<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21910

Description Mediator of RNA polymerase II transcription subunit 33A (Fragment)
SequenceMEGVAEMTKAAQQKGSDPLLWAVQMYSNLNSAGESLPSLELAEFLVSYICWDNNVPILWKFLEKALMLQIVPPMLLLALLSVRVIPCRHVQPAAYRLYLELVKRHAFELKSQINRPDYQKVMKSIDAVLHLSNIFGLSQSEPGILLLDASLGDEGLLEFTPDKKSRWATLYQDMELDRHDNYSDKKNEQHEKLQNANTLMAVEMIGQFFQDKISSRILYLARQNLPAHWLSFNQRLQLLGANSLALRKSRTLSPEAFLQLTSDSCMVLSRECKTNSQQKFQTVMSFEYLSSSASLCHGASHSALWIPLDLVLEDAMDGYQVSATSAIETISGLIKTLRAINGTSWHDTFLGLWLATLRLVQRERDPIEGPMPHLDTRLCMLLCIIPLVVADLIEEEERIPVDEKNSGPTDCWKEKNVPGQCRNDLVSSLQVLGDYQSLLTPPQSVAAAANQDAAKAMLFVSGITIGSAYFDCLSMTEMPVDCSGNMRHLIVEACIARNLLDTSAYSWPGYVNGRINQIPQCMPAHVPGWSSFMKGAPLTSVMINALVSSPATSLAELEKIFEIAIGGSEDEKISAAAILCGASLIRGWNIQEHTVHFILRLLSPPVPAENTEGNSYLINYAPILNVLFVGIASVDCVQIFSLHGLVPQLACSLMPICEVFGSCVPNISWTLTSGEEISAHAVFSNAFILLLKLWRFNRPPLEYGIGDVPTVGSQLTPEYLLLVRNSHLMSAGNIHKDRNRRRLSEIASLSSPNSVFVDSFPKLKVWYRQHQACIASTLSGLVHGTPFHQIVEGLLNMMFRKINRGSQTTITSGSSSSSGPANEDASIGPKLPAWDILEAIPFVVDAALTACAHGRLSPRELATGLKDLADFLPASLATIISYFSAEVTRGVWKPAFMNGTDWPSPAANLLNVEGQIRKILAATGVDVPSLASGDSSPATLPLPLAAFTSLTITYKVDKASERFLNLAGQTLESLAAGCPWPCMPIVASLWTLKAKRWSDFLIFSASRTVFLHNSDAVVQLLKSCFTATLGMNTSPISCSGGVGALLGHGFKSHLGGGICPVAPGILYLRAYRSIRDIVFLTEEILSILMHSVREIVCGELPRERLEKLKATKDGIKYGQVSLAASMSRVKLAAALGASLVWISGGLMLVQLLIKETLPSWFISVHRLDQEEKSDGMVAMLGGYALAYFAVLCGAFAWGVDSSSSASKRRPKVLGTHMEFLASALDGKISLGCDSATWRAYVSGFVSLMVGCTPNWVLEVDVHVLKRLSNGLRQLNEEELALALLGVGGVGTMGAAAELIIDTEI
Length1304
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.07
Grand average of hydropathy0.169
Instability index44.01
Isoelectric point6.07
Molecular weight142279.09
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21910
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.58|      22|      61|     862|     883|       2
---------------------------------------------------------------------------
  862-  883 (36.72/20.70)	ATGLKD...LA..DFLPASLATIISYF
  893-  910 (25.26/11.81)	KPAFMN...GT..DW.PSPAANLL...
  922-  947 (25.59/12.06)	ATGV.DvpsLAsgDSSPATLPLPLAAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.96|      49|     208|      87|     170|       3
---------------------------------------------------------------------------
  114-  170 (74.06/101.16)	NRPDYQKVMKSIDAVlhlsnifGlSQSEPGILLL..DASLGDEGLLEFTPDKK..SRWATL
  697-  749 (76.90/37.00)	NRPPLEYGIGDVPTV.......G.SQLTPEYLLLvrNSHLMSAGNIHKDRNRRrlSEIASL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.76|      15|      17|     324|     338|       6
---------------------------------------------------------------------------
  324-  338 (25.38/17.56)	TSAIETISGL.IKTLR
  343-  358 (24.38/16.54)	TSWHDTFLGLwLATLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     198.68|      64|     458|     519|     593|       7
---------------------------------------------------------------------------
  519-  593 (94.59/102.16)	PqCMPA.......HVPGWSSFMKGAPLTSVMINAlvSSPATSLaeLEKIFEIAIGgsedekISAAAILC..GASLIRGWNIQEH
  981- 1053 (104.08/77.49)	P.CMPIvaslwtlKAKRWSDFLIFSASRTVFLHN..SDAVVQL..LKSCFTATLG......MNTSPISCsgGVGALLGHGFKSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.77|      17|      17|    1072|    1088|      10
---------------------------------------------------------------------------
 1072- 1088 (28.05/18.50)	RSIRDIVF..LTEEILSIL
 1090- 1108 (25.73/16.34)	HSVREIVCgeLPRERLEKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.97|      19|     272|     492|     518|      13
---------------------------------------------------------------------------
  492-  518 (29.35/31.75)	EACIARNLldtsayswPGYVNGR.INQI
  771-  790 (31.62/16.12)	QACIASTL........SGLVHGTpFHQI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21910 with Med33 domain of Kingdom Viridiplantae
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