<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22157

Description Uncharacterized protein
SequenceMSTVLFRQYYSAGARIIDCYPLCDSDSLLHVRDNSRAICPRKNHGYTLESAGITSTIYKSVEEAIHQIITAGRRSSRRADCAYTDSVYQVPTVAKRKSRCDPGIPRCSPCERSNAKCVYYDSARKCTIPRTYIVSLREKARMLEKELADLEKDIQHAADAELMVRGAGRIRFKENDESRYLGPSSGIAITRLVMEMAKQNTDSKSIKDVVPEFTAQEIKAAFAQESSKPTSKVYPMISSIPQPNLPPRNLTYRLIDVFVVKAQAMLPTLHEPSFRQEVEQVFNGSDDPCLNFQLRMVIAISMQKMSTEYAGLADSYYLAALPYLEASLRRMDLRALQCLVLIAQYSLLTPTRTAAYWVVGMAVKLCQDLGLTEEATVTKSPDGRPLNPLEVDMRRRLFWIVTSMELGLSHSLGRPSCYSIPHDYINVKFFELVDDRYITADGILPGEIRRTLYLNKRDTPANDQDPWFSQMLAKLDHWVASCPKNDGGSGLSEKWFHGRRNTMIVFMFRPSPQVPEPSVDAARKCYEASVFNVAMQREQIATGSVDLTWIFTQSLFMALNTILWSLSYPDIRREHPIEEVRAHLDVALEAMMLAAERWPGVESALLLYKSLVTACLKAYNTDESFVVQSPSNHATPSSTQDVTTPPSISSPSSTTTSFRAGNHSIHDTVSVGTVSRGQSADPTFPYSQASPAAAVRAEPQKPPSYSHWETEFPSLQPSVSNSARTSYTPQGYTESSTVFSDATFNPTTPFNSFPSVVPGLPGWDPNFTVASTTASHLAYVDAVIDPMRWMDTIDDQYSQYFNGAFPIPPWRGRTLSQQEQIELMASLEENIPDVSAQLTPTSPPLMSVSAQNYATNIASSQPPGQATSQPANLSSPPSSAPMSTQTSQQPTLGTTNSFPTPASSVSGHFTGPTLVDDSEHPGTSFEHVQADSVATTATGLHSASTQQSQHRRTDHDRDLGGPTPGIDVRDFASMGGQHARIDADAMDIDKGVIASAKSDGLSLESLQQDFSSAFHLCKSSHIATGPDPALDLISLYGLGPVAKSVARMDPVTGEKINRLRKSYEGKLKGLGLAGRNKPVKHEPSAPGGLRHLTIWPEEEWQNQKVHGKEIKVADMDSALHNLQMKAMHMEPGTVPNNEYWEDVLGHEKPSKHAGHGDGKKAAALPSNARSPSQVNDTPLSTEPERARPSRGRKRHYDDNSFVGYGEGYADDDDDAAFYSNSEGIGKKKRKKDHVSKVSTPLPDRGGSYGVGMFGIGAR
Length1258
PositionHead
OrganismAspergillus thermomutatus
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.08
Grand average of hydropathy-0.459
Instability index47.22
Isoelectric point6.27
Molecular weight138420.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22157
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     302.12|      58|      60|     844|     901|       1
---------------------------------------------------------------------------
  630-  668 (32.81/12.75)	.................................PS..N......HATpSSTQDVTTPPSiSSPSSTTTSF......RA..GNH...SIHDT.
  706-  756 (60.44/30.56)	...................S.HWET..EFPSLQP...........SV.SNSARTSYTPQ.GYTESSTVFS......DATFNPTtpfNSFPSV
  776-  844 (56.21/27.83)	HLAYVDAvidpmrwmdtidD.QYSQyfNGAFPIPPwrG......RTL.SQQEQIELMAS.LEENIPDVSA......Q....LT...PTSP.P
  845-  900 (90.59/49.99)	.LMSVSA............Q.NYAT..NIASSQPP..G......QAT.SQPANLSSPPS.SAPMSTQTSQ......QPTLGTT...NSFPT.
  901-  964 (62.06/31.60)	PASSVSG............HfTGPT..LVDDSEHP..GtsfehvQAD.S.VATTATGLH.SA..STQQSQhrrtdhDRDLGG.......PTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.43|      19|     101|     240|     261|       2
---------------------------------------------------------------------------
  240-  258 (33.83/24.45)	IPQPNLPPRNLTYRLIDVF
  264-  282 (32.60/15.17)	AMLPTLHEPSFRQEVEQVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.87|      15|      23|      63|      77|       3
---------------------------------------------------------------------------
   63-   77 (25.35/17.75)	EAIHQIITAGRRSSR
   85-   99 (25.52/17.93)	DSVYQVPTVAKRKSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.34|      18|      23|     513|     531|       4
---------------------------------------------------------------------------
  513-  531 (28.30/23.65)	QVPEPSVDAARkCYEASVF
  539-  556 (32.04/21.58)	QIATGSVDLTW.IFTQSLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.92|      13|      25|     456|     468|       5
---------------------------------------------------------------------------
  456-  468 (26.34/13.18)	KRDTPANDQDPWF
  484-  496 (24.58/11.86)	KNDGGSGLSEKWF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.52|      14|      26|     993|    1006|      10
---------------------------------------------------------------------------
  993- 1006 (22.21/13.69)	IASAKSDGLSLESL
 1022- 1035 (24.31/15.81)	IATGPDPALDLISL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.57|      15|      62|     307|     325|      13
---------------------------------------------------------------------------
  308-  322 (27.38/21.54)	EYAGLADSYYLAALP
 1151- 1165 (28.18/ 8.09)	KHAGHGDGKKAAALP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22157 with Med19 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DDDAAFYSNSEGIGKKKRKKDHVSKVSTPLPDRGGSYGVGM
2) QKVHGKEIKVADMDSALHNLQMKAMHMEPGTVPNNEYWEDVLGHEKPSKHAGHGDGKKAAALPSNARSPSQVNDTPLSTEPERARPSRGRKRHYDDNSFVGYG
3) RGRTLSQQEQIELMASLEENIPDVSAQLTPTSPPLMSVSAQNYATNIASSQPPGQATSQPANLSSPPSSAPMSTQTSQQPTLGTTNSFPTPASSVSGHFTGPTLVDDSEHPGTSFEHVQADSVATTATGLHSASTQQSQHRRTDHDRDLGGPTPGIDVRDFASMGGQHARIDADAMDI
4) VQSPSNHATPSSTQDVTTPPSISSPSSTTTSFRAGNHSIHDTVSVGTVSRGQSADPTFPYSQASPAAAVRAEPQKPPSYSHWETEFPSLQPSVSNSARTSYTPQGY
1212
1103
811
627
1252
1205
988
732










Molecular Recognition Features






MoRF SequenceStartStop




1) MFGIGAR
1252
1258