<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21810

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSDLVQLKQILENVVGIGNGSEGASDVGILLTDITDQNGNHSISPVGNGNIFKAFFNYWQHSPQESDKERMEFIVNYIYSNANFHQMDAYFQLMVTAIDKGVIPARVVCETLLSTPLLRCNNDGYWKNTFQLIREVIRGVDYKCCRDLLKIILAKICQVESIENRTQLHLFHYAVRVLEYILDRDTCILPAYLSVNEVMAISLDVFPQDWLLTEVITRFINSFEGLATILTESGRPYLRPVVGYVGVLNSMWKLNPGNLKYVIKERIPYDAEYLMPQRELLRYLLLQPYSREIMQNVLSVSKGTFDPKLQNKCQWPLVEEVFVDVLITAMRESDDSEKSKILWQHLTSQLLHYIFFVHSISLKELLYEINLRRGRDYLMWTMLHCTCLVIQKQSLDEFIILIQLFEFLYPEKRPLPIPDCSKPTSVQALATACIWIQLSKKAELTKQNLGPVPEALSEQLKFIEDCFNKHLTTIDYHIAIVCNAYSINSDTQFVATNVILDACLGNGKTKVALPGLNCVASGATVPISSSLLDSLSVHVKSSFIYKVVNRISKMASTQAPLNLSPAVVETYSRILICNEVELFGIKQFVGQLFLQIVKSNAWNFLHAMLEILSYRLHHIQAHYRFQLLPHIYTLSGMSQTNTQQLQLSIENSALRLISGLSSCDVYPELSRSPNPEQLLSQESEELNKAFVLMLARAMHVTGLESPYGNWLENILRQIMEATPHCWPSHTLQCFPAPFKTFYNTHRHTPDSKATLRTKVDEEYRTWKSMGENETVNYFTQQNTSNVFLCVMWRLLLETNRLSSVCYRILERIGAKRWSSHIRVFADFIVYEFSSAAGSRHASKCIQILNDLIWKYNVVTLDRLILYLALRSHEGNEAQVCFFIIQLLLLKPAEFRTRVNSFVRDNSPCHWKQNDYYEKHMNYHRRWTEKFYFEGLQELSQSLPTSVNHYLPIYFGNVCLRFIPVLDIVIHRFIEMPPVSKSLETVLDHLGCLYKFHDRPITYLYDTLHYYEKHLINYPQIKKKLVGTITGAQRDIHAIGWYLSDGFQSYLSHVEEPDREPWKPTKTYYQDLVRRLINDILLNPTLVIKCCISVESQSIDCDWRFNEFANAASHFLYTSCVELLALPVTGQDVGRALFDLAPLNESFEARSSIMSWINAVALILVSLPETYWNVVYEKVLEILKTATPTNSGKRKFHSAFVDNFTYNQTKYNFLHHHRFMSESYPSYVLAMAHAIWHHSSIGQLTLMLRFLKDKVKPIIQTEEQFILVCHLVGPFLPRFHLERTRSLLKVVVDLYEMLLIVDQTSPTMNYVDTICDFFALISSYHIKYMFVGDSLKEEVDKIIPKLSSPLRLRLRFMTTQQVGDKQSLNVEWSH
Length1373
PositionTail
OrganismTrichoplax sp. H2
KingdomMetazoa
LineageEukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax> unclassified Trichoplax.
Aromaticity0.11
Grand average of hydropathy-0.053
Instability index44.09
Isoelectric point6.88
Molecular weight158807.74
Publications
PubMed=30042472

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21810
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.95|      13|      20|     964|     976|       1
---------------------------------------------------------------------------
  964-  976 (23.81/14.94)	VLDIV..IHRFIEMP
  985-  999 (20.13/11.43)	VLDHLgcLYKFHDRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.73|      12|      19|     259|     272|       2
---------------------------------------------------------------------------
  259-  272 (16.87/14.52)	LKYVIKEriPYDAE
  281-  292 (21.86/11.69)	LRYLLLQ..PYSRE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.17|      10|     282|     921|     946|       5
---------------------------------------------------------------------------
  909-  918 (20.93/10.66)	HWKQNDYYEK
  925-  934 (20.24/17.57)	RWTEKFYFEG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21810 with Med23 domain of Kingdom Metazoa
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