<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22098

Description Uncharacterized protein
SequenceMDVRARDNHGFQTLTKEAITLGYKDTVHGVEDCNEAKLTLVSDNTLWTKQNIVLQKDAVCKGLRAVNNAASRKRKTCHVYGVPLSGPALAKPGFYPEQKHCGEEQRKKWFEGLSQCKRPRALSEHVPSGVRKGMFEALFHHNVSFLRAMWFVKVVYLNVVRPPTGLASSVADKAPGRSKRMEVWTRDLISFMDTMLECACMPTGGSSSQGMKSASGGLPHQPIIPVVVGGAKGGGVDVLSLNPSTSLLGSQQGSSLSVTTTSQPGIGGSSPPTGSRSDIHAKWHYWVRLIGWQYNEGMINRAMLADWLLKQLQERKSLECWELLIPLVLVMVEGVALSQLHLRMLVDLITIWLKENYSVCGDGLRAPPPPPPPSRRLHTLCVSLIELLRYLIVSVPDSFVAFESFPKCVPIAIAHDNPTTGSGTMKSPGDRFRPVVHDNRAAGCGVHWLSMSQKAAGESTAKAWEQPPEGWREPVCGEVIKCVKERAGLLASAVNPAVLRNNLVMAVQALERALQTGDLISACKSVEDTLHGQLMGSTGWEDAKKGLVTDDQVVQFICEWGVSGLGHSGWGPTSPPPRCGRVVHGEGEDKARVYTAVSILRLKMEDLRCSGYGLQGGDGVQGGAGNAPGEMTHEMVFRWLDNHEPEGGAGDLNLHLLIAELAQEGMFFPDLYLHKLISEGILDKQRTVAERSRAWRHYLYLREMLITEDLEQPSCVGGEDGEGQDDLHGGRLRSAAAAAAAGTNPPETMAFLWGKQEEQSIRAKAFLNECHFVLHYFWGKRRKQLNRTRKDEEEYYIQKEEHEGGQVFPAMIEESDYLTVRKHRERIERVKAAVADMLHLPPEAGTGEWCRRDGASSEGGGKSEGADAKRKETGAAGEDQLHGGGNLLKKKTTLGAADTTDMKRRRVQKHIDSETQIDRAGAAIRGGDGCADLCPVDIITDEEELWWLKRSSKTRQEPNGGNQQVTSVTSPDYDATRRKEGGGGDFVSQGSDTALPGYCGRVNESESGSENLYHRCGAQWNGDQVQDRGTSGASTSVTAHIASEGPSRLGCSSGKAASISLETRRLSLRDKRKVSRWLDGVVRKLLGGSMRTDGSGDGNEGQSASGWSAHEAAGRWRLTEEEFTGILFVFDICQDYRLLVHFLLRLLRNPLLLHGTLAKPPSGTSGTPGKDRMGPSLLCRSCIGELSLVAGLRRYESMVVAMNLLPDMFSAVMVRAVELTSASALSQPGNGPLGAYAQDLLSRYKDIVTLGHCEGRWRFQLDHWVLGDAGSLRSGDSVNVDTGTDVHGIPRGDKMRGQLRKLANSILQSFRQVVHVAKGNLVGIERDAELGLKENLGRAELEKLRFKTMNRMDGVREVAMQVANAIQSFQSQNQHPQGVYIMAAGTALVISTVNCAVSMLQTLELGGGLQKYAQTARCAHRMIQMHVQSLAMVKEVLGPGLTPAMEDAVISEVLVQIHSAFGAGGRGVIRGAQQDSSAGGANTPVSAETAISAGGGGRGKQMMMAVGAAAFIVMAIVAGVLDWEKVIYSLRISEGLDQLQRGLTGLLSTASCGAGSKESSSRNEKTAAEVSLFLLRVLVGDCAGVSEGMVGDVVGAADLVGLTRVQRCANLEVVIRLGYKLFSAVIGPQKGLVHKNWPEKGGFWETLSGMANAAMRELIGHPPFREVCLRDSSVLYSLLSKEISPEVEIAEFLDANKIVDNAHRAFMLVPSTFRLFFSALRDQKMPCQQGDKWVFAGNPPPIGDLGGRDDSAISLKLPELVQILDNLQLGSFGLQWVELRLLLNEQVVLEKLSMGATAGEAIQAADTAQCKASLTDCEKVFIQAVVLTRLLTRPEAATLYSEAVRFLGRALEEQLISNVKSTVLENLDHLLGRRSLCQVLCNTIERFGLTSMMLSNAHLHPNRLKKSMLSWQSRKACSGSRRKRACSAENSKCLEHKELQASKRRLENGLKSVPFAAERALAELVLPRLASNSSTEGLNNILNDLIKQLHSLEQHISQLSRGILSQGVDAQCPKPSAWCGSEVYAAESSGLGQARRRIVPSQNVNVSTGAGAVAVSNAAAALQPSIWLRLGFLLPLLPFVYARDPWNMRHSLAHALLRLLATGVVQESMFPSLASNDCVLLQSNGGFTLSQAGGANTLEASAAATAAIATMGEGLFERLLSVFHALLSSVMPGWLKPKKKEKGSKVRAFEREIAEKMQQDLERFKLPRSIHNCIQAALPCFPLHPAPRVCAAPGILPSLTSTQAFPIVTEPQVSLSPCAHDAPPTHGMTAAQRALFISQCSAGGTPRAASVSAADVGSSGDCEVELDPWLLLEDGVASSSSVIGGPWGSSSGAGDRGNIKPCHWLKGAVRFSRMHLTYAGFVEDANT
Length2367
PositionKinase
OrganismChara braunii (Braun's stonewort)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Charophyceae> Charales> Characeae> Chara.
Aromaticity0.06
Grand average of hydropathy-0.202
Instability index44.78
Isoelectric point8.19
Molecular weight256172.83
Publications
PubMed=30007417

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22098
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.30|      14|      15|    2191|    2204|       1
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 2191- 2204 (24.16/12.68)	REIAEKMQQDLERF
 2208- 2221 (27.14/15.04)	RSIHNCIQAALPCF
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     279.75|      70|     107|     425|     494|       2
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  352-  396 (57.59/26.92)	.........................WLKENYSVCGDGLRAPP..PPPPPSRRlHTLCVSLIELLRY...LIVSVP
  425-  494 (126.22/68.51)	MKSPG..DRFRPVVHDNRAAGCGVHWLSMSQKAAGESTAKAW..EQPPEGWR.EPVCGEVIKCVKERAGLLASAV
  535-  597 (95.94/50.17)	MGSTGweDAKKGLVTDDQVVQFICEW.GVS..GLGHS...GWgpTSPP......PRCGRVVHGEGEDKARVYTAV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.16|      18|     107|     162|     186|       3
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  162-  186 (27.51/30.82)	PPTGLASSVADKapgrskrMEVWTR
  271-  288 (38.65/23.39)	PPTGSRSDIHAK.......WHYWVR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     314.05|     106|     113|    1766|    1878|       4
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 1766- 1878 (154.40/108.78)	NlQLGSFGLQWVelrLLLNEQVVLEKLSMGATAGEAIQAADTAQ....CKASLTDC.EKVFIQAvVLTRLLTRPEAATLYSEavRFLGRALEEQLISNVKSTVLEN.LDHLLGR.RSLCQ
 1882- 1994 (159.65/93.20)	N.TIERFGLTSM...MLSNAHLHPNRLKKSMLSWQSRKACSGSRrkraCSAENSKClEHKELQA.SKRRLENGLKSVPFAAE..RALAELVLPRLASNSSTEGLNNiLNDLIKQlHSLEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.44|      16|      16|    1029|    1044|       5
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 1029- 1044 (27.27/14.19)	GTS..GASTSVTAHIASE
 1045- 1062 (24.17/11.66)	GPSrlGCSSGKAASISLE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.09|      19|     107|     605|     623|       6
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  605-  623 (37.44/18.02)	EDLR...C.SGYGLQGGDGVQGG
  708-  730 (28.65/11.91)	EDLEqpsCvGGEDGEGQDDLHGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.94|      14|     107|     863|     878|       7
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  845-  858 (25.31/ 8.86)	GTGEWCRRDGASSE
  865-  878 (23.64/13.87)	GADAKRKETGAAGE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.58|      10|      15|     990|    1000|       8
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  990- 1000 (17.15/10.48)	GSDTaLPGYCG
 1008- 1017 (21.43/ 9.27)	GSEN.LYHRCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     343.54|      98|     500|     881|     984|       9
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  881-  984 (160.43/129.57)	LHGGGNLLKkktTLGAADTTDMKRRRVQKHIDSETQIDrAGAAIRG..GDGCAdLCPV..DIITDEEeLWWLKRSSKTRQEPNGGNQQVTSVTSPDYDA..........TRRKEGGGG
 1249- 1296 (64.78/37.36)	............TLGHCE....GRWRFQ..LDHWVLGD.AG.SLRS..GDSVN....V..DTGTD...VHGIPRGDKMR.......................................
 1403- 1497 (118.32/77.82)	LELGGGLQK......YAQTARCAHRMIQMHVQSL.......AMVKEvlGPG...LTPAmeDAVISEV.LVQI......HSAFGAGGRGVIRGAQQDSSAggantpvsaeTAISAGGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     154.52|      40|     502|    1641|    1680|      10
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 1641- 1680 (72.80/42.33)	GGFWETLSGMAN......AAMREL....IGHPPFREVCLRDSSVLYSLLS
 2086- 2121 (34.23/15.89)	...WNMRHSLAH......ALLRLLatgvVQESMFPSLASNDCVLL.....
 2125- 2168 (47.49/24.98)	GGFTLSQAGGANtleasaAATAAI..atMGEGLFE....RLLSVFHALLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.32|      23|     112|     624|     658|      11
---------------------------------------------------------------------------
  626-  648 (46.44/20.60)	NAPGEMTHEMVFRW.LDNHEPEGG
  660-  666 ( 0.41/ 8.70)	.................ELAQEGM
 1103- 1125 (31.47/ 7.47)	SASGWSAHEAAGRWrLTEEEFTG.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.20|      51|     507|    1523|    1578|      12
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 1527- 1578 (78.66/59.67)	IYSLRiSEGLDQLQRGLTGLLS.TASCGAGSKESSSRNEKTAAEVSL...FLLRVL
 2023- 2077 (75.55/42.60)	VYAAE.SSGLGQARRRIVPSQNvNVSTGAGAVAVSNAAAALQPSIWLrlgFLLPLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22098 with Med12 domain of Kingdom Viridiplantae
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