<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21833

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMPTDDDVQMADSQQPPSTTTAPSEPQRTDHEWQYYYLPSEPVEPLAPLTSQNLISLYNLNNLMNSVRRTDPVTGEKINKLRKSYEGKVKTLHLSGINKPSNDAAEFTNPGGKPLSEVPEGTKGFLDFEPEEWLHEKLHGRPIQAPAEDFQAKLDRALQMRPGAILEANKWDKIIGPPENKMKSSFEGARAVVPQSSTARNSPLLKASSSVRPERAGAKRRYTDQTYSGYGEGLSDDVGDSAHEEERKSAHINKKRRKDNMGVASPLSGPSYNAPGVMAGGSRSR
Length284
PositionHead
OrganismVenturia inaequalis (Apple scab fungus)
KingdomFungi
Lineage
Aromaticity0.06
Grand average of hydropathy-0.936
Instability index60.72
Isoelectric point7.04
Molecular weight31311.48
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21833
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.51|      19|      21|      35|      53|       1
---------------------------------------------------------------------------
   16-   31 (20.42/ 9.06)	...PS..TTTAPSEPQRTDHE
   35-   53 (32.31/18.30)	YYLPS..EPVEPLAPLTSQNL
   57-   77 (24.78/12.45)	YNLNNlmNSVRRTDPVTGEKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.78|      32|     100|      78|     109|       2
---------------------------------------------------------------------------
   78-  109 (55.00/31.87)	NKLRKSYEGKVKTLHLSGI..NKPSNDAAEFTNP
  179-  212 (48.79/27.58)	NKMKSSFEGARAVVPQSSTarNSPLLKASSSVRP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21833 with Med19 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GPPENKMKSSFEGARAVVPQSSTARNSPLLKASSSVRPERAGAKRRYTDQTYSGYGEGLSDDVGDSAHEEERKSAHINKKRRKDNMGVASPLSGPSYNAPGVMAGGSRSR
2) MPTDDDVQMADSQQPPSTTTAPSEPQRTDHEWQYYY
3) TLHLSGINKPSNDAAEFTNPGGKPLSEVPEGT
175
1
90
284
36
121










Molecular Recognition Features






MoRF SequenceStartStop




1) EPQRTDHEWQYYYLPSEP
2) HINKKRRK
3) KWDKII
4) TYSGYG
24
250
169
225
41
257
174
230