<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21918

Description Mediator of RNA polymerase II transcription subunit 16 (Fragment)
SequenceMAGHGDAVVNSPRDSVQFVEWSPTSCPRALLIANFHGRVTIWTQPSRGSANLVCDTSCWQREHEWRQDIAVVTKWLSGVSPYRWLSSKSSAPANLKSTFEEKFLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSQNGTTPKWFCTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVTPGPGNGFQVAPKTSITCGVPPLSPPNWSGFAPLAAYLFSWQDYLLSEAKQGKKQTDHNLGDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSIPPTNDFKNHQSPAIEMAADVQKVSESVSEKTKRVNFDPFDLPSDVRTLARVVYSAHGGEIAIAFLRGGVHVFSGPNFTPVDNYQINVGSAIAAPAFSSTSCCSASVWHDSSINCTILRIIRVLPPSVPISQVKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINSSALVPELWQASGETLSNIDPESMAVEPALIPSIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVASPTQSSATPATSQGPQNGTSSSMGSTQLQSWVQGAIAKISNTTDGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYIGVANRTADTNIQKPQSNAPAPGKVEEIAKPVSALVKSDDGQTGRAGAKGAEEVPSGRSRLGNGNAGQGYTFEEVKVLFMMLMDLCRRTAGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEDVDCVNDAPKLINSDPLDFSSLEHCDVYYGTHRLWPRKRRMSERDAAFGLNTSVGLGGYLGIMGSRRDVVTATWKTGLEGVWYKCVRCQRQTSAFASPDATASPSPHDREMWWISRWVYGCPMCGGTWARISIFWGELLSSQPTNNCQSCVKTLVYPACRFMHADVGALDVRMREKLRLVNQWKS
Length1158
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.08
Grand average of hydropathy-0.183
Instability index45.39
Isoelectric point6.96
Molecular weight125941.16
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21918
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.92|      17|     176|     286|     302|       1
---------------------------------------------------------------------------
  286-  302 (30.69/17.57)	GSGVTAVAFDPTR..AGSV
  458-  476 (24.23/12.29)	GSAIAAPAFSSTSccSASV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     378.96|     106|     114|     644|     753|       2
---------------------------------------------------------------------------
  138-  187 (45.38/19.78)	........................................................PSQNGTTPkwfCTSKGLL.GC...........GPSGIMAGDAIITDSGAMHVAGvPIVNPS.T.
  644-  753 (170.40/114.67)	LIPSIQAyVDSVLDlaSHFITRLRRYASFC....RT.LASHAVTAGTGSNRNmVASPTQSSATP...ATSQGPQNGTSSSMGSTQLQSWVQGAIAKISNTTDGGSNPTPN.PISGPS.TF
  762-  871 (163.18/96.27)	TFPGTPA.VRLIGD..CHFLHRLCQLLLFCfffrRTqLPRYIGVANRTADTN.IQKPQSNAPAP...GKVEEIAKPVSALVKSDDGQTGRAG..AKGAEEVPSGRSRLGN.GNAGQGyTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.85|      37|     114|     240|     278|       4
---------------------------------------------------------------------------
  240-  278 (60.13/43.50)	SEAKQGKKQTdhNLGDAVPLYCSPVSNFSAYVSP..EAAAQ
  351-  389 (65.72/40.76)	SMGGQPPMQT..VWQSKVDLSIPPTNDFKNHQSPaiEMAAD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.72|      16|     225|     212|     230|       7
---------------------------------------------------------------------------
  212-  230 (27.53/19.97)	GVPPLSPPNwsgFAPLAAY
  438-  453 (33.19/15.14)	GVHVFSGPN...FTPVDNY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.91|      16|     765|     118|     133|       9
---------------------------------------------------------------------------
  118-  133 (32.55/21.72)	LCVCSVFSSG.SVQLHW
  895-  911 (25.36/15.10)	LPVSQVGSSNiQVRLHY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21918 with Med16 domain of Kingdom Viridiplantae

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