<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21823

Description F-box-like/WD repeat-containing protein TBL1XR1
SequenceMNFTSEELNYLIYRYLQESGFHHSCYTFGIESHIHRSNINGSSVPPGALISMVQKGMLYYYVDMTLKDEKNGENQNNHNNLENISLIDSIGKMSELSSGNLSYGVATNAKNDQQLTPDSQKKLTKDSKREENSDQRRSSESDVHSNSIHNSEIFAIKWHPNKELIATGSSDGTAKISQPNEVEATVLEHYPNEIDKRQPEASNGNCGISDRYAVTSIVWKPDGSQLLTACADGKGRIWQLDGKLVATLSNHTAPIFVCRWNIDGSLIAMGSADMRVTIWDSSSYEMKQCCDHHKGPVTDIDWQNVSIFATCSTDRSVAVCEVGSEKPIKSYEGHTSEINVVRWDPSSNLLASGSDDCTVKVWNLKQDKCVHDFRGHVRNIYAIKWCPVKRVVSCSCLASASADRTIRIWDVDRGICLYTLNRHQSPVYSLAFNSDGRLLASGSYDTAVNIWSLENGLLVRTVMIDGPVSDIDWHKDNRIVAVSGNGSSYVIDMRKNY
Length497
PositionTail
OrganismTrichoplax sp. H2
KingdomMetazoa
LineageEukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax> unclassified Trichoplax.
Aromaticity0.08
Grand average of hydropathy-0.477
Instability index46.06
Isoelectric point5.94
Molecular weight55453.32
Publications
PubMed=30042472

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21823
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     393.12|      40|      40|     306|     345|       1
---------------------------------------------------------------------------
  143-  180 (47.85/25.36)	...VHS..NSIHNSEIF....................AIKWH..P.....nkELIATGSS.DGTAKISQ.PN
  181-  241 (33.55/15.78)	EVEATV..LEHYPNEIDkrqpeasngncgisdryavtSIVWK..P.....dgSQLLTACA.DGKGRIWQLD.
  242-  283 (58.73/32.65)	GKLVAT..LSNHTAPIF....................VCRWNidG.......SLIAMGSA.DMRVTIWDSSS
  287-  324 (49.00/26.13)	KQCCDH..HKGPVTDID.......................W........qnvSIFATCST.DRSVAVCEVGS
  325-  366 (58.85/32.72)	EKPIKS..YEGHTSEIN....................VVRWD..P.....ssNLLASGSD.DCTVKVWNLKQ
  367-  413 (62.09/34.90)	DKCVHD..FRGHVRNIY....................AIKWC..PvkrvvscSCLASASA.DRTIRIWDVDR
  414-  455 (51.36/27.71)	GICLYT..LNRHQSPVY....................SLAFN..S.....dgRLLASGSY.DTAVNIWSLEN
  456-  487 (31.69/14.53)	GLLVRTvmIDGPVSDID.......................WH..K...............dNRIVAVSGNGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.07|      22|      40|      50|      71|       2
---------------------------------------------------------------------------
   50-   71 (38.51/23.83)	ISMVQKGMLYYYVDMTLKDEKN
   93-  114 (36.56/22.31)	MSELSSGNLSYGVATNAKNDQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21823 with Med16 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LSYGVATNAKNDQQLTPDSQKKLTKDSKREENSDQRRSSESDVHSN
2) TGSSDGTAKISQPNEVEATVLEHYPNEIDKRQPEASN
101
167
146
203










Molecular Recognition Features






MoRF SequenceStartStop




1) HNSEIFAIKWHPNKELI
2) LYYYVDMTL
3) VLEHY
4) YVIDMRKNY
149
58
186
489
165
66
190
497