<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21931

Description Mediator of RNA polymerase II transcription subunit 33A (Fragment)
SequenceMEWDDEVREGVLKRLKSWQQHNNKPATAWVTELVEHLNSLGVGLPSPELGELLVSQICFDNNHPWMWKFMHNALSSRLLFPLQILSLLASNVIPYRHSQPHSFALFLPLLAQHAFSFLPTPSLPCNHKIVSSVDSALRFSEMYQIRDLELGHVFVLFFYEIIVALIDCMLIDWGFQVTFSKRMCLVVTATCDSEEYMDIDRNGTQGFKKSECHEQMRKRNSFTALEVLERLTESRKATILLQSVLLNMPEKFNCLQQRLQFLESLELASTELKLVNQVLTKVSANIRGVYRFDYCQSKHQLVGMLVDVGSCKTSLRCNYRLCQSPCWVPFDIYMENAMDSRQIPTKSAIDVLTVYFQKVMRIQFFPNIHELFAEGIKTLQILNQASWQETFLALWLSALRLVQRERDPPEGPIPHLVARLCVLLSIVPLAIANVLRDGSENNSSSVQVSKESEYRHEMKSDGSIKLGLISSVQVLGHFSGLLCPPTLVIDAANQAARKAASFIYNSMNGKGESGSGIHANSNAKAGGNLRHLIVEACIARDLLDTSVYFWPGYVSTSVLSLSDSSPLEKSPWSIFMEGTPLNNTLINSLTMTPASSLAEIEKLYYIALNGSDVERPAAAKILCGASLSHGWYIQEHVVHHMVKLLASPVPPSHSGSRSLLVDNMPMLSAVLRGASSIDTVHILSLHGVVPTVAASLLPLCEAFGSIKPTSNCTGDESSTSTYMAFSLAFLFLIRLWKFCRPPFDLCITELGVAVGGLEYILSLHNNHVMFSQDKLKSNPSLSESASVKPVYIDSFPKLRALYCQYKSCVASALSGISTGNSSHQTANMILSMIYQKITKGGISSSNSSSPTSSNACNTLINSGEDAFQRPMLPAWEVLEALPFVLESILTACVHGRLSSRDLTTGLRDLVDFLPASLAAIIDYFSSEVTRGVWKLVPMNGTDWPSPAALLQSVESEIKAILTHVGVEVPNCSSGGSPVMLPLPMAALVSLSITFKLDKSLEYMHAITGAALENCASGCPWPSMPIIGSLWAQKVRRWHNFIVVSGSRSVFRHNNESVAQLLRSCFTSFLGTLCVSTSKLTAEWSVNGLLGSTITAPGAYPYVAPGFLFLRSCRNIQNVQYVNDIIVGLVTEYSNELAGRRTGAGSRHIKSNEASLSLAAQSAKEVATLGASLICAAGGILLVQELYKETIPTWLLSSRDVKQNNDSVVSYILEGYAMAYLLILSGSIIWGVGTKLPSGTFTRRNRTIEVHLDFLAEVMEKKISLSCNPITWKCYVCCLVGLMVSLAPAWVQEVKVDTLRKLARGLSRWNEHELALSLLHRGGTTAMGALAELVNVIESEHILPCS
Length1345
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.08
Grand average of hydropathy0.139
Instability index46.61
Isoelectric point6.95
Molecular weight148112.56
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21931
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     749.23|     238|     329|     364|     618|       1
---------------------------------------------------------------------------
  364-  618 (370.79/228.59)	FFPnIHELFAEGIKTLQILNQASWQETFLALWLSAL...RLVQRERDPPEGPIPHLVARLCVLLSIVPLAIANVLRdgSENNSSSVQVSKESEYRHEMKSDGSIKL.GLISSVQ..VLGHFSGLLCPptlviDAANQAARKAASFIYNSMNGKGESGSgihaNSNAKAGGNLRHLIV...EACIARDLLDT.SVYFWPGYVSTSVLSLSDSSPLEKSPWSIFMEgtPLNNTLINSLTMTPASSLAEIEK..lyyIALNGSDVERPAA
  696-  948 (378.44/197.82)	LLP.LCEAFGSIKPTSNCTGDESSTSTYMAFSLAFLfliRLWKFCRPPFDLCITELGVAVGGLEYILSLHNNHVMF..SQDKLKSNPSLSESASVKPVYIDSFPKLrALYCQYKscVASALSGISTG.....NSSHQTANMILSMIYQKITKGGISSS....NSSSPTSSNACNTLInsgEDAFQRPMLPAwEVLEALPFVLESILTACVHGRLSSRDLTTGLR..DLVDFLPASLAAIIDYFSSEVTRgvwklVPMNGTDWPSPAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.25|      33|     948|     304|     337|       2
---------------------------------------------------------------------------
  304-  337 (61.68/51.04)	MLVDVGSCKTSLRCN...YRlCQSPCWVPFDIYMENA
 1253- 1288 (56.57/41.22)	FLAEVMEKKISLSCNpitWK.CYVCCLVGLMVSLAPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.61|      17|      41|     965|     982|       6
---------------------------------------------------------------------------
  965-  982 (29.80/19.85)	GVEVPNCSSGGS.PVMlPL
 1008- 1025 (30.81/16.07)	GAALENCASGCPwPSM.PI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.81|      21|      31|     225|     245|       8
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  225-  245 (31.18/21.36)	LEVLERLTESRKATILLQSVL
  259-  279 (31.63/21.79)	LQFLESLELASTELKLVNQVL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21931 with Med33 domain of Kingdom Viridiplantae
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