<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21885

Description Mediator of RNA polymerase II transcription subunit 15a (Fragment)
SequenceMLTMETKSKNTLASNIPSNQVGPSNKPPDEGHVLQPHVPNLGQQHSIPLPSQLQPHQQFLSQNIQNNVVSQPNLPPVSSLGQPPSQNILQNSNIQNIPGPNSVGSTISQTSNLQNMFTGSQRQMPGRQQIVPPQQQLQSQNPQQFLYQQQLMKQKLHLSQMQQQQQQNLLQPNQLQSSQQSVMQPSMMQTSSLSSLPQTQQSTNVQQSTQSIPQQHAQVIRHQQQQTSIVNQQQTAVTQQSMLPAQQQQLMGAQPNTTNMQHAQMLGQQNSVGDIQQSQRMLSQQNNLTNLQQRQQQLINQQNNPANLHQQQLGNNGPGLQQQHLLGPESGNTDIQTSHHSAHMLQQPKVPMQQQSQQNTSNLLLPHAQQSQPLSSQQQLIPQIHTQPAQLQQQPNPSQRDMQQRIQASGSLLQQQNVLDQQKQLYHSQRTLQETSTTSLDSTSQTAQPSGVDWQEEVYQKLQTMKENYLPEMNEMYQKIAKKLQQHDSLPQQTKSDQIEKLRTYKMLLERMMALLQIPKNNILPDFKEKLVSYEKQIISLINSNRPRKGMSSVQLGQLPPNHMSSMQQSQSQVTQVQSHENQMNSQLQSTNLQVSVPTMQQNNIASLQHNSLSGVSTGQQNIMNSMQPGTNLDPGQGNSVNSLQQVPMSSLQQNPVSTPQQTNINSLPSQGGANVIQPNALQSGSSALQHQLKHQQEQQMLQNQQFKQYQQRHLMQRQLLQQQQQLHHPAKPQLSAQLQTHQMPQLHQMNDINDIKMHQGMGVKPGVFQQHHTSGQHSAYSHQQLKQGSAFPVSSPQLLQAASPQIQQHSSLTVDQQNHLPSKTKAATPLQSSNSPFVGPTPSPPLAPSPMPGESEKPIPCVSSISNAANIGHQQTGGAVASAQSLAIGTPGMSASPLLAEFSGPDGAHGNVLAATSGKSTVTEQPIERLINAVKSMSHKALSAAVRDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVSMTNCRLQARNFITQDGSNGIKRMKRYTSAIPLNVVSFTSSMNDSIKQFTASETSDVDSTATSSVKKPKIEVNHALMEEIREINHQLIDTVVHISNEDVDPTAAVAAAEGAEGIIVKCSFIAVALSPSLKSQYASAQMSPIQPLRLLVPANYPNCSPVLLDKFPVESSKENEDLSEKAKSRFSTSLRSLSQPMSLGEIARTWDVCARSVISEHAQRSGGGSFSSKYGTWEDCLTTKCATN
Length1218
PositionTail
OrganismMucuna pruriens (Velvet bean) (Dolichos pruriens)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Mucuna.
Aromaticity0.03
Grand average of hydropathy-0.730
Instability index67.82
Isoelectric point9.01
Molecular weight133891.30
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21885
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     527.29|      66|      66|     795|     860|       4
---------------------------------------------------------------------------
   70-  133 (47.06/ 7.25)	SQP........NLppvssL.gQPPS....QNI................LQ...........N.....S.........NI....QN.IP.......GPNSVG.....................STIsQTSNlqN..M....FTG............SQRQMPGRQ...QivPP.
  184-  251 (69.14/14.78)	.QP........SM.....M..QTSSlsslPQT................QQ...........S.....T.........NVQQSTQS.IP.......QQHAQV.....................IRH.QQQQ..T..S....IVNQQQTA..V...TQQSMLPAQQ...Q..QLM
  253-  337 (53.90/ 9.58)	AQPnttnmqhaQM.....LgqQNSV....GDIqqsqrmlsqqnnltnlQQ...........R.....Q.........QQLINQQNN.P.......ANLHQQ.........................QLGN..N.........GPGLQQ..Q...HLLGPESGNT...D..IQT
  346-  403 (56.28/10.39)	QQP........KV................P.M................QQ...........Q.....S.........QQ..NTSNLLL.......PHAQQS.....................QPL.SSQQ..QliP....QIHTQPAQ.lQ...QQPNPSQRDM...Q.....
  441-  484 (49.79/ 8.18)	DST........S.........QTAQ....P.....................................S.........G..VDWQEEVY.......QK...........................L.QTMK..E..N....YL.....P..E...M..NEMYQKI...A..KKL
  489-  564 (46.05/ 6.90)	SLP........Q.........QTKS....DQI................EKlrtykmllermM.....A.........LLQIPKNNILPdfkeklvSYEKQI.....................ISL.INSN..R..P....RKGMSSVQlgQ...LPP.............NHM
  565-  657 (47.77/ 7.49)	SSM........QQ.....S..QSQV....TQV................QS...........HenqmnSqlqstnlqvSVPTMQQNNIA.......SLQHNSlsgvstgqqnimnsmqpgtnlDPG.QGNS...........VN.......S...LQQVPMSSLQ...Q..NPV
  795-  860 (112.75/29.66)	SSP........QL.....L..QAAS....PQI................QQ...........H.....S.........SLTVDQQNHLP.......SKTKAA.....................TPL.QSSN..S..P....FVGPTPSP..P...LAPSPMPGES...E..KPI
  864-  928 (44.55/ 6.39)	SS..........I.....S..NAAN....IGH................QQ...........T.....G.........G.AVASAQSLA...........IG.....................TPG.MSA...S..PllaeFSGPDGAH..GnvlAATS...GKStvtE..QPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.78|      15|      16|     932|     946|       7
---------------------------------------------------------------------------
  932-  946 (23.98/15.42)	INAVKSMSHKALSAA
  950-  964 (24.80/16.21)	IGSVVSMNDRIAGSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.96|      26|     300|     404|     430|       8
---------------------------------------------------------------------------
  404-  430 (39.16/15.50)	QRiQASGSLLQQQNVLDQQKQLYHSQR
  712-  732 (36.31/10.77)	QR.....HLMQRQ.LLQQQQQLHHPAK
  734-  751 (27.49/ 6.01)	...QLSAQL..QTH...QMPQL.HQMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.81|      22|      47|    1103|    1124|       9
---------------------------------------------------------------------------
 1103- 1124 (38.38/22.43)	LSPSLKSQYASAQMSPIQPLRL
 1152- 1173 (36.44/20.84)	LSEKAKSRFSTSLRSLSQPMSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.22|      13|     115|      53|      68|      11
---------------------------------------------------------------------------
   53-   68 (19.86/13.24)	LQPHQQflsQNIQNNV
  170-  182 (23.36/ 7.71)	LQPNQL...QSSQQSV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21885 with Med15 domain of Kingdom Viridiplantae
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