Description | Uncharacterized protein |
Sequence | MADRLTQLQDAVDQLANQFVASIYYTHKHHDLRTVSATDTVRADKKENEGASVDQDVEPYPTEQFKAGQRELAQDLILKEQQIEYLISVLPGLENSEKDQEQTIKQLEEDLKVAEEQRKEALQAKEAVLAKLDGVIRSIKRP |
Length | 142 |
Position | Middle |
Organism | Phialophora cf. hyalina BP 5553 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Pleuroascaceae> Venustampulla. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.765 |
Instability index | 43.13 |
Isoelectric point | 4.85 |
Molecular weight | 16172.88 |
Publications | PubMed=30018880 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669 ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP21854 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 50.43| 17| 33| 70| 86| 1 --------------------------------------------------------------------------- 70- 86 (27.90/15.55) RELAQDL.ILKEQQIEYL 105- 122 (22.52/11.47) KQLEEDLkVAEEQRKEAL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EALQAKEAV 2) RADKKENEGASVDQDVEPYPTEQFKAGQRELAQDLILKEQQIEYLISVLPGLENSEKDQEQTIKQLEEDLKVAE | 120 42 | 128 115 |
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