<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21807
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MEVNVSCYCIWPEEKENGLTNGIHTRSNCLARHTVCSGWSNRNLLAFSASSKSKLEDSINSDLPASFSIHLVNLEEPWRNHSFVSEHVSEIIQLAWDSHGTRLLSADSNGIIKTWQMQDNFINQWKCTSSNDLGEGEHVRAVRWLDTSAKEHYIDSKCKDKESFFEKFPYAVKKTPFVRYGGRPTQAWIAITATGMIYVTVLDPVTRGKLRLDLPSGYRLCISSADVTYNYQDSTFLAATSSGRKGDPVQIFCIKAQTMLVIMRYLNIYFLNHYLRPIQLSAELKACINTDSDEERNAIPKDSFVDQVRFLPQDAKSAPALLVLSSGYSQSTIQLFTLTTEPVLIHSAFNNPNLAERDIPVEEIWSCAAIYPCGEKVSCFSFSTFPIAPSSGDADYSKNANSHIMLACQKGNLILLNRSSLSIAAFCNTPFGAVDDPLDWAFGSDRTVKSISFSPCGLCTAVINGRGDVAICRIRMSSSFDNSGSECFSCYVTLLEYCLTTGIEYWDILHSISATFGPSIDVVSKMIAYIKNDLSKQAQPLRESLQLRFAVMCAALYRYGSDEHGRFVDQRCRIILYCICKFLHFEILHKYQSKNTESNPILKLEDACNSDTDGNLAATVSRLEATEYVLNPGVIHHVRAMIDWIGNYALLLAATVSAREIIQEAYGVTDMEVVRNLRMLLLLVSTWGQGNAAFYPRFYPQSDPVPSLSTIYRILTKVWMCYKNDNKLDSIIQYLSDKDQLPSLQSLMDTRGAFLCISDRLLLGPNIAFFRFGENPSTEPNMRYDVIRLMAINPFYNENLRQCVRCGGLSMITMNSSIDDNYNWNSRWIAKCICGGSWFKL |
Length | 841 |
Position | Tail |
Organism | Trichoplax sp. H2 |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax>
unclassified Trichoplax.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.111 |
Instability index | 40.95 |
Isoelectric point | 6.22 |
Molecular weight | 94640.98 |
Publications | PubMed=30042472
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP21807
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 46.41| 12| 27| 796| 808| 1
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796- 808 (22.67/17.41) YNENLR...QCVrCGG
822- 836 (23.73/12.98) YNWNSRwiaKCI.CGG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 70.76| 20| 163| 131| 150| 2
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131- 150 (35.44/28.69) NDLGEGEHVRAVRWLDTSAK
297- 316 (35.32/28.57) NAIPKDSFVDQVRFLPQDAK
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.40| 14| 33| 611| 624| 3
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611- 624 (25.72/16.03) DTDGN....LAATVSRLE
643- 660 (21.69/12.47) DWIGNyallLAATVSARE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 93.53| 26| 28| 434| 459| 7
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434- 459 (49.63/25.61) VDDPLDWAFGSDRTVKSI..SFSPCGLC
463- 490 (43.90/21.92) INGRGDVAICRIRMSSSFdnSGSECFSC
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