<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22132

Description Rna polymerase ii holoenzyme cyclin subunit
SequenceMGENLVIYYNDSIDSDNLAAAMALWKATYQRPNTRLIWIIEPRQVCFGLSMTAEQVSRCKDLIQEHFSLLGNPFKVLLGGLIKQADLDNIKDLTEADRHLLQMAVKSKYGSKDDAVLHGRLTAWDFASCLAEWSNNAANEVFVDFESLSEIENPVNLNFHHHEELVNRSAEELKAYDDILKESFPQRTQSLRNWYEKCARRIEKEECNSNTFVKPLNLNAVYDAIETAASARFFGGSSLRILRQFLDKGVAGKIKCHLQVGSCDMSANLFANQFNIALNREAAKTVLSRSTEFSKFTVVPSHTAQSIKYSALGLKNAGGHCLEKRILGFNCREDPFKIVTNNVSLDGQYSDKAYAMPDLTAFLCVLVPKYMQDKGSKLGFIQVDEKGCNGALLFRPSDEGIQILQQPQAVVNVLSFNCPGIGLRLIIIYSGVMSASYWQSTQCRFWTFTKEQLATMRQKLEEDNAELVRMFPLPQQRHLNIYFNQQLIRLAKRLTIRQQSMATAQVYMKRFYSKVEIRRTNPYLVIATAIYLACKIEESPQHIRLIVTEARQMWGDLVAIDTSKLGECEFFMISEMQSQLIIFQPYRTITALRSELGLQEDEVQLARSVINDHFMTDLPLLYPPHVVAMVAMLLALVLRPNNSGPGQNASGAAAAAGLAAAQQALMRAQGQQTPGAATDAVNPEPKERQQQARVSRVQKFAKWLVDSNVDIASMVDATQEIISFYECYEHYNDKLTREQINRFVKARGLDK
Length751
PositionKinase
OrganismFusarium longipes
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium.
Aromaticity0.09
Grand average of hydropathy-0.219
Instability index48.38
Isoelectric point7.50
Molecular weight84833.29
Publications
PubMed=29649280

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22132
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.55|      21|      28|      42|      69|       1
---------------------------------------------------------------------------
   42-   62 (37.97/35.94)	PRQVCFGLSMTAEQVSRCKDL
   73-   93 (34.58/16.39)	PFKVLLGGLIKQADLDNIKDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.43|      35|     530|     183|     219|       2
---------------------------------------------------------------------------
  183-  219 (58.26/47.78)	SFPQRTQSLRNW...YEKCARRIEKEEcnSNTFVKPLNLN
  713-  750 (55.17/37.29)	SMVDATQEIISFyecYEHYNDKLTREQ..INRFVKARGLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.45|      19|      32|     442|     460|       5
---------------------------------------------------------------------------
  442-  460 (34.13/24.33)	QCRFWTFTKEQLATMRQKL
  476-  494 (31.32/21.73)	QRHLNIYFNQQLIRLAKRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.14|      11|      22|     646|     656|       6
---------------------------------------------------------------------------
  646-  656 (19.13/14.39)	GQNASGAAAAA
  670-  680 (21.02/16.67)	GQQTPGAATDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.12|      17|      22|     496|     516|       9
---------------------------------------------------------------------------
  496-  516 (20.53/29.55)	IRQQS....MATAqVYMKrfySKVE
  517-  537 (24.59/15.96)	IRRTNpylvIATA.IYLA...CKIE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22132 with CycC domain of Kingdom Fungi
Unable to open file!