<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21937

Description Mediator of RNA polymerase II transcription subunit 25 (Fragment)
SequenceMAEKQLIVAVESTAALGPYWETILMDYLDKIIRNHLLPMWSCLVQRTGWTRDPDVFFLWLSSIPFNGGGFNDAAIAEGLSEALMMFPNSQSGGSNQQSVDMHKHCILVGTSNPYPLQTPVYVPRPQNLEQSETIDSDPGNRLYDAEAVAKAFPQGKRNSRAADPPLEAKTPHFLILISEGFREARGALSRSGITSLPSNQSPVKVDAVSVTPVTGAPPTSLPSVNGSLANRQPVPAGNVPPATVKVEPVPVTSMVSGPAFPHNSSVPRAISTSQGVPSLQTSSPSSVSQDIMTNNENAQDTKPTMSMLQPLRPMNPAQANVNILNNLSQARQVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSMTSSGPLTVPAQVGQNSGLGSLTSNTSNLSSSSNIGISQPLGNLQGAVSMGQQVSGMSQGNLSGAQMVQGGVNMNQNVMSGLGPSVVSSGTGTMIPTPGMSQQVQSGMPLVNNAAVNMPLSQQTSGGIQSTQSKYVKVWEGSLSGQRQGQPVFITKLEGYRNSSASETLAANWPPVMQIVRLISQDHMNNKQYVGKADFLVFRAMNPHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKAFRLIGMLFPGPAAATNATAPADAITTAAASSTAATAAAAAAAFSHAATATSSAPTAAAATSTAAAAAATSSAPTAATGPTAATGPTAATGPTAAAFSAPTPTAASTNAATAAAASTSTTTLTTTAAAAAAFAVAATATSAATDGRCRNGSRLCSRPRAVTVGFSGTSFIAGSNEHRWRGLHELAQFFPGFHTTHT
Length820
PositionUnknown
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.05
Grand average of hydropathy-0.075
Instability index46.70
Isoelectric point9.03
Molecular weight84137.78
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21937
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     176.33|      17|      17|     671|     687|       1
---------------------------------------------------------------------------
  645-  658 (23.98/ 7.62)	P.ADAIT.T...AA.ASST.A
  659-  678 (23.69/ 7.43)	ATAAAAAAAfshAATATSS.A
  679-  697 (26.44/ 9.20)	PTAAAATST.aaAAAATSS.A
  698-  713 (27.52/ 9.90)	PTAATG.PT...AATGPTA.A
  716-  733 (24.26/ 7.80)	PTAAAFSAP...TPTAASTnA
  734-  749 (22.88/ 6.91)	ATAAAA.ST...STTTLTT.T
  750-  766 (27.56/ 9.93)	AAAAAAFAV...AATATSA.A
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     107.55|      22|      23|     423|     444|       2
---------------------------------------------------------------------------
  209-  228 (24.12/ 7.34)	SV.TPVTG.APPTSLPSV......NGSL
  306-  327 (24.67/ 7.68)	SMLQPLRPMNPAQANVNI......LNNL
  414-  435 (31.25/11.76)	SNLSSSSNIGISQPLGNL......QGAV
  436-  459 (27.51/ 9.44)	SMGQQVSGMS..Q..GNLsgaqmvQGGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.78|      24|      24|     362|     385|       3
---------------------------------------------------------------------------
  362-  385 (46.33/21.88)	MISSGMTSSVPAAQNVFSSGQS......GI
  466-  487 (23.97/ 7.87)	M..SGLGPSV......VSSGTGtmiptpGM
  490-  515 (35.48/15.08)	QVQSGMPLVNNAAVNMPLSQQT....sgGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.05|      24|     133|     252|     279|       4
---------------------------------------------------------------------------
  252-  279 (37.19/22.05)	TSMVSGPAFphnsSVPRAISTSQGVPSL
  386-  409 (40.86/16.26)	TSMTSSGPL....TVPAQVGQNSGLGSL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21937 with Med25 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ALSRSGITSLPSNQSPVKVDAVSVTPVTGAPPTSLPSVNGSLANRQPVPAGNVPPATVKVEPVPVTSMVSGPAFPHNSSVPRAISTSQGVPSLQTSSPSSVSQDIMTNNENAQDTKPTMSMLQPLRPMNPAQANVNILNNL
2) QVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSMTSSGPLTVPAQVGQNSGLGSLTSNTSNLSSSSNIG
187
332
327
423

Molecular Recognition Features

MoRF SequenceStartStop
NANANA