<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21888

Description U-box domain-containing protein 35
SequenceMDRIQEADANNTSQRSSSSVVALAIKGNKKSKYVVQWALNKFVPEGMIIFKLIHVHAGIKGVPTPMGNVIPLSQVRNDVATAFRKEVEWQTNQMLQPFKRMCEQRKVHVDVVVIESDDVAVAVAEEVAKSAITKLVVGASSRGIFKSKQKGMSAKISVTTPRFCTIYVISKGKLSIRPSDMPITGSIIDDGSETSLSSSRSSNYASTSQTESASVSSYAGLHSSSLATQRFQALSSINHALLSTTSSLIESNHSRGQSLDIGRENTATSSARNSDIDHALSRVSSCKSFLSDTESWIHDQNSVKDGPLATSLPSPNRQAKFNLELEKLRIELRHAQGLHAVAQSEKIEASRKLNDLSKRRSEETQKMKEIIAKEEKAKELVKQERDKYQDASREAAYLKECAEREASERKETELKAIRATKEKEKLEDALSGSMPQYRKFTWDEIVSATSSFSEDLRIGMGAYGIVYKCILYHTTVAVKVLNTNENRKSKQFQQELEILSRIHHPNLLLLLGACPDHGCLVYEYMEHGNLEERLLRKNNTSPIPWFERFRIAWEVASALAFLHSSKPEPIIHRDLKPANILLGRNLVSKIGDIGLSTMLHSDNLSTMYKDTGPVGTLSYIDPEYQRTGLISPKSDVYAFGMVILQLLTAKPAIALAHKVETAIDDGNLTNILDPEAGAWPFQETLELAQLGLSCAELRRRDRPDLQDHVLPTLERLKEVADRAQHSASTVTIKSKPPNHFICPILQDVMDDPCVAADGYTYDRKAIEKWLEENDKSPMTNMALPHKHLIPNYTLLSAILEWKSRES
Length806
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.06
Grand average of hydropathy-0.412
Instability index44.89
Isoelectric point8.13
Molecular weight89873.25
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21888
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     231.61|      67|     217|     280|     348|       1
---------------------------------------------------------------------------
  171-  232 (85.74/58.79)	.......KGKLSIRPSDM...PITGSIIDDGSETSL.SSSRSSNYASTSQTESASVSSYAGLHSSSlATQRFQ
  234-  277 (44.02/26.40)	LSSIN..HALLSTTSSLIesnHSRGQSLDIGRENTATSSARNSDID...........................
  280-  348 (101.85/79.79)	LSRVSscKSFLSDTESWI...HDQNSVKDGPLATSLPSPNRQAKFNLELEKLRIELRHAQGLHAVA.QSEKIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.55|      26|     316|     379|     404|       2
---------------------------------------------------------------------------
  379-  404 (44.40/28.55)	ELVKQERDKYQDASREA.AYLKECAER
  696-  722 (39.15/24.35)	ELRRRDRPDLQDHVLPTlERLKEVADR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.99|      11|      39|      77|      87|       7
---------------------------------------------------------------------------
   77-   87 (19.14/13.28)	NDVATAFRKEV
  117-  127 (17.85/11.93)	DDVAVAVAEEV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21888 with Med32 domain of Kingdom Viridiplantae
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