<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21803

Description Mediator of RNA polymerase II transcription subunit 27-B
SequenceMNGNSNGISTSNTDSNPSQNGSTSNDSTTVEANLLKLQDALHAIRELRWNVKDLFNDLNDQILAAHHQEDADTQTKNMTQLKQKLEDANTSIKHHLMQLSNAEFKSMPSLPPSSALPSLLLYDPQLEGKSTHQDLINSYEWNQNVKTNSKVIYQIMDKRQHEINFLQNENDDKLSRNADHDISNLQNIKNDILTRIGNSHEELVIDTSSNSGSLVKVTIKNTMTALIYITESLVISKVLVMAPEELNKAKTRTTSTYQVFKLVTLRATSASLHYYGNNTPAAALELFLNWLASYKNLFNSKCKYCNKYLSDYHTDYRYLPPCCRTLDDDHLAYHYECQPSN
Length341
PositionTail
OrganismTrichoplax sp. H2
KingdomMetazoa
LineageEukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax> unclassified Trichoplax.
Aromaticity0.07
Grand average of hydropathy-0.647
Instability index33.28
Isoelectric point5.99
Molecular weight38707.77
Publications
PubMed=30042472

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21803
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.62|      21|      45|     123|     148|       1
---------------------------------------------------------------------------
  123-  148 (27.00/29.44)	DPQLEGKSTHqDLINSyewnQNVKTN
  171-  191 (36.62/20.55)	DDKLSRNADH.DISNL....QNIKND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.64|      36|     240|      47|     101|       3
---------------------------------------------------------------------------
   47-   87 (57.20/44.31)	LRW..NVKDLFND...LNDQILAAHHqedadTQTKNMTQLKQKLED
  288-  328 (61.45/21.67)	LNWlaSYKNLFNSkckYCNKYLSDYH.....TDYRYLPPCCRTLDD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21803 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DQILAAHHQEDADTQTKNMTQLKQKLEDANTSIKHHLMQLSNAEFKSMP
2) MNGNSNGISTSNTDSNPSQNGSTSNDSTTVEA
60
1
108
32










Molecular Recognition Features






MoRF SequenceStartStop




NANANA