<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21946

Description Mediator of RNA polymerase II transcription subunit 8 (Fragment)
SequenceMEGSGSGSGSGLGSGLGSGEGQEKLNQAVQQQLNLKQMKNRAISLFKAISRILEDFDMYGRTNTTPKWQDILGQYSMVNLELFNMVDEMKKVSKAFAVNPKNVNAENASILPVMLSSKLLPEMETEENSKRDQLLEGMQNLPIATQIDKLKARLDMIAAACEGAEKVLADTRKAYCFGTRQGPSAIAIAPTLDKGQAAKIQEQENLLRAAVNLGDGLRIPGDQRHITPAAPPLHLADALPPLNDPQSFPDVSGSTTMYIKNTPNTIPAQTSLLQTSGSQLLGRSAASPSAATSTTSFDNTTASPIPYANSPRSSTNMMNTPSPQQQTPQQQQQQQQQQPPVQQQQQQRQKLMQLPQQQQQQLLAQQQQFRQSAMQGLGQLHGQHQMQFSQPLGHQQFRQLPSGHVQHGIGQSQLNQGNQMTRLSQFSGPANSALFSAAQTTANTQMIPNMSGTLPSQSVPPRMQFGLSGNNPQRSHASQMLSDQMFNMGGGNPGGMMSIQQQQQQHGSQAFGSMPSNAQNLQSGMVTLQNTQQNHPNFSQQRQQNPQEDLIAPPLHSPSV
Length560
PositionHead
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.04
Grand average of hydropathy-0.691
Instability index55.10
Isoelectric point8.97
Molecular weight60869.58
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21946
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.06|      24|      26|     324|     349|       1
---------------------------------------------------------------------------
  341-  362 (40.24/10.02)	VQQQQQQRQ................KLMQLPQQQQQQ..L
  363-  401 (28.00/ 6.99)	LAQQQQFRQsamqglgqlhgqhqmqFSQPLGHQQFRQLP.
  499-  516 (31.83/ 6.51)	IQQQQQQH......................GSQAFGSMPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.48|      20|      22|     285|     304|       3
---------------------------------------------------------------------------
  261-  279 (25.63/10.30)	.NTPNTIPAQTSLLQTSGSQ
  285-  304 (33.70/15.52)	AASPSAATSTTSFDNTTASP
  308-  323 (31.15/13.88)	ANSPR...SSTNMMNT.PSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     143.96|      27|     226|     231|     258|       4
---------------------------------------------------------------------------
  231-  258 (45.46/22.17)	PPlHLADALPPLNDPQ.SFPDVSGST...TMY
  434-  455 (31.00/10.38)	....LFSAAQTTANTQ.MIPNMSG.....TLP
  460-  486 (42.28/16.94)	PP.RMQFGLSG.NNPQrSHASQMLSD...QMF
  521-  546 (25.21/ 7.13)	....LQSGMVTLQNTQqNHPN..FSQqrqQNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.92|      30|     386|      14|      44|       6
---------------------------------------------------------------------------
   14-   44 (47.95/24.41)	SG.LGSGEGQEKLNQAvQQQLNLKQMKNRAIS
  402-  432 (50.97/22.74)	SGhVQHGIGQSQLNQG.NQMTRLSQFSGPANS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.13|      27|      60|      62|      90|       7
---------------------------------------------------------------------------
   62-   90 (43.52/36.58)	TNTTPKWQDILgqYSMVNLELFNMVDEMK
  125-  151 (44.61/30.01)	TEENSKRDQLL..EGMQNLPIATQIDKLK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21946 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRIPGDQRHITPAAPPLHLADALPPLNDPQSFPDVSGSTTMYIKNTPNTIPAQTSLLQTSGSQLLGRSAASPSAATSTTSFDNTTASPIPYANSPRSSTNMMNTPSPQQQTPQQQQQQQQQQPPVQQQQQQRQKLMQLPQQQQQQLLAQQQQFRQSAMQGLGQLHGQHQMQFSQPLGHQQFRQLPSGHVQHGIGQSQLNQGNQMTRLSQFSGPANSALFSAAQTTANTQMIPNMSGTLPSQSVPPRMQFGLSGNNPQRSHASQMLSDQMFNMGGGNPGGMMSIQQQQQQHGSQAFGSMPSNAQNLQSGMVTLQNTQQNHPNFSQQRQQNPQEDLIAPPLHSPSV
217
560










Molecular Recognition Features






MoRF SequenceStartStop




NANANA