<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22072

Description Uncharacterized protein
SequenceMREPLLMEDGIRGKPPSGSPLLLRTQSPPPPPPPPPPPPSPSPAAAAAAAAAAAAAPSGPAAPLKNDNSTAVELHNGSSFPSLLALSPKKRAETVLSEMNDLTQTVVNLIRTSGLGLQPSVGSPKGGNFGTKVTGDDSAARGGEGDTSLPQKRGAGELSDLGSGLDQGSHLVPRTKDILQKMTSYQDLLASTLQELADVDEPSEECSKALSSQAVQNLSALRDFGLLLRGVERVLESTLEEFAAYKRPSLKRRGVESSQEDARMVVEGPSKQDLIDVQDLIAYAHKISYSTFAPPEFASGQAPLRGFQPPAPQDEHLRASQLYLVKDVDLGIPPEPILKDEDEDEEEEEEEEEEEEEEDEDDMEGEEEAAAGKLVTPLGAEKPPPDILPNIPPILPPGIGPVVPPPGWRPGMPVELPKDLLSGLPGLPGLPGLPGLPGLPGLPGLPGLPPGLELPPMPPGWKPGDPVPIDLPAPLPPVVPSEVAVTVPRPAVAKEPVATAAPTPSTATPTTTRPASRLTPPTAAPSSTAPQQLHPPTATPAAPPPPVLQPRPPTATAAAQLPPAPPAMPTTEAGVTHVPWVEIDLNPELSNSASSEPYSDEFEDDDDDDD
Length610
PositionMiddle
OrganismChara braunii (Braun's stonewort)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Charophyceae> Charales> Characeae> Chara.
Aromaticity0.03
Grand average of hydropathy-0.450
Instability index77.02
Isoelectric point4.35
Molecular weight63563.55
Publications
PubMed=30007417

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP22072
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.01|      20|      20|     377|     396|       4
---------------------------------------------------------------------------
  377-  396 (37.21/ 7.85)	P.LGAEKPPPDILPNIPPILP
  397-  417 (33.80/ 6.43)	PgIGPVVPPPGWRPGMPVELP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.33|      13|      15|     339|     351|       7
---------------------------------------------------------------------------
  339-  351 (23.18/13.04)	KDEDEDEEEEEEE
  356-  368 (24.15/13.86)	EEEDEDDMEGEEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.99|      21|      22|     212|     232|      11
---------------------------------------------------------------------------
  212-  232 (30.78/16.40)	SQAVQNLSALRDFGLLLRGVE
  236-  256 (32.06/17.36)	ESTLEEFAAYKRPSLKRRGVE
  258-  270 (19.14/ 7.64)	SQ........EDARMVVEGPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.10|      22|      48|     113|     134|      12
---------------------------------------------------------------------------
  113-  134 (37.38/25.83)	SGLGLQPSVGSPKGGNFGTKVT
  139-  157 (23.24/12.44)	AARGGEGDTSLPQKRGAGE...
  163-  183 (34.48/23.09)	SGLD.QGSHLVPRTKDILQKMT
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP22072 with Med4 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GIPPEPILKDEDEDEEEEEEEEEEEEEEDEDDMEGEEEAAAGKLVTPLGAEKPPPDILPNIPPILPPGIGPVVPPPGWRPGMPVELPKDLLSGLPGLPGLPGLPGLPGLPGLPGLPGLPPGLELPPMPPGWKPGDPVPIDLPAPLPPVVPSEVAVTVPRPAVAKEPVATAAPTPSTATPTTTRPASRLTPPTAAPSSTAPQQLHPPTATPAAPPPPVLQPRPPTATAAAQLPPAPPAMPTTEAGVTHVPWVEIDLNPELSNSASSEPYSDEFEDDDDDDD
2) MREPLLMEDGIRGKPPSGSPLLLRTQSPPPPPPPPPPPPSPSPAAAAAAAAAAAAAPSGPAAPLKNDNSTAVELHNGSSFPSLLALSPKKRAETVLSEMNDLTQTVVNLIRTSGLGLQPSVGSPKGGNFGTKVTGDDSAARGGEGDTSLPQKRGAGELSDLGSGLDQ
331
1
610
167

Molecular Recognition Features

MoRF SequenceStartStop
1) GSPLLLRTQSPPPPPPPPPP
2) MREPLLMEDGIRGKPP
3) PSPSPAAAAAAAAAAAAA
4) SEPYSDEFEDDD
5) WVEIDLNPEL
18
1
39
595
580
37
16
56
606
589