<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21886

Description Mediator of RNA polymerase II transcription subunit 15a (Fragment)
SequenceMETKSKSTSASNMDTSNLNLMNSNNWRPNQGTNPTMDTSDWRAQLPHESRERIVNKIMDTLKKHLPVSGPDGLHELRKIAQRFEDKIFTDATSQDDYLRKISLKMLTMETKSQNTLASNIP
Length121
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.04
Grand average of hydropathy-0.960
Instability index22.74
Isoelectric point9.00
Molecular weight13835.44
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21886
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.39|      20|      21|      33|      52|       1
---------------------------------------------------------------------------
   13-   30 (21.27/ 8.29)	...MDTSNLNLMNS.......NNWRpNQ
   33-   52 (38.78/19.27)	NPTMDTSDWRAQLP.......HESR.ER
   55-   77 (18.35/ 6.45)	NKIMDT..LKKHLPvsgpdglHELR...
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21886 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) METKSKSTSASNMDTSNLNLMNSNNWRPNQGTNPTMDTSDWRAQLPHESRERIVNKIMDTLKKHLPVSGPDGLHEL
1
76










Molecular Recognition Features






MoRF SequenceStartStop




1) MNSNNWRPNQGT
2) TMDTSDWRAQLPHESRERIVNKIMDTLKKHLPVSGPDGLHELRKIAQRFEDKIFTDATSQDDYLRKISLKMLTMETK
21
35
32
111