<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21929

Description Mediator of RNA polymerase II transcription subunit 33A (Fragment)
SequenceMEVPAQASEVDAWDEVLRQTKLAAETNSDPNVWAFQVTSTLRSSAISLPSAELAHRLVSHFFWDNHSAAAWKLLHTAMSLNILPYSLLIALLSATVVPSRKLYPTAYRLYMELLRQLHPMLERDIYSPNYENLHFFLSLLDNGEDSFNNDISYQWLHRIMKSIDDVLQLSQVYSQKLLEASLDDEGLLDHTTENKPRWLSRSHDMDIDGPDSFSEKKTEHVEGFHKKNTAVAIEIIAEILQHKVTSRILSLILEPLLKKSYHRRSSYWGSFIHQMQLLVSNSSVFRNLKHITAESLLLLTQNIHEIASREFKTKSKLETNVVIPAGSMMSFAGQSYGDSWSSLWLPIDLILEDALDGGQVAAFSAIEIITGLVKTLHAVNSTMWHNTFLGLWVAALRLVQRVGVVPTKLERDSREGPLPRLDTCMCMLLSITTLVVAHIIEEEEGQLIEEAEHSPTNQGKDKQALGKCHGELIASLQLLGDYESLLTPPQPVLVEANQAAAKAMMFVSGNPVAGNLRHLIVEACIAKDLLDTSAYFWPGYVNACSNQIPCSISNHASGWSSLMEGSQLTPGLVNVLVATPASSLAEIEKIYEIAINGSDEEKISAATILCGASLVRGWNVQEHTVLFITKLLSPVDPPNYSGAESHLTSQAPFLNVLLIGISSIDCVHIFSLHGLVPLLAPGLMLICEVFGSCAPDAPWTLATGEKLTRWDVFSNSFTLLLRFWRFDHLPVEQVRNDATSPPFGSLFSPECLLLVRNCKLASFGKTAKDRQRLKRLSKILHFPIEPVFMDSFPKLNFWHRKHQECIASIRSGLVPGGSVRQIVDALLGMMFRKVSNGAEPISPTTSGSSSSSGLALDDALMKLKVPAWNILEAIPFVLDAALTSCAYGRLSTRDLATGLKDLADFLPASLVSIASYFSAEVTRGIWKPAFMNGTDWPSPAANLSHVEQQIKKMLAATGVDVPSLTVDGNSPATLPLPLAAFVSLTITYKLDKAAERFLALVAPAMDALASGCPWPSLPIVTSLWIQKVKRWINYFVLSASRTVFHHNRDAVVQLLKCCFTSTLGLGSGCIYNNGGVSALLDHGFVSQVCNGVSPVAPGILYLRVYRSIGDITLLIEEIVPILMHSVTEIARSDLPKEGVKKPKKTKFGIKYGQVSLARSMIRVKRAALLGASLVWISGGPKLVQYLMSETLPSWFLSATVLEQDGGESGAMVAMLRGYALAFFVFLSAAFAWGIDNSQSPKRRVKVVGLHLQFLTSSLNRNTSMRCHNATWEAYVSGLISLMVSRAPSWVREVDVDLLKRLSWGLRQMDEHELALRLLEIGGIGVMGAAAETIIEFERRSLF
Length1342
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.08
Grand average of hydropathy0.125
Instability index46.22
Isoelectric point6.48
Molecular weight147904.25
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21929
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.32|      26|      29|    1169|    1197|       1
---------------------------------------------------------------------------
 1172- 1197 (47.85/37.02)	SLVWISGGPK..LVQYLMSETLPSW.FLS
 1199- 1227 (35.47/17.48)	TVLEQDGGESgaMVAMLRGYALAFFvFLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.62|      30|      33|     824|     854|       2
---------------------------------------------------------------------------
  552-  572 (30.27/17.21)	..........ISNHASGWSSLMEGSQLTPGL
  825-  854 (54.01/40.30)	ALLGMMF.RKVSNGAEPISPTTSGSSSSSGL
 1078- 1097 (22.35/ 6.80)	ALLDHGFvSQVCNGVSPVAP...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.78|      19|      33|     702|     722|       3
---------------------------------------------------------------------------
  702-  722 (26.90/22.94)	ATGEKLTrwDVFSNSFTLLLR
  738-  756 (34.88/20.92)	ATSPPFG..SLFSPECLLLVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.59|      37|     378|     252|     291|       7
---------------------------------------------------------------------------
  185-  221 (65.70/38.32)	EGLLDHTTENKPR.WLSRSHDMDIDGPDSFSEKKTEHV
  254-  291 (59.90/46.55)	EPLLKKSYHRRSSyWGSFIHQMQLLVSNSSVFRNLKHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.67|      10|      29|     625|     636|       8
---------------------------------------------------------------------------
  625-  636 (12.97/12.63)	VLFITklLSPVD
  656-  665 (16.70/ 8.60)	VLLIG..ISSID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.97|      19|      24|     121|     142|      10
---------------------------------------------------------------------------
  129-  151 (27.57/14.22)	NYENLHFFLSLLDNgedsFN.NDI
  152-  172 (24.40/10.22)	SYQWLHRIMKSIDD...vLQlSQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.89|      18|      31|     357|     375|      12
---------------------------------------------------------------------------
  357-  375 (25.38/24.29)	GGQVAAFSAIEIItGLVKT
  390-  407 (31.51/24.33)	GLWVAALRLVQRV.GVVPT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21929 with Med33 domain of Kingdom Viridiplantae
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