<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21831

Description Mediator of RNA polymerase II transcription subunit 6
SequenceMSASLENTVWSDPALIEYLNSYYVPEGFLPGINAESVHAYFLNSPFVDDMSNNALLRGQAAASPNGKWMFDRKALDAKLDRMEGIEYRIVEGPETSYGLAQLGNPVWVIRKQFREKKKSEARGEYYRVTRVEGTYFVMGELVYMAPSLEDVLRIRLMAATRAMQKFYKAAHELYFFSPDRGYSYHSTSKSSKSKVVLESTRTSRANSPVPDTASQTSAQPSTSNAKGETQSQPSDDRAIANSFQLAVRWGNEYMDENPLIGEPGALKLSSTSRQLKDQQEKVQANEASKAAQKLKEKEAESARASVTATPTPAPPAIKTSDLKKGSISKGKSPTSAVSEGGVKKRRKSTKPGTPGVASPTS
Length361
PositionHead
OrganismVenturia inaequalis (Apple scab fungus)
KingdomFungi
Lineage
Aromaticity0.08
Grand average of hydropathy-0.651
Instability index40.51
Isoelectric point9.41
Molecular weight39617.06
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21831
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.27|      31|     101|     198|     228|       1
---------------------------------------------------------------------------
  198-  228 (53.09/28.18)	ESTRTSRANSPVPDTAS.QTSAQPSTSNAKGE
  300-  331 (48.18/24.98)	ESARASVTATPTPAPPAiKTSDLKKGSISKGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.43|      22|      38|     124|     147|       3
---------------------------------------------------------------------------
  124-  147 (35.21/24.23)	EYYRVTRveGTYFVMGELVYMAPS
  165-  186 (41.22/22.90)	KFYKAAH..ELYFFSPDRGYSYHS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21831 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EYMDENPLIGEPGALKLSSTSRQLKDQQEKVQANEASKAAQKLKEKEAESARASVTATPTPAPPAIKTSDLKKGSISKGKSPTSAVSEGGVKKRRKSTKPGTPGVASPTS
2) SKVVLESTRTSRANSPVPDTASQTSAQPSTSNAKGETQSQPSDDRAIAN
252
193
361
241










Molecular Recognition Features






MoRF SequenceStartStop




1) AIKTSDLKKGSISKGKSPTSAVSEGGVKKRRKSTK
2) AQKLKEKEA
316
291
350
299