<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21805

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMSVLSADVIAEDLKAVFHQIDDEGNTSTQDQEKLQVCINALRNQHQIVSKDILEKTRLGKVVNNIRKKIANEDVKKQLKELLKQWQRDYLRGSNSILQNGDQMKRKFDDSNNVHDGDSQETEPKRIKKSLSDDTLDVINKPAIACIQIPRVESLPIIKNDSTVSTAMTSYGDNINASAFESAIENDNSDTSGVNNDLESLSPTIEIENKTCASTNASKVDKSDSESNDMASGYKIPIPSKVKELNMKADVKRIRKQQASVLDQLLNSISELETQAENNYVRKRSLRLRLDWGVKDKDINKIQNSSNENDISNKVDGVCGRYAFDGSWCTWNIPMPTPNDELVILPYTVFDYEFCFES
Length357
PositionUnknown
OrganismTrichoplax sp. H2
KingdomMetazoa
LineageEukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax> unclassified Trichoplax.
Aromaticity0.05
Grand average of hydropathy-0.705
Instability index43.27
Isoelectric point5.08
Molecular weight40212.49
Publications
PubMed=30042472

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21805
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.90|      22|      25|     241|     262|       1
---------------------------------------------------------------------------
  241-  262 (35.04/24.17)	VKELNMKADVKRIRKQQASV.LD
  268-  290 (30.86/20.51)	ISELETQAENNYVRKRSLRLrLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.48|      21|      23|      30|      52|       2
---------------------------------------------------------------------------
   30-   52 (29.79/25.89)	DQEKLQVCINALRnqHQIVSKDI
   54-   74 (32.69/21.10)	EKTRLGKVVNNIR..KKIANEDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.36|      17|      23|     171|     187|       3
---------------------------------------------------------------------------
  171-  187 (28.31/18.78)	GDNINASAFESAIENDN
  192-  208 (23.51/14.34)	GVNNDLESLSPTIEIEN
  216-  228 (14.53/ 6.03)	ASKVDKSDSES...ND.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21805 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GDQMKRKFDDSNNVHDGDSQETEPKRIKKSLS
2) NASAFESAIENDNSDTSGVNNDLESLSPTIEIENKTCASTNASKVDKSDSESNDMASGYK
100
175
131
234










Molecular Recognition Features






MoRF SequenceStartStop




NANANA