<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21868

Description Kinase-like protein
SequenceMLDEWSSNILVTDPMRVYRSKRDAARKRVTDKYSILGFISSGTYGRVYKAQSKEADSRIHAIKKFKPDKEGDVVTYTGISQSAIREIALNREISHENIVSLKEVILEDKSIYMVFEYAEHDFLQVIHHHSQTLRSSITQPVLKSLTYQLLNGLLYLHDAHIIHRDLKPANILITSSGVVKIGDLGLARLTHQPLQPLFAGDKVVVTIWYRAPELLLGAKHYNKAVDIWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQKDQLLKIIEILGTPSERDWAKIKDLPEYQNMRRLDPFANRLGQWCQSRIQASGADLLSHLFAYDPDKRLTAAEALQHKWFLEAPQPTRNAFESLPSHQIPPHRRITVDDAPSMMPLPAAGSQAQAQVSQVQATAQANLSHSHSNQSGKAGSGASFASMSAGGTHTRKKARLG
Length432
PositionKinase
OrganismPolyporus brumalis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporaceae> Polyporus.
Aromaticity0.07
Grand average of hydropathy-0.351
Instability index44.30
Isoelectric point9.39
Molecular weight48291.69
Publications
PubMed=30061923

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21868
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.41|      21|      25|     159|     181|       1
---------------------------------------------------------------------------
  159-  181 (30.34/27.73)	AHIIHRDLKPanILITSSGVVKI
  187-  207 (36.07/25.47)	ARLTHQPLQP..LFAGDKVVVTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.56|      24|      29|      28|      55|       2
---------------------------------------------------------------------------
   28-   55 (31.43/29.81)	RVtdkYSILGFiSSGTYGRV..YKAQSKEA
   58-   83 (36.13/20.93)	RI...HAIKKF.KPDKEGDVvtYTGISQSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.95|      17|      17|     319|     335|       3
---------------------------------------------------------------------------
  319-  335 (29.71/17.32)	H.LFAYDPDKRLTAAEAL
  337-  354 (27.24/15.37)	HkWFLEAPQPTRNAFESL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21868 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFESLPSHQIPPHRRITVDDAPSMMPLPAAGSQAQAQVSQVQATAQANLSHSHSNQSGKAGSGASFASMSAGGTHTRKKARLG
350
432










Molecular Recognition Features






MoRF SequenceStartStop




1) HTRKKARLG
424
432