<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21897

Description U-box domain-containing protein 33 (Fragment)
SequenceMAVVSPEPATTQRMGSVRSPSDAGGEILEEPNPIVVDQPIYVAVTKEVKESKLNLIWAIQNSGGKRICIIYVHVRATMIPLLGGRFPASSLKEEQVQAYWEEERQGMHKTLNEYLRICHRMGVRAEKLYIEMDIIENGILELISQHGIRKLVMGAASDKSYNRRMMDLKSKKAIHVCRQAPAFCHIQFVCKGHLIHTRDRSLDEGNAEVASSLVQQVPNSVRSLRSQSITLGQDRRANLTNPAQDLLRRVRSANDGPRASFYPVSSPEDTEGFSTPRDRMGTEVSSDESDRLSRVSPALSTCSDNAVEPAFTPNLITEAGENALEFTLSRLIIEDIHHSPPPSTLDGGMDDTIYDQLQQALAEAQNATQNAYQETIRRREAEKEALGAMRKAKTSESLYTEELKLRKMVEEELRKEKEEFENMKSQRNRVKEELRLAIDQKASLESKIASSELMIKELEQKIVSAVDLLQNYKNERDELQIQRDNALREAEELRKKQGEPSCTHVPQLFSEFSFSEIKEATGNFNLSMKIGEGGYGNIFKGVLRHTDVAIKMLQSNSMQGPLEFQQEVDVLSKLRHPNLITLIGACPESWTLVYEYLPNGSLEDRLACKDNTPPLSWQTRIRVATELCSALIFLHSSKPHSIVHGDLKPSNILLDANLISKLSDFGICRILSNCESSSNNTTQFWRTDPKGTFVYMDPEFLASGELTPKSDVYSFGIILLRLLTGRPALGITKEVKYALDTGKLKSLLDPLAGDWPFVQAEQLARLALRCCDMNRKSRPDLYSDVWRILDAMRASSGGSNSFGLSSEGLLQPPSYFICPIFQEVMRDPHVAADGFTYEAEAIRGWLDGGHDNSPMTNSKLAHHNLVPNRALRSAIQDWLQPH
Length882
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.06
Grand average of hydropathy-0.442
Instability index51.37
Isoelectric point5.98
Molecular weight98965.33
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



ECO:0000256	ARBA:ARBA00003861

GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21897
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.57|      14|      20|     401|     414|       1
---------------------------------------------------------------------------
  401-  414 (23.76/15.06)	EELK.LRKMVEEELR
  421-  435 (20.80/12.34)	ENMKsQRNRVKEELR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.34|      41|     100|     356|     397|       3
---------------------------------------------------------------------------
  356-  397 (61.99/52.25)	QLQQALAEAQNATQNAYQE....TIRRREAEKEAlGAMRKAKTSES
  457-  501 (61.35/46.42)	ELEQKIVSAVDLLQNYKNErdelQIQRDNALREA.EELRKKQGEPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.23|      15|     101|     591|     605|       4
---------------------------------------------------------------------------
  591-  605 (27.94/15.75)	TLVY...EYLPNGSLEDR
  692-  709 (22.29/11.25)	TFVYmdpEFLASGELTPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.06|      12|      14|     297|     308|       7
---------------------------------------------------------------------------
  297-  308 (22.21/17.14)	PALST.CSDNAVE
  313-  325 (16.85/10.96)	PNLITeAGENALE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.36|      18|      30|     792|     809|       9
---------------------------------------------------------------------------
  792-  809 (29.94/21.57)	MRASSGGSNSFGLSSEGL
  825-  842 (31.43/23.05)	MRDPHVAADGFTYEAEAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.40|      25|      28|     736|     760|      10
---------------------------------------------------------------------------
  736-  760 (43.89/35.02)	KYALDTGKL..KSLLDPLAGDWPFVQA
  765-  791 (41.51/32.66)	RLALRCCDMnrKSRPDLYSDVWRILDA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21897 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DIHHSPPPSTLDGGMDDTIYDQLQQALAEAQNATQNAYQETIRRREAEKEALGAMRKAK
2) PRASFYPVSSPEDTEGFSTPRDRMGTEVSSDESDRLSRVSPALSTCSDNAVEPAFTPNLI
335
257
393
316










Molecular Recognition Features






MoRF SequenceStartStop




NANANA