<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21934

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceMILNNAKNLKWRNSAYEFKFRVAFNQESIKNSDCALELNESQKMDQSQNPRPATATTPSRSFQFHPARGPILDLFNLYLGLGQNSRQKPEDSLREPPNKTQKRVHALNRELPPPNEQFILDFEQLQSQFPDQDQLRSVTEAILISLVVQCSGHGPRADFLLFVLRSLCGIGYVNWDSLLPSLLSSVSSAELPVSQLSQAAPTVSSSSLSQTGMLPPPSTIANSSNFQSSNPASPLTSVHTIGSPAQSTIEPLSCAAMSPVKSTDISSTGQQSKLRGSPSVRNNDISNSSLRQLCCKIILTGLEFSLKPVTYAEIFHHMLNWLVNWDQRQHGIDESDIIKLWRPDKAVIAWLHSCLDVIWLLVDEGKCRVPFYELLRSDLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRILNQTTPNVSGEAGAHQRLSPITYLSVLGEPLNGEDIASSVQKGSLDWERAVRCIRHALRTTPSPDWWRRVLVLAPCYRPSSQVPTAGAVFSSEMICEATIDRIVELLKLTNSGNNLLFLFICIGCIDFVDFVDKLVSRLTEGDHHILKTNHVTWLLALIIRIELVMNALNSDSRKVVETTRKILSFHREDRSSEPNNPQSILLDFVSSCQNLRIWSLNSSTREYLNNEQLQKGKQIDEWWRQASKGDRMMDYMNMDERSIGMFWVVTYTMAQPACETVMNWLNSAGVADLLPGTNLQPAERLMATREVSPLPMSLLSGFSMNLCMKLSYQMEDSLFSGQVIPSIAMVETYTRLLLLAPHSLFRSHFNHLVQRNPSLLSKPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISAIKGKRGDHRVFRLAENLCLNLIFSLRDFFYVKREGKGPTEFTETLNRVTVITLAILIKTRGIADADHLLYLQNMLEQIMATSHHTWSEKTLHHFPSVLREALSGRSDKRSLAIQTWQQAETTVIHQCTQLLSPSADPSYVMTYLSHSFPQHRQYLCAGALILMHGHAENINSGNLGRVLREFSPEEVTSNIYTMVDVLLHHMQIELQQGHSLQDLMLKACASLAFFVWTNELLPLDILLLALIDRDDDPHALHIVISLLFDRQELQQRVKLFCITRGHPEHWLYSGTFKRVELQKALGNHLAWKDRYPVFFDDIAARLLPVIPLIIYRLIENDAMDAAERLLAIYSPLLAYYPLRFTFVRDILAYFYGHLPGKLIVRILNVLDINKIPFSESFPQQISLTNPVMCPPLDYFTTLLLGIVNNVIPPLHNNSKSGSMGDVSNNTLRTAQSKPPAVSQSGPANAAEGQKAFYQIQDPGTYTQLVLETAVIEILSLPVSAFQIVQSLVQIVVNIQPTLIQSSNVLHGGSNSVGQGSVLPTSPSGGSTDSLGASRSTPSVSGINTSNFASRSGYTCQQLSCLLIQACGLLLAQLPSEFHSQLYSETTRIIKENWWLKDGTRSLGEIDSAVGYALLDPTWAAQDNTSTAIGNVVALLHSFFSNLPQEWLEGTNVLIKQLRPVTSVAMLRIAFRIIGPLLPKLANAHALFNKTLSSLLSILVDVFGKNPQTTIPIDASDTADIIDFLHHVVHYEGQGGPVQSSSKPRPEVLALIGRASESLRPDVQHLLSHLNPDVNSSVYAASHPKLVPNPT
Length1649
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.08
Grand average of hydropathy-0.079
Instability index48.11
Isoelectric point6.63
Molecular weight184517.70
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21934
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     296.01|      94|     102|    1214|    1315|       1
---------------------------------------------------------------------------
 1214- 1315 (150.29/114.26)	PGKLIVRILN..VLDINKIPFSeSFPQQISLTNPV..MCPPLDYFTTLLLGIVNNV.IPPLHNNSKSGSmgdvSNNTLRTAQSKPpavSQSGPANAAEGQKAFYQIQ
 1317- 1415 (145.72/90.50)	PGTYTQLVLEtaVIEILSLPVS.AFQIVQSLVQIVvnIQPTLIQSSNVLHGGSNSVgQGSVLPTSPSGG....STDSLGASRSTP...SVSGINTSNFASRSGYTCQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.61|      25|     102|     111|     138|       2
---------------------------------------------------------------------------
  111-  138 (37.75/36.36)	LPPPNEqfILDFEQLQSQFPdQDQLRSV
  214-  238 (45.86/30.16)	LPPPST..IANSSNFQSSNP.ASPLTSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     197.81|      57|     540|    1032|    1089|       3
---------------------------------------------------------------------------
  715-  748 (43.76/23.85)	.................DLLPGTNLQ.....PAERL...MATRE...............VSPLPMS...LLSGFSMN
  752-  823 (60.21/35.95)	KLSYQMEDSLFSgQVIPSIAMVETYTRLLLLAPHSL.FRSHFNHlvqrnpsllskpgvtLLVLEILnyrLLPL....
 1032- 1089 (93.83/65.02)	SNIYTMVDVLLH.HMQIELQQGHSLQDLMLKACASLaFFVWTNE...............LLPLDIL...LLALIDRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     228.44|      72|     325|    1118|    1201|       4
---------------------------------------------------------------------------
 1125- 1201 (117.17/110.76)	WLYSGTFKRVELQKALGNHL...AWKDRypvffDDIAARLLPVIPLI..IYRLIENDAMDAAERLLAIYSPLLAYYPLRFTF
 1453- 1529 (111.26/74.66)	WLKDGTRSLGEIDSAVGYALldpTWAAQ.....DNTSTAIGNVVALLhsFFSNLPQEWLEGTNVLIKQLRPVTSVAMLRIAF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.34|      19|     111|     578|     597|       9
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  578-  597 (28.97/24.13)	VTWLLALIIrIELVMNALNS
  692-  710 (38.37/26.97)	VTYTMAQPA.CETVMNWLNS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.21|      40|     614|     922|     963|      14
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  922-  963 (62.29/39.57)	MATSHHTWsEKTLHHFPSVLREALsGRSDKRSLAIQTWQQAE
 1539- 1578 (64.92/33.69)	LANAHALF.NKTLSSLLSILVDVF.GKNPQTTIPIDASDTAD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21934 with Med23 domain of Kingdom Viridiplantae
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