<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21841

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMESNGVNGIGKQAVSAGDARHPGKQKLTNGDTHSLYPTPNGVSPSSPVASLGSLPPELRHLDCGLSLGTLIERVAELCHRGVEDVILSLEKRPLPVANGIPPYTGNKPDVNQQKKKELMEIVNKHRTRFVKLMVLIQWSEQAGKQMGQMIDIKTWLHELQQCYDNAGKELAVMKRALQPLKIRSPDMETALAVLSTGKVPWMTDIGFLPSPPLKAKRMLKVLNTLDTMLNIRLVVHENLIPQLRNYRIANGRATFNFPSEFELDVYITGEDPALPFYFLDVRFLFNPAPQIADGFLRNEIEFKLNAILAENGLRGACDFIHSFILTHKISVLKRQAIEMSRGNWASSLHIEQVHRVLVVQYWTESPQSKSWLEIGIDSGKKKARRVASDKDAITSFLKVRWMRNGKEVPDATIPIELEELSFEQLLKRVVALHVGHILQSTHAKLENIKAALPAYAREMMKSNLARSDMETADTILTCQIGNHQAVTLTIDGVTGRPVISPANAVASLAQSDLENQKESANMHMVLMRYLAYDIQDSIYRQAERSGWKRMKIAVNEEDVRSKMGVDVLRYGFYHARGWKATKWYIAYSVTLSGESCNYTSDAYRLTECRRLPTKTISGVEPPLSSYHFRNIANFAARAISFWEANKSLVRLNVPNAIRYVFYNQEGHVDSPMEPSNSRTLPALCVRFSSLLKDFTFNDHFAADLLQISYIGFDTDLGAVRLQAKGMMRRPARLREILHRTRNDDLWLNSSGSFSLHLRTGLGTSCVNRLVAQLRTMGRVCNFADVLKQRGLECKDISLSRVVFTYANDLEMELLFTGIETTPVKLAIKPDNPHRRIGRLLEAVVNDGPNGFKSFTIALGFTLPLLSAFDTIDLRHMSSSVSDMPVIHARNPDHFRLSYTNPPCVFEIRMKRTKDKLEWIIQEAMTTAQREERAKTCPALNSTIMELFKSVDDGCSGMSSMIVADVKAVGIPLLQLDEAISAYTKTEPVPELVGDAPTVIMVD
Length1002
PositionTail
OrganismVenturia inaequalis (Apple scab fungus)
KingdomFungi
Lineage
Aromaticity0.07
Grand average of hydropathy-0.212
Instability index47.62
Isoelectric point8.90
Molecular weight112470.45
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21841
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     479.02|     160|     179|     440|     617|       1
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  440-  617 (228.46/211.46)	STHakLENIkAALPAYAREMMKSN..LARSDMETA.DTILTCQIGnHqaVTLTIDGVTGRPVisPANAV..ASLAQSDLENQKESANmhMVLMRYLAYDIQDSIYR.QAErsGWKRMKIAVNEEDVRSKMGvDVL..RYGFY..HAR...GWKATKWYIAYSVTLsGESCNYtSDAYRLtecRRLPTKTIS
  625-  797 (250.56/168.04)	SYH..FRNI.ANFAARAISFWEANksLVRLNVPNAiRYVFYNQEG.H..VDSPMEPSNSRTL..PALCVrfSSLLKDFTFNDHFAAD..LLQISYIGFDTDLGAVRlQAK..GMMRRPARLREILHRTRND.DLWlnSSGSFslHLRtglGTSCVNRLVAQLRTM.GRVCNF.ADVLKQ...RGLECKDIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.72|      14|      15|     258|     272|       2
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  258-  272 (22.54/18.80)	PSEFeLDV.YITGEDP
  275-  289 (24.18/14.81)	PFYF.LDVrFLFNPAP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.01|      14|      15|      39|      52|       3
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   39-   52 (24.68/15.95)	PNGVSPSSPVASLG
   55-   68 (26.33/17.57)	PPELRHLDCGLSLG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.50|      29|     105|     836|     865|       4
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  836-  865 (46.76/33.62)	IGRLLEAvVNDGPNGFKSFTIA..LGFTLPLL
  943-  973 (46.74/29.02)	IMELFKS.VDDGCSGMSSMIVAdvKAVGIPLL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.62|      13|      15|     296|     308|       5
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  296-  308 (21.36/12.40)	LRNEIEFKLNAIL
  313-  325 (24.26/14.99)	LRGACDFIHSFIL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21841 with Med14 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MESNGVNGIGKQAVSAGDARHPGKQKLTNGDTHSLYPTPNGVSPSSPVASL
1
51










Molecular Recognition Features






MoRF SequenceStartStop




NANANA