<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21933

Description ATP-dependent DNA helicase Q-like 4A (Fragment)
SequenceMRVLYNLEERSFSATPTSLSYDYYNLSSQSLFLGEAKSTKGVKCDDKIPQVNWSHHVNAHENFSFQAKFLSSNFLFSVPPKKPCHEEQNPGIAGFVVRRSENIQGSQRVQVEKAWIALSSLQNSSRNYVQPGKTVEVTPLLREDRRTTSFQGGYENNERRCPDATTTPIVINHSSLGLDGLVNNHPKYTGQINETLKCMADDIGDDDILENIDVDQIVENYQSTCTPKPSISKFPPITPTADKDNFARQRDNVLPPELCLDCIHGYKLGLCPEAASHLQELKDNLIAISNELLDNGENLNSTQIAKLRQDRSQLNKQIQLLEKYIHSGNLNEERKKSHFSASTAPPTSFMYETPQQTVLCNGPTRDGTQAYMGSGTYGSSFQCLPSFSVDKYGMSSTPVEREAFIPKIIEVNYIEGSGDKRWSSRDFPWTKELEVNNKKVFGNHSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMEWTEQQEILRELNSDYCKYKLLYVTPEKVAKSDVLLRHLDNLHVRELLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPNTPVLALTATATASVKEDVVQALGLVNCIIFRQSFNRPNLWYSVIPKTKKCLEDIDKFIRENHFDECGIIYCLSRMDCEKVAEKLQECGHKSAFYHGSMDPAQRASVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYSYSDYIRVKLMLSQGAIEQSPMTSGYNRSNMTNSGRILETNTENLMRMVSYCENDVDCRRLVQLVHFGEKFNSSTCQKTCDNCLKITSFIEKDVTEIAKQLVELVKLMGQRVSSSHVLEVYRGSLSQMVKKHRHETVSLHGAGKRLAKGEASRILHHLVVEDFLVEEVKKSDFYGSVSSILKVNEPKVRNLFAGQRIILRFPSSSVKASKPGKSDPTPAKGSLTSGKLNVTLIGTPAQPQTELDLTNLLQDLSAKLYTALRMLRTSLVREAGEGVMAYHIFGNATLQQISKRVPRTKEELLDINGISKTKVSKYGDRLLETIENTINEYYNLDKSSSKGSADSTKRRRETNGDPDANAEDDYDYDYDYAFTKSTGRSKKRTVKRQNRKAEIYSSAEEDYFHGCPDEDLDFDIIEIEAIDQVTCRNAAGRVLPQWTSS
Length1206
PositionUnknown
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.08
Grand average of hydropathy-0.492
Instability index45.89
Isoelectric point7.01
Molecular weight135787.17
Publications

Function

Annotated function
	RuleBase:RU364150
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP21933
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     297.71|      92|     156|       6|     103|       1
---------------------------------------------------------------------------
    6-  103 (150.67/121.37)	NLEERSFSATPTSLSYDYYNLSSQSLFLGEAKST....KGVKC.DDKIPQVNWSHHVNAHENF.SFQAKFLSSNFLFSVPPKKPCHEEQNpgiagFvVRRSENI
  156-  253 (147.04/102.03)	NNERRCPDATTTPIVINHSSLGLDGLVNNHPKYTgqinETLKCmADDIGDDDILENIDVDQIVeNYQSTCTPKPSISKFPPITPTADKDN.....F.ARQRDNV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.82|      43|     200|     614|     662|       2
---------------------------------------------------------------------------
  614-  662 (63.98/54.31)	SVKEDVVQALGLVNCIIFRQSFNRpnlwySVIPKT.KKCLEdIDKFIREN
  819-  862 (73.83/44.68)	SYCENDVDCRRLVQLVHFGEKFNS.....STCQKTcDNCLK.ITSFIEKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.71|      26|      49|     890|     915|       3
---------------------------------------------------------------------------
  890-  915 (41.62/32.44)	YRGSLSQMVKKHRHETVSLHGAGKRL
  916-  941 (34.93/25.87)	AKGEASRILHHLVVEDFLVEEVKKSD
  942-  966 (39.16/30.02)	FYGSVSSILKVNEPKVRNLF.AGQRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.95|      35|      36|    1096|    1131|       9
---------------------------------------------------------------------------
 1096- 1131 (56.67/46.38)	NEY.YNLDKSSSKgSADSTKRRRETNGDPDANAEDDY
 1133- 1168 (56.29/40.30)	YDYdYAFTKSTGR.SKKRTVKRQNRKAEIYSSAEEDY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.74|      27|     775|     278|     306|      12
---------------------------------------------------------------------------
  278-  306 (38.78/29.01)	LQELKDNLIAISNELLD.NGenLNSTQIAK
 1055- 1082 (39.96/23.56)	LQQISKRVPRTKEELLDiNG..ISKTKVSK
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21933 with Med34 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
1) DYDYDYDYAFTK
2) RIILRF
1130
965
1141
970