<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21839

Description Mediator of RNA polymerase II transcription subunit 5
SequenceMQIRNRAPKEQWETVVVGCLQQRIRREMFIKVVRELDNTTFISGQDLADILLEQQKLLPQTVDPLIPAYAETLLEEKRISTSDLLGALFKHSRQQANSKNEAESSDGSKATVSSSPAELEYQILDQLSKAYAPGGTRPSTQEEVRATLKVLGEWMSAVATEGDALLQPLDHQSVLMIDSLGMLGISMLENQKVIGVVEAAISKGLRKSLSHALTAFVPYWTHASPQHVQNATRLETGQRSRSLVDDTLNAESQEGTLDVAAALQLQAVVDLSIARCRPSIFAFINSLLVGCPLTDDSMMMGYLHVKYGSDIGTLAIDLTVAAFDILSSAVDRNESSQTLFALKSFLINKIPPLLSTLATSMFPPLTPQLCITQALQHVDLNIFPSFGMGMLTNSVLNEVRQEFIYGCILHGILPVDSVNQLLGETPFEPPPTPESKYHRDVLSQQCANEPGKAVQLIGELEKLDGNAGAIVGAVTETIRSACSTKETMSLKSMCNALSGKPQFLDVMMQFTSPASVLQPLCNLLDAWRFEDDQGEFQPVYDEFASIFLLVLAFVYRYQFSNTEMGISKDSFVAKYIVQGHQSLLAEELDDEQMKYLGSWIKGLYDPEGITEEVTGACRPQQFYMIVPTIFSQTMLVCAGGALDWDIVKNGLEYLHETFLLPSLVGAIYWMISCAGEQRGSDLTLLLQIIQRVTRAPSSPDAQPMHATILYIVAQPLTACLRSLQKQNPKRNDIESIISNLKPYVDFRRTSFTPCPELQTWRPQGGIRQNLKSVLQGLIIWGAGGGQQLSPPHYNPRLVLIAESVLGAPATLSVLLEEVKAQTEAPNGNAAVALDIATAFICAPKTENSPIHVGWQHSPVPVQATRGTKRLNLRDALKLEFDAATDLIQKDQTMAETVVRLHRAVEAQLNFSVAPMPDISGAAPMASLLPMTGNNASVVDQGMAFGTDTNAAGMDLGDGGLDISGTLMGDMKMDGNEDDIFGGGHSMGGNENDDDVFGGLDFSNLEGMGDSDYYQ
Length1014
PositionTail
OrganismVenturia inaequalis (Apple scab fungus)
KingdomFungi
Lineage
Aromaticity0.07
Grand average of hydropathy-0.066
Instability index43.58
Isoelectric point4.78
Molecular weight110645.99
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21839
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.49|      24|      33|     787|     810|       1
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  787-  810 (43.04/26.15)	QLSPPHYNPRLVL.IAESVLGAPAT
  821-  845 (37.44/21.82)	QTEAPNGNAAVALdIATAFICAPKT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.88|      13|      33|     634|     646|       2
---------------------------------------------------------------------------
  634-  646 (25.57/16.89)	MLVCAGGALDWDI
  670-  682 (24.31/15.67)	MISCAGEQRGSDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.58|      12|      37|     958|     969|       3
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  958-  969 (24.73/15.72)	GGLDISGTL.MGD
  997- 1009 (20.85/12.04)	GGLDFSNLEgMGD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.38|      25|      34|     716|     740|       4
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  716-  740 (41.89/25.11)	LTAC..LRSLQKQNPKRNDIESIISNL
  751-  777 (41.49/24.80)	FTPCpeLQTWRPQGGIRQNLKSVLQGL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.10|      31|      34|     341|     373|       6
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  341-  369 (43.22/32.57)	....AL.KSFL.INKIPPL.LSTLATSMFPPLTPQL
  370-  403 (41.14/39.56)	CItqAL.QHVD.LNIFPSFgMGMLTNSVLNEVRQEF
  407-  434 (32.74/22.94)	CI....lHGILpVDSVNQL.LG..ETPFEPPPTPE.
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21839 with Med5 domain of Kingdom Fungi
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