -0.180 |
Instability index | 45.18 |
Isoelectric point | 8.47 |
Molecular weight | 34491.44 |
Publications |
Annotated function |
Component of the SRB8-11 complex. The SRB8-11 complex is a
regulatory module of the Mediator complex which is itself involved in
regulation of basal and activated RNA polymerase II-dependent
transcription. The SRB8-11 complex may be involved in the
transcriptional repression of a subset of genes regulated by Mediator.
It may inhibit the association of the Mediator complex with RNA
polymerase II to form the holoenzyme complex. The SRB8-11 complex
phosphorylates the C-terminal domain (CTD) of the largest subunit of
RNA polymerase II.
Component of the srb8-11 complex. The srb8-11 complex is a
regulatory module of the Mediator complex which is itself involved in
regulation of basal and activated RNA polymerase II-dependent
transcription. The srb8-11 complex may be involved in the
transcriptional repression of a subset of genes regulated by Mediator.
It may inhibit the association of the Mediator complex with RNA
polymerase II to form the holoenzyme complex. The srb8-11 complex
phosphorylates the C-terminal domain (CTD) of the largest subunit of
RNA polymerase II.
ECO:0000256 ARBA:ARBA00002306 ECO:0000256 ARBA:ARBA00003882 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP22175 No repeats found |
MoRF Sequence | Start | Stop |
1) RLLNIYFS 2) RRYWLF | 45 11 | 52 16 |
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